Case Report
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Year 2021, Volume: 11 Issue: 2, 371 - 374, 30.06.2021
https://doi.org/10.33808/clinexphealthsci.862928

Abstract

Kandida enfeksiyonları, her yaşta görülebilen, deri, mukoza, iç organ ve sistemlerin akut ve/veya kronik enfeksiyonlarıdır. Bu çalışmanın amacı kliniğimize psödomembranöz kandidiazis tanısı ile başvuran hastalarda teşhis ve tedavi yaklaşımının sunulmasıdır. Kliniğimize başvuran her iki hasta da Kronik Obstruktif Akciğer Hastalığı (KOAH) nedeniyle inhaler kullanmaktaydı. Yapılan intraoral muayenede 60 yaşındaki kadın hastada yumuşak damak sınırında ve farenkse doğru iki ayrı bölgede ve 70 yaşındaki erkek hastada palatinal bölge orta hatta lokalize psödomembranöz kandidiazis saptanmıştır. Hastalardan klinik muayenesi ile birlikte mikolojik olarak değerlendirilmesi amacıyla kültür alınmıştır. Her iki hastaya 10 günlük süre ile antifungal tedavi uygulanmıştır. Tedavi sonucunda iyileşme gözlenmiştir. Hastalarda yapılan aylık kontrollerde herhangi bir rezidiv izlenmemiştir.Oral kandidiazis olgularında antifungal ajanlar süspansiyon veya pomad halinde lokal olarak kullanılmalı, klinik tanıyı desteklemek için mikolojik olarak kültür yapılmalı ve hastalığın oluşumuna sebep olabilecek faktörler araştırılmalıdır.

References

  • 1.Laskaris, G. Fungal infections. In: Color Atlas of Oral Diseases Springer. Thieme, 4th ed. Stuttgart, 2005. p. 238-42.
  • 2. Liu X, Hua H. Oral manifestation of chronic mucocutaneous candidiasis: seven case reports. J Oral Pathol Med 2007;36:528–32.
  • 3. Motta-Silva AC, Aleva NA, Chavasco JK, Armond MC, França JP, Pereira LJ. Erythematous oral candidiasis in patients with controlled type II diabetes mellitusand complete dentures. Mycopathologia 2010;169:215–23.
  • 4. Muzyka BC, Epifanio RN. Update on oral fungal infections. Dent Clin North Am2013;57:561–81.
  • 5. Fukushima C, Matsuse H, Tomari S, Obase Y, Miyazaki Y, Shimoda T, Kohno S. Oral candidiasis associated with inhaled corticosteroid use: comparison of fluticasone and beclomethasone. Ann Allergy Asthma Immunol. 2003;90:646-51.
  • 6. Limbhore MV, Ramanojam S, Rathi P, Sane V, Mevawala A. Oral Candidiasis: An Overview And Case Report. Era J Med Res 2019; 6(2): 1-7.
  • 7. Singh A, Verma R, Murari A, Agrawal A. Oral candidiasis: An overview. J Oral Maxillofac Pathol. 2014;18(Suppl 1):S81-S85.
  • 8. Lyu X, Zhao C, Yan ZM, Hua H. Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis. Drug Des Devel Ther 2016 16;10: 1161-71.
  • 9. Millsop JW, Fazel N. Oral candidiasis. Clin Dermatol 2016 Jul-Aug;34(4):487-94.
  • 10. Farah CS, Lynch N, McCullough MJ. Oral fungal infections: an update for the general practitioner. Aust Dent J 2010;55 Suppl 1:48-54.
  • 11. Sawant B, Khan T. Recent advances in delivery of antifungal agents for therapeutic management of candidiasis.Biomed Pharmacother 2017;96: 1478-90.
  • 12. Patil A, Susmitha HR, Basappa S, Mahesh MS. Drug-induced Oral Candidiasis: A Case Report. IJSS Case Reports & Reviews 2016;2(12):1-4.
  • 13. McCullough MJ, Savage NW. Oral candidosis and the therapeutic use of antifungal agents in dentistry. Aust Dent J 2005;50: S36-9.
  • 14. Imron Nasution A. Virulence Factor and Pathogenicity of Candida albicans in Oral Candidiasis. G Patil S, ed. WJOUD 2013;4:267-271.
  • 15. Williams D, Lewis M. Pathogenesis and treatment of oral candidosis. J Oral Microbiol 2011; 3:3.
  • 16. Akpan A, Morgan R. Oral candidiasis. Postgrad Med J 2002;78: 455-9.
  • 17.Borahan MO, Keser G. Ağız Mukozasında Mantar Enfeksiyonları. İlgüy D, editör. Ağız Hastalıkları. Ankara: Türkiye Klinikleri 2018. p.71-6.
  • 18. Giannini PJ, Shetty KV. Diagnosis and management of oral candidiasis. Otolaryngol Clin North Am 2011;44(1):231-40.
  • 19. Krishnan PA. Fungal infections of the oral mucosa. Indian J Dent Res 2012;23(5):650-9.
  • 20. Compagnoni MA, Souza RF, Marra J, Pero AC, Barbosa DB. Relationship between Candida and nocturnal denture wear: quantitative study. J Oral Rehabil 2007;34(8):600-5.
  • 21. Williams DW, Kuriyama T, Silva S, Malic S, Lewis MA. Candida biofilms and oral candidosis: treatment and prevention. Periodontol 2000 2011;55(1):250-65.
  • 22.Figueiral MH, Azul A, Pinto E, Fonseca PA, Branco FM, Scully C. Denture related stomatitis: identification of aetiologicaland predisposing factors-a large cohort. J Oral Rehabil 2007;34(6):448-55.

Treatment Approach for Oral Candidiasis: Two Case Reports

Year 2021, Volume: 11 Issue: 2, 371 - 374, 30.06.2021
https://doi.org/10.33808/clinexphealthsci.862928

Abstract

Candida infections are acute and / or chronic infections of the skin, mucosa, internal organs and systems which may be seen at any age. The purpose of this study is to present diagnostic and therapeutic approach for patients who applied to our clinic with the diagnosis of pseudomembranous candidiasis. Both patients who referred to our clinic were using inhaler due to Chronic Obstructive Pulmonary Disease (COPD). Intraoral examination revealed pseudomembranous candidiasis localized on both the border of soft palate and through pharynx of a 60 year-old female patient and on the midline of hard palate of a 70-year-old male patient. Cultures were taken for mycological evaluation of the patients after clinical examination. Antifungal treatment was administered to both patients for 10 days. Healing was observed as a result of the treatment. No recurrence was observed at monthly follow-up assessments performed for patients. In cases of oral candidiasis, antifungal agents should be used locally in the form of suspension or pomade, evaluation of mycological culture should be performed to support clinical diagnosis and the etiological factors that may cause the disease should be studied.

References

  • 1.Laskaris, G. Fungal infections. In: Color Atlas of Oral Diseases Springer. Thieme, 4th ed. Stuttgart, 2005. p. 238-42.
  • 2. Liu X, Hua H. Oral manifestation of chronic mucocutaneous candidiasis: seven case reports. J Oral Pathol Med 2007;36:528–32.
  • 3. Motta-Silva AC, Aleva NA, Chavasco JK, Armond MC, França JP, Pereira LJ. Erythematous oral candidiasis in patients with controlled type II diabetes mellitusand complete dentures. Mycopathologia 2010;169:215–23.
  • 4. Muzyka BC, Epifanio RN. Update on oral fungal infections. Dent Clin North Am2013;57:561–81.
  • 5. Fukushima C, Matsuse H, Tomari S, Obase Y, Miyazaki Y, Shimoda T, Kohno S. Oral candidiasis associated with inhaled corticosteroid use: comparison of fluticasone and beclomethasone. Ann Allergy Asthma Immunol. 2003;90:646-51.
  • 6. Limbhore MV, Ramanojam S, Rathi P, Sane V, Mevawala A. Oral Candidiasis: An Overview And Case Report. Era J Med Res 2019; 6(2): 1-7.
  • 7. Singh A, Verma R, Murari A, Agrawal A. Oral candidiasis: An overview. J Oral Maxillofac Pathol. 2014;18(Suppl 1):S81-S85.
  • 8. Lyu X, Zhao C, Yan ZM, Hua H. Efficacy of nystatin for the treatment of oral candidiasis: a systematic review and meta-analysis. Drug Des Devel Ther 2016 16;10: 1161-71.
  • 9. Millsop JW, Fazel N. Oral candidiasis. Clin Dermatol 2016 Jul-Aug;34(4):487-94.
  • 10. Farah CS, Lynch N, McCullough MJ. Oral fungal infections: an update for the general practitioner. Aust Dent J 2010;55 Suppl 1:48-54.
  • 11. Sawant B, Khan T. Recent advances in delivery of antifungal agents for therapeutic management of candidiasis.Biomed Pharmacother 2017;96: 1478-90.
  • 12. Patil A, Susmitha HR, Basappa S, Mahesh MS. Drug-induced Oral Candidiasis: A Case Report. IJSS Case Reports & Reviews 2016;2(12):1-4.
  • 13. McCullough MJ, Savage NW. Oral candidosis and the therapeutic use of antifungal agents in dentistry. Aust Dent J 2005;50: S36-9.
  • 14. Imron Nasution A. Virulence Factor and Pathogenicity of Candida albicans in Oral Candidiasis. G Patil S, ed. WJOUD 2013;4:267-271.
  • 15. Williams D, Lewis M. Pathogenesis and treatment of oral candidosis. J Oral Microbiol 2011; 3:3.
  • 16. Akpan A, Morgan R. Oral candidiasis. Postgrad Med J 2002;78: 455-9.
  • 17.Borahan MO, Keser G. Ağız Mukozasında Mantar Enfeksiyonları. İlgüy D, editör. Ağız Hastalıkları. Ankara: Türkiye Klinikleri 2018. p.71-6.
  • 18. Giannini PJ, Shetty KV. Diagnosis and management of oral candidiasis. Otolaryngol Clin North Am 2011;44(1):231-40.
  • 19. Krishnan PA. Fungal infections of the oral mucosa. Indian J Dent Res 2012;23(5):650-9.
  • 20. Compagnoni MA, Souza RF, Marra J, Pero AC, Barbosa DB. Relationship between Candida and nocturnal denture wear: quantitative study. J Oral Rehabil 2007;34(8):600-5.
  • 21. Williams DW, Kuriyama T, Silva S, Malic S, Lewis MA. Candida biofilms and oral candidosis: treatment and prevention. Periodontol 2000 2011;55(1):250-65.
  • 22.Figueiral MH, Azul A, Pinto E, Fonseca PA, Branco FM, Scully C. Denture related stomatitis: identification of aetiologicaland predisposing factors-a large cohort. J Oral Rehabil 2007;34(6):448-55.
There are 22 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Gaye Keser 0000-0001-7564-4757

Filiz Namdar Pekiner 0000-0001-7426-5587

Publication Date June 30, 2021
Submission Date January 18, 2021
Published in Issue Year 2021 Volume: 11 Issue: 2

Cite

APA Keser, G., & Namdar Pekiner, F. (2021). Treatment Approach for Oral Candidiasis: Two Case Reports. Clinical and Experimental Health Sciences, 11(2), 371-374. https://doi.org/10.33808/clinexphealthsci.862928
AMA Keser G, Namdar Pekiner F. Treatment Approach for Oral Candidiasis: Two Case Reports. Clinical and Experimental Health Sciences. June 2021;11(2):371-374. doi:10.33808/clinexphealthsci.862928
Chicago Keser, Gaye, and Filiz Namdar Pekiner. “Treatment Approach for Oral Candidiasis: Two Case Reports”. Clinical and Experimental Health Sciences 11, no. 2 (June 2021): 371-74. https://doi.org/10.33808/clinexphealthsci.862928.
EndNote Keser G, Namdar Pekiner F (June 1, 2021) Treatment Approach for Oral Candidiasis: Two Case Reports. Clinical and Experimental Health Sciences 11 2 371–374.
IEEE G. Keser and F. Namdar Pekiner, “Treatment Approach for Oral Candidiasis: Two Case Reports”, Clinical and Experimental Health Sciences, vol. 11, no. 2, pp. 371–374, 2021, doi: 10.33808/clinexphealthsci.862928.
ISNAD Keser, Gaye - Namdar Pekiner, Filiz. “Treatment Approach for Oral Candidiasis: Two Case Reports”. Clinical and Experimental Health Sciences 11/2 (June 2021), 371-374. https://doi.org/10.33808/clinexphealthsci.862928.
JAMA Keser G, Namdar Pekiner F. Treatment Approach for Oral Candidiasis: Two Case Reports. Clinical and Experimental Health Sciences. 2021;11:371–374.
MLA Keser, Gaye and Filiz Namdar Pekiner. “Treatment Approach for Oral Candidiasis: Two Case Reports”. Clinical and Experimental Health Sciences, vol. 11, no. 2, 2021, pp. 371-4, doi:10.33808/clinexphealthsci.862928.
Vancouver Keser G, Namdar Pekiner F. Treatment Approach for Oral Candidiasis: Two Case Reports. Clinical and Experimental Health Sciences. 2021;11(2):371-4.

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