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Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report

Year 2021, Volume: 11 Issue: 4, 884 - 887, 26.10.2021
https://doi.org/10.33808/clinexphealthsci.703341

Abstract

Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a systemic disease associated with high morbidity and mortality rates, caused by dysregulation of the alternative complement pathway, leading to uncontrolled complement activation resulting in thrombotic microangiopathy. In this case it’s reported patient care management of a P-aHUS patient which developed in postpartum period with renal failure, anasarca edema, hypertension and important laboratory signs of the syndrome. Patient was effectively treated by hemodialysis and eculizumab therapy, which controls complement activation and discharged without signs of hemolysis. The patient was discharged to home from the hospital after 42 days. At follow-up 2 weeks after discharge, all signs and symptoms of renal failure had resolved. The patient has not had any inpatient readmissions to the hospital to date. There are no case report in P-aHUS nursing care. Discussion of this case contributes the literature describing nursing interventions associated with caring for patients with P-aHUS.

Thanks

Thank you to Mrs M.K. for sharing her health story with us.

References

  • 1. Dashe JS, Ramin SM, Cunningham FG. The long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy. Obstet Gynecol 1998; 5: 662-668.
  • 2. Furlan M, Robles R, Galbusera M, Remuzzi G, Kyrle PA, Brenner B, Krause M, Scharrer I, Aumann V, Mittler U, Solenthaler M, Lammle B. von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998; 339:1578-1584.
  • 3. Levy GG, Nichols WC, Lian EC. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001; 6855:488-494.
  • 4. Robson JS, Martin AM, Ruckley VA, Macdonald MK. Irreversible post-partum renal failure. A new syndrome. QJ Med 1968; 147:423-435.
  • 5. Ardissino G, Wally OM, Baffero GM, Rigotti A, Cugno M. Eculizumab for atypical hemolytic uremic syndrome in pregnancy. Obstet Gynecol 2013; 2:487-489.
  • 6. Ackley BJ, Ladwig GB. Nursing diagnosis handbook: an evidence-based guide to planning care. 10th ed. Maryland Heights, Missouri: Mosby Elsevier; 2014.
  • 7. Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, Essig M, Ribes D, Dragon Durey MA, Bridoux F, Rondeau E, Fremeaux-Bacchi V. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol 2010; 5:859-867.
Year 2021, Volume: 11 Issue: 4, 884 - 887, 26.10.2021
https://doi.org/10.33808/clinexphealthsci.703341

Abstract

References

  • 1. Dashe JS, Ramin SM, Cunningham FG. The long-term consequences of thrombotic microangiopathy (thrombotic thrombocytopenic purpura and hemolytic uremic syndrome) in pregnancy. Obstet Gynecol 1998; 5: 662-668.
  • 2. Furlan M, Robles R, Galbusera M, Remuzzi G, Kyrle PA, Brenner B, Krause M, Scharrer I, Aumann V, Mittler U, Solenthaler M, Lammle B. von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998; 339:1578-1584.
  • 3. Levy GG, Nichols WC, Lian EC. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001; 6855:488-494.
  • 4. Robson JS, Martin AM, Ruckley VA, Macdonald MK. Irreversible post-partum renal failure. A new syndrome. QJ Med 1968; 147:423-435.
  • 5. Ardissino G, Wally OM, Baffero GM, Rigotti A, Cugno M. Eculizumab for atypical hemolytic uremic syndrome in pregnancy. Obstet Gynecol 2013; 2:487-489.
  • 6. Ackley BJ, Ladwig GB. Nursing diagnosis handbook: an evidence-based guide to planning care. 10th ed. Maryland Heights, Missouri: Mosby Elsevier; 2014.
  • 7. Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, Essig M, Ribes D, Dragon Durey MA, Bridoux F, Rondeau E, Fremeaux-Bacchi V. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol 2010; 5:859-867.
There are 7 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Hafize Özdemir 0000-0002-7714-9925

Mehmet Alkanat 0000-0001-8079-3749

Publication Date October 26, 2021
Submission Date March 13, 2020
Published in Issue Year 2021 Volume: 11 Issue: 4

Cite

APA Özdemir, H., & Alkanat, M. (2021). Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report. Clinical and Experimental Health Sciences, 11(4), 884-887. https://doi.org/10.33808/clinexphealthsci.703341
AMA Özdemir H, Alkanat M. Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report. Clinical and Experimental Health Sciences. October 2021;11(4):884-887. doi:10.33808/clinexphealthsci.703341
Chicago Özdemir, Hafize, and Mehmet Alkanat. “Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report”. Clinical and Experimental Health Sciences 11, no. 4 (October 2021): 884-87. https://doi.org/10.33808/clinexphealthsci.703341.
EndNote Özdemir H, Alkanat M (October 1, 2021) Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report. Clinical and Experimental Health Sciences 11 4 884–887.
IEEE H. Özdemir and M. Alkanat, “Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report”, Clinical and Experimental Health Sciences, vol. 11, no. 4, pp. 884–887, 2021, doi: 10.33808/clinexphealthsci.703341.
ISNAD Özdemir, Hafize - Alkanat, Mehmet. “Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report”. Clinical and Experimental Health Sciences 11/4 (October 2021), 884-887. https://doi.org/10.33808/clinexphealthsci.703341.
JAMA Özdemir H, Alkanat M. Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report. Clinical and Experimental Health Sciences. 2021;11:884–887.
MLA Özdemir, Hafize and Mehmet Alkanat. “Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report”. Clinical and Experimental Health Sciences, vol. 11, no. 4, 2021, pp. 884-7, doi:10.33808/clinexphealthsci.703341.
Vancouver Özdemir H, Alkanat M. Nursing Care in Postpartum Atypical Hemolytic Uremic Syndrome: A Case Report. Clinical and Experimental Health Sciences. 2021;11(4):884-7.

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