Research Article

A COMPARATIVE STUDY OF ZERO-ORDER AND DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RIVASTIGMINE IN SINGLE DOSAGE FORM

Volume: 50 Number: 01 January 1, 2004
  • S. Dermiş Güngör
EN

A COMPARATIVE STUDY OF ZERO-ORDER AND DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RIVASTIGMINE IN SINGLE DOSAGE FORM

Abstract

In this study zero-order, first and second derivative spectrophotometric methods were applied to the determination of Rivastigmine (RVT) in capsules. UV-spectrum, first derivative and second derivative spectrums of RVT were plotted in the spectral range of 230-280 nm. Zero-order, first derivative and second derivative absorbance values were measured at maximum wavelenghts for this three methods. Lineer calibration graphs were found in the working range of 0.2 mM -1.0 mM (80 - 400 pg ml1). All three methods were statistically compared with each other and significant results were obtained

Keywords

References

  1. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering

Details

Primary Language

English

Subjects

Chemical Engineering

Journal Section

Research Article

Authors

S. Dermiş Güngör This is me
Türkiye

Publication Date

January 1, 2004

Submission Date

December 31, 2004

Acceptance Date

-

Published in Issue

Year 1970 Volume: 50 Number: 01

Vancouver
1.S. Dermiş Güngör. A COMPARATIVE STUDY OF ZERO-ORDER AND DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RIVASTIGMINE IN SINGLE DOSAGE FORM. Commun. Fac. Sci. Univ. Ank. Ser. B. 2004 Jan. 1;50(01):14-23. doi:10.1501/Commub_0000000356

Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering

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