BASED ON QUARTZ CRYSTAL MICROBALANCE

Volume: 58 Number: 1.2 June 1, 2016
Serap Durkut , Şükran Şeker
EN TR

BASED ON QUARTZ CRYSTAL MICROBALANCE

Abstract

In this study, a genosensor based on quartz crystal microbalance QCM has been developed for the detection of single-stranded oligonucleotide specific to alpha-fetoprotein AFP gene. The quartz crystals were coated with polyethyleneimine PEI and then crosslinked with glutaraldehyde GA . The oligonucleotide probe was immobilized onto the PEI-GA film. The coatings were characterized by using atomic force microscopy. Hybridization reaction between probe and the complementary strand was monitored by the QCM system in real-time. This work demonstrated that QCM is a suitable tool for the real-time monitoring of hybridization on the crystal surface without using any label.

Keywords

Piezoelectric Sensor, Alpha-fetoprotein, Quartz Crystal Microbalance, Resonance Frequency, Atomic Force Microscopy, Hybridization, Gene Sensor

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APA
Durkut, S., & Şeker, Ş. (2016). BASED ON QUARTZ CRYSTAL MICROBALANCE. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering, 58(1.2), 9-17. https://doi.org/10.1501/Commub_0000000554
AMA
1.Durkut S, Şeker Ş. BASED ON QUARTZ CRYSTAL MICROBALANCE. Commun. Fac. Sci. Univ. Ank. Ser. B. 2016;58(1.2):9-17. doi:10.1501/Commub_0000000554
Chicago
Durkut, Serap, and Şükran Şeker. 2016. “BASED ON QUARTZ CRYSTAL MICROBALANCE”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 58 (1.2): 9-17. https://doi.org/10.1501/Commub_0000000554.
EndNote
Durkut S, Şeker Ş (June 1, 2016) BASED ON QUARTZ CRYSTAL MICROBALANCE. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 58 1.2 9–17.
IEEE
[1]S. Durkut and Ş. Şeker, “BASED ON QUARTZ CRYSTAL MICROBALANCE”, Commun. Fac. Sci. Univ. Ank. Ser. B, vol. 58, no. 1.2, pp. 9–17, June 2016, doi: 10.1501/Commub_0000000554.
ISNAD
Durkut, Serap - Şeker, Şükran. “BASED ON QUARTZ CRYSTAL MICROBALANCE”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 58/1.2 (June 1, 2016): 9-17. https://doi.org/10.1501/Commub_0000000554.
JAMA
1.Durkut S, Şeker Ş. BASED ON QUARTZ CRYSTAL MICROBALANCE. Commun. Fac. Sci. Univ. Ank. Ser. B. 2016;58:9–17.
MLA
Durkut, Serap, and Şükran Şeker. “BASED ON QUARTZ CRYSTAL MICROBALANCE”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering, vol. 58, no. 1.2, June 2016, pp. 9-17, doi:10.1501/Commub_0000000554.
Vancouver
1.Serap Durkut, Şükran Şeker. BASED ON QUARTZ CRYSTAL MICROBALANCE. Commun. Fac. Sci. Univ. Ank. Ser. B. 2016 Jun. 1;58(1.2):9-17. doi:10.1501/Commub_0000000554