4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST

M. A Metwally

doi:10.1501/Commub_0000000407

EN

4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST

Abstract

Condensation of 4- nitrosopyrazolone (1) with active methylene components namely, malo- nonitrile, acetophenone, co-cyano-acetophenone and / or 1,3- diphenylacetone gave compounds (2a-c) and (4). Treatment of (2a, 2b) with hydrazine hydrate gave the aminopyrazoles (3a, 3b). Reaction of (1) with some lıydrazines afforded derivatives (5, 6, 7a, 7b). While the condensation of (1) with hydrazine hydrate gave the bispyrazolone (8). The structures of the ring systems have been confirmed by their IR, !H-NMR and rnass spectral data.

Keywords

References

4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST

Details

Primary Language

English

Subjects

Chemical Engineering

Journal Section

Research Article

Authors

M. A Metwally This is me
Türkiye

Publication Date

January 1, 1995

Submission Date

January 1, 1995

Acceptance Date

-

Published in Issue

Year 1995 Volume: 41

DOI

https://doi.org/10.1501/Commub_0000000407

IZ

https://izlik.org/JA69ZU53ML

Cite

RIS / Bibtex

APA

Metwally, M. A. (1995). 4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering, 41. https://doi.org/10.1501/Commub_0000000407

AMA

1.Metwally MA. 4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST. Commun. Fac. Sci. Univ. Ank. Ser. B. 1995;41. doi:10.1501/Commub_0000000407

Chicago

Metwally, M. A. 1995. “4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 41 (January). https://doi.org/10.1501/Commub_0000000407.

EndNote

Metwally MA (January 1, 1995) 4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 41

IEEE

[1]M. A. Metwally, “4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST”, Commun. Fac. Sci. Univ. Ank. Ser. B, vol. 41, Jan. 1995, doi: 10.1501/Commub_0000000407.

ISNAD

Metwally, M. A. “4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering 41 (January 1, 1995). https://doi.org/10.1501/Commub_0000000407.

JAMA

1.Metwally MA. 4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST. Commun. Fac. Sci. Univ. Ank. Ser. B. 1995;41. doi:10.1501/Commub_0000000407.

MLA

Metwally, M. A. “4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST”. Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering, vol. 41, Jan. 1995, doi:10.1501/Commub_0000000407.

Vancouver

1.M. A Metwally. 4- NİTROSO -1- PHENYL -3- METHYL -2- PYRAZOLİN -5- ONE IN THE SYNTHESIS OF: SOME NEW 4- SUBSTITUTED HETEOCYCLES OF PHARMACEUTICAL INTEREST. Commun. Fac. Sci. Univ. Ank. Ser. B. 1995 Jan. 1;41. doi:10.1501/Commub_0000000407