A COMPARATIVE STUDY OF ZERO-ORDER AND DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RIVASTIGMINE IN SINGLE DOSAGE FORM
Abstract
In this study zero-order, first and second derivative spectrophotometric methods were applied to the determination of Rivastigmine (RVT) in capsules. UV-spectrum, first derivative and second derivative spectrums of RVT were plotted in the spectral range of 230-280 nm. Zero-order, first derivative and second derivative absorbance values were measured at maximum wavelenghts for this three methods. Lineer calibration graphs were found in the working range of 0.2 mM -1.0 mM (80 - 400 pg ml1). All three methods were statistically compared with each other and significant results were obtained
References
- Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering
Abstract
References
- Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering
Details
| Primary Language | English |
|---|---|
| Subjects | Chemical Engineering |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | January 1, 2004 |
| Published in Issue | Year 2004 Volume: 50 Issue: 01 |
Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering
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