Synthesis of 4-Amino-N-Ethyl-N-P-HydroxyethyIanilin Hemi-Sulfate Hydrate

Year 1968, Volume: 15 , 0 - 0, 01.01.1968

Celâl Tüzün

Abstract

4-Amino-N-ethyl-N-ı8~hydroxyethylaniline hemi-sulfate hydrate was synthesized by nitrosation of N-ethyl-N-p-hydroxyethylaniline, then reduced with zinc powder/ hydrochloric acid, without isolating of the nitroso compound. The amine salt so formed was basified with ammonia, then extracted with chloroform and the free base converted its hemi-sulfate hydrate directly, by adding a sufficient amount of sulfuric acid in ethanol.

Keywords

Synthesis, Hydrate, Hemi-Sulfate

References

• Ankara Üniversitesi Communications, Series B: Chemistry and Chemical Engineering