Research Article

AGE DETERMINATION OF FOSSILS COLLECTED FROM KARABÜK, SAFRANBOLU, BULAK RIVER AREA BY USING AMINO ACID RACEMIZATION METHOD

Volume: 27 Number: 1 June 1, 2018
  • Sibel Kara
  • Tahir Özdemir
  • Ergin Murat Altuner
EN

AGE DETERMINATION OF FOSSILS COLLECTED FROM KARABÜK, SAFRANBOLU, BULAK RIVER AREA BY USING AMINO ACID RACEMIZATION METHOD

Abstract

Amino acids present in the proteins of living organisms are mostly in L forms at the time they are synthesized. Over a very long period of time after the death of living organisms, due to the effect of high temperature, pressure and other environmental factors a chemical transformation of L form to its enantiomer, D form occurs. This conversion reaction is known as racemization and it continues until D/L ratio is equal to 1. Thus, the age of any death body can be predicted by determining the D/L ratio of amino acids. The aim of this study is to determine the age of fossils collected from Karabük, Safranbolu, Bulak River area by using amino acid racemization method. Five fossil samples were used and D/L alanine ratios in the samples were used to determine their ages. As a result of the study it was observed that the age estimations by amino acid racemization method were quite lower than the age predictions during fossil identification step. The reason of this difference is thought to be related to the lack of data in the literature, which is used in constructing calibration curve

Keywords

References

  1. C.A. Challener, Overview of chirality. In: Chiral drugs, 1st. Aldershot (England): Ashgate Publisher, 3-14, 2001.
  2. D.E. Drayer, The early history of stereochemistry. In: Drug stereochemistry, Analytical methods and pharmacology, I.W. Wainer, editor. New York: Marcel Dekker Publisher. 1-24, (1993).
  3. L.A. Nguyen, H. He, and C. Pham-Huy, Chiral drugs: an overview, International Journal of Biomedical Science, 2(2), (2006) 85.
  4. H.B. Vickery, Rules for the nomenclature of the natural amino acids and related substances. Journal of Biological Chemistry, 169(2), (1947) 237-245.
  5. J.L. Bada, Racemization of amino acids. In: Chemistry and biochemistry of the amino acids, Dordrecht: Springer. 399-414, 1985.
  6. B.J. Johnson and G.H. Miller, Archaeological applications of amino acid racemization, Archaeometry. 39(2), (1997) 265-287.
  7. A. Julg, Origin of the L-homochirality of amino-acids in the proteins of living organisms. In: Molecules in Physics, Chemistry, and Biology. Dordrecht: Springer. 33-52, 1989.
  8. J.L. Bada, Amino acid racemization dating of fossil bones, Annual Review of Earth and Planetary Sciences, 13(1), (1985) 241-268.

Details

Primary Language

English

Subjects

Structural Biology

Journal Section

Research Article

Authors

Sibel Kara This is me

Tahir Özdemir This is me

Ergin Murat Altuner This is me

Publication Date

June 1, 2018

Submission Date

May 12, 2014

Acceptance Date

-

Published in Issue

Year 2018 Volume: 27 Number: 1

Communications Faculty of Sciences University of Ankara Series C Biology licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License