ANTIMUTAGENIC AND ANTIOXIDANT ACTIVITIES OF TEUCRIUM MULTICAULE AND ITS CYTOTOXIC EFFECT ON MURINE LR7 CELL

Abstract

In present study, DNA protection, antioxidant and cytotoxic effects of Teucrium multicaule Montbret Et Aucher Ex Bentham methanol extract (TME) was investigated. Cytotoxic effects and antioxidant activities of TME was determined by MTT and DPPH scavenging and DNA protection methods. As a result, high dose of TME exhibited a cytotoxic effect on murine L cells. Although, TME also showed a strong antimutagenic activity in DNA protection test system, it exhibited modest activity in DPPH test system. Consequently, it may be used as natural agent for antioxidant and antimutagenic properties.

Keywords

• Cytotoxicity,DNA protection,Antioxidant,Antimutagenic,Teucrium multicaule

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