LATENT PROTEİN GENE SİTE IN EPSTEIN BARR VİRÜS (EBV) AND ITS DELETION

Abstract

In the present study, samples which were diagnosed as nasopharyngeal carcinoma, larynx carcinoma, Burkitt lympoma, hodgkin and nonhodgkin lympoma were investigated in terms of latent protein gene site in Epstein Barr Virüs (EBV). After DNA isolation frotn those samples, polimerase chain reaction was carried out at LMP (Latent Membrane Protein) gen sequences. Amplified samples were subjected restriction enzyme (Xhol, Msp I) analysis. We were not observed any EBV-Xho-I variants. Heterodoublex formation was determined in one of the hodgkin samples. Deletion was observed at LMP 2 sequence in 11 of the same samples.

Keywords

• present
• EBV-Xho-I
• Burkitt

References

1. Ankara Üniversitesi Communications, Series C: Biology