Production cross-section and reaction yield of 82Sr for 82Sr/82Rb generator
Abstract
There are many radioisotopes used for diagnostic and therapeutic purposes in nuclear medicine. One of the radioisotopes used for diagnostic purposes is 82Rb. It is used in positron emission tomography (PET) as to be positron emitter and commonly obtained from 82Sr/82Rb generator. In this study, we have investigated some possible production mechanisms of 82Sr by regarding 82Sr/82Rb generator. 85,87Rb(p,xn)82Sr and 80,82,83,84,86Kr(3He,xn)82Sr reaction channels have been investigated using the CTFGM, BSFGM, and GSM models within the framework of TALYS nuclear reaction code. It has been seen that the production cross-sections, reaction yields and total activation values calculated up to 60 MeV beam energy value are in agreement with the available data in the literature.
Keywords
Production cross-section, Reaction yield, Strontium-82, Reaction yield, Strontium-82
References
- [1] Gündoğdu E.A., Özgenç E., Ekinci M., Nükleer Tıpta Görüntüleme ve Tedavide Kullanılan Radyofarmasötikler, J Lit Pharm., 7 (1) (2018) 24-34.
- [2] Azaam A., Excitation functions for proton-induced reactions on Te and natTi targets: Measurements and model calculations special relevant to the 128Te(p,n)128I reaction, Nuclear Physics A., 121790 (2020) 999.
- [3] 82Sr Decay scheme, NOS. Available at: https://www.google.com/search?q=sr82+decay+scheme&rlz. Retrieved October 4, 2022.
- [4] Aardenah K., van der Walt T.N., Davids C., Radiochemical separation of 82Sr and preparation of sterile 82Sr/82Rb generator columm, J. Radional Nucl. Chem., 270 (2006) 385-390.
- [5] Hoffman I., Medical isotope production, research reactors and their contribution to the global xenon background, Journal of Radioanalytical and Nuclear Chemistry, 318 (2018) 165-173.
- [6] Phillips D.R., Peterson E.J., Production of strontium-82 for the Cardiogen PET generator: a project of the Department of Energy Virtual Isotope Center, Radiochim. Acta., 88 (2000) 149-155.
- [7] Horiguchi T., Nome H., Yoshizawa Y., Excitation functions of proton-induced nuclear reaction on 85Rb, J. Appl. Rad. Isot., 36 (1980) 141-151.
- [8] Vereshchagin Yu.I., Zagryadskiy V.A., Prusakov V.N., Cyclotron 82Sr production for medical applications, Nuclear Instruments and Methods to Physics Research A., 334 (1993) 246-248.
- [9] Kastleiner S., Qaim S.M., Nortier F., Excitation functions of 85Rb(p,xn)85m,g,83,82,81Sr reactions up to 100 MeV integral test of cross section data, comparison of production routes of 83Sr and thick target yield of 82Sr, Applied Radiation and Isotopes, 56 (2002) 685–695.
- [10] Buthelezi E.Z., Nortier F.M., Schroeder I.W., Excitation functions fort the production of 82Sr by proton bombardment of natRb at energies up to 100 MeV, Applied Radiation and Isotopes, 64 (2006) 915-924.