Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients

Othman R Al Samarraı; Hazem Mohammed Abd; Mohammed Hameed Mahal; Ali Rasheed Hameed Al Samarrai

doi:10.17776/csj.1562338

EN

Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients

Abstract

The goal of this research was to estimate the concentrations of iron and hepcidin with liver and kidney functions in beta-thalassemia patients, the study involved the collection of 80 blood samples from both sexes, and the samples were distributed into 45 samples for beta thalassemia patients, their ages ranged between 15-25 years, the samples were collected from the Thalassemia Specialization Center in Baquba General Hospital, and 35 blood samples for healthy people as a control group, their ages extended from 15 to 25. years, during the period from the beginning of March 2023 until the end of May 2023. The study's findings revealed a considerable increase in the concentrations of hepcidin and iron in patients group compared with the healthy ones. It also displayed a significant reduce in the patients' albumin and creatinine concentrations as compared with healthy group, while the results here were no significant variations in total protein, urea and uric acid levels.

Keywords

Beta-thalassemia, Hepcidin, Iron, Liver, Kidney

References

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Details

Primary Language

English

Subjects

Analytical Biochemistry

Journal Section

Research Article

Authors

Othman R Al Samarraı ^*
0000-0002-1487-4054
Iraq

Hazem Mohammed Abd
0000-0002-8661-2985
Iraq

Mohammed Hameed Mahal
0000-0002-7207-3140
Iraq

Ali Rasheed Hameed Al Samarrai
0000-0001-9963-4449
Iraq

Publication Date

March 25, 2025

Submission Date

October 6, 2024

Acceptance Date

January 22, 2025

Published in Issue

Year 2025 Volume: 46 Number: 1

DOI

https://doi.org/10.17776/csj.1562338

IZ

https://izlik.org/JA65UP86BP

APA

Al Samarraı, O. R., Abd, H. M., Mahal, M. H., & Al Samarrai, A. R. H. (2025). Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients. Cumhuriyet Science Journal, 46(1), 8-12. https://doi.org/10.17776/csj.1562338

AMA

1.Al Samarraı OR, Abd HM, Mahal MH, Al Samarrai ARH. Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients. CSJ. 2025;46(1):8-12. doi:10.17776/csj.1562338

Chicago

Al Samarraı, Othman R, Hazem Mohammed Abd, Mohammed Hameed Mahal, and Ali Rasheed Hameed Al Samarrai. 2025. “Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients”. Cumhuriyet Science Journal 46 (1): 8-12. https://doi.org/10.17776/csj.1562338.

EndNote

Al Samarraı OR, Abd HM, Mahal MH, Al Samarrai ARH (March 1, 2025) Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients. Cumhuriyet Science Journal 46 1 8–12.

IEEE

[1]O. R. Al Samarraı, H. M. Abd, M. H. Mahal, and A. R. H. Al Samarrai, “Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients”, CSJ, vol. 46, no. 1, pp. 8–12, Mar. 2025, doi: 10.17776/csj.1562338.

ISNAD

Al Samarraı, Othman R - Abd, Hazem Mohammed - Mahal, Mohammed Hameed - Al Samarrai, Ali Rasheed Hameed. “Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients”. Cumhuriyet Science Journal 46/1 (March 1, 2025): 8-12. https://doi.org/10.17776/csj.1562338.

JAMA

1.Al Samarraı OR, Abd HM, Mahal MH, Al Samarrai ARH. Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients. CSJ. 2025;46:8–12.

MLA

Al Samarraı, Othman R, et al. “Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients”. Cumhuriyet Science Journal, vol. 46, no. 1, Mar. 2025, pp. 8-12, doi:10.17776/csj.1562338.

Vancouver

1.Othman R Al Samarraı, Hazem Mohammed Abd, Mohammed Hameed Mahal, Ali Rasheed Hameed Al Samarrai. Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients. CSJ. 2025 Mar. 1;46(1):8-12. doi:10.17776/csj.1562338

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Evaluation Of Hepcidin And Iron Concentrations With Liver And Kidney Functions In Beta-Thalassemia Patients

Abstract

Keywords

Abstract

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

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