Electrochemical Behavior of Cholecalciferol on a Multiwalled Carbon Nanotube Modified Glassy Carbon Electrode
Abstract
Herein,
electrochemical behavior of cholecalciferol on a multiwalled carbon nanotube
modified glassy carbon electrode was evaluated by using cyclic voltammetry.
Voltammetric determination of cholecalciferol on the prepared modified
electrode was carried out using linear sweep voltammetry. A good linearity was
obtained with a correlation coefficient of 0.9914 between 5×10-5 – 1×10-3 M. The LOD and LOQ values were
calculated as 1.7×10-5
and 5.1×10-5 M, respectively. The response of the proposed electrode was
sufficiently repeatable for determining cholecalciferol. Finally, the proposed modified
electrode was successfully applied to the determination of cholecalciferol in a
commercial oral solution that contains 300.000 I.U cholecalciferol/mL. A simple
liquid-liquid extraction technique by using methanol was followed to extract cholecalciferol from the oral liquid. The
results obtained with the proposed method were in agreement with
cholecalciferol content of the commercial oral solution.
Keywords
References
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