Research Article
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Year 2019, Volume: 22 Issue: 1, 22 - 30, 13.03.2019
https://doi.org/10.7126/cumudj.432692

Abstract

References

  • 1. Azarpazhooh A, Main PA. Fluoride varnish in the prevention of dental caries in children and adolescents: a systematic review. J Can Dent Assoc. 2008; 74(1):73-9.
  • 2. Kato MT, Leite AL, Hannas AR, Oliveira RC, Pereira JC, Tjäderhane L, Buzalaf MAR. Effect of iron on matrix metalloproteinase inhibition and on the prevention of dentine erosion. Caries Research 2010; 44(3): 309-316.
  • 3. Kumar VL, Itthagarun A, King NM. The effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro study. Aust Dent J 2008; 53: 34-40.
  • 4. Queiroz CS, Hara AT, Paes Leme AF, Cury JA. PH cycling models to evaluate the effect of low fluoride dentifrice on enamel de- and remineralization. Braz Dent J. 2008; 19(1): 21– 7.
  • 5. Peters MC, Bresciani E, Barata TJ, Fagundes TC, Navarro RL, Navarro MF, Dickens SH. In vivo dentin remineralization by calcium-phosphate cement. J Dent Res. 2010; 89 (3): 286-91.
  • 6. Wiegand A, Krieger C, Attin R, Hellwig E, Attin T. Fluoride uptake and resistance to further demineralisation of demineralised enamel after application of differently concentrated acidulated sodium fluoride gels. Clin Oral Investig. 2005;9(1):52-7.
  • 7. Wong MC, Clarkson J, Glenny AM, Lo EC, Marinho VC, Tsang BW, Walsh T, Worthington HV. Cochrane reviews on the benefits/risks of fluoride toothpastes. J Dent Res. 2011; 90(5): 573-9.
  • 8. Passalini P, Fidalgo TK, Caldeira EM, Gleiser R, Nojima da C, Maia LC. Preventive effect of fluoridated orthodontic resins subjected to high cariogenic challenges. Braz Dent J 2010; 21(3): 211-5.
  • 9. White DJ. Reactivity of fluoride dentifrices with artificial caries. I. Effects on early lesions: F uptake, surface hardening and remineralization. Caries Res. 1987; 21:126-40.
  • 10. Poggio C, Grasso N, Ceci M, Beltrami R, Colombo M, Chiesa M. Ultrastructural evaluation of enamel surface morphology after tooth bleaching followed by the application of protective pastes. Scanning. 2016; 38(3): 221-6.
  • 11. Rodrigues E, Botazzo Delbem AC, Pedrini D, Cavassan L. Enamel Remineralization by Fluoride-Releasing Materials: Proposal of a pH-Cycling Model. Braz. Dent. J. 2010; 21(5): 446-51.
  • 12. Salonen J, Arjasmaa M, Tuominen U, Behbehani MJ, Zaatar EI. Bioactive glass in dentistry. J Minimum Interv Dent. 2009; 2: 208-18.
  • 13. Wefel JS. NovaMin: Likely clinical success. Adv Dent Res 2009;21:40-3. 14. Madan N, Madan N, Sharma V, Pardal D. Tooth remineralization using bio active glass-a novel approach. J Aca Adv Dent Res 2011; 2(2): 45-50.
  • 15. Lynch RJ, Mony U, ten Cate JM. Effect of lesion characteristics and mineralizing solution type on enamel remineralization in vitro. Caries Res 2007; 41: 257-62. 16. Vieira AE, Delbem AC, Sassaki KT, Rodrigues E, Cury JA, Cunha RF. Fluoride dose response in pH-cycling models using bovine enamel. Caries Res. 2005; 39(6): 514-20.
  • 17. Meredith P, Donald, AM, and Thiel B. Electron-gas interactions in the environmental SEM's gaseous detector. Scanning. 1996; 18: 467-73.
  • 18. Gelhard TB, Arends J. In vivo remineralization of artificial subsurface lesions in human enamel. I. J Biol Buccale. 1984;12(1): 49-57.
  • 19. Queiroz CS, Hara AT, Paes Leme AF, Cury JA ,pH-Cycling Models to Evaluate the Effect of Low Fluoride Dentifrice on Enamel De- and Remineralization. Braz. Dent. J. 2008; 19(1): 21-7.
  • 20. Wolfgang HA, Dorow A, Langenhorst S, Gintner Z, Bánóczy J, Gaengler P. Effect of fluoride toothpastes on enamel demineralization. BMC Oral Health. 2006; 6: 8.
  • 21. Tschoppe P, Zandim LD, Martus P, Kielbassa MA. Enamel and dentine remineralization by nano-hydroxyapatite toothpastes. J Dent. 2011; 39: 430-37.
  • 22. Aren G. Çocukta floridli diş macunu kullanımının yararları ve olası riskleri. TDBD 2014; 140: 74-9.
  • 23. Madan N, Sharma V, Pardal D, Madan N. Tooth remineralization using bio-active glass - A novel approach. J Acad Adv Dent Res 2011; 2: 45-9.
  • 24. Rao A, Malhotra N. The Role of Remineralizing Agents in Dentistry: A Review. Compendium, 22(6): 26-32, 2011.
  • 25. Palaniswamy UK, Prashar N, Kaushik M, Lakkam SR, Arya S, Pebbeti S. A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion. Dent Res J 2016; 13: 297-302.
  • 26. Mony S, Rao A, Shenoy R, Suprabha BS. Comparative evaluation of the remineralizing efficacy of calcium sodium phosphosilicate agent and fluoride based on quantitative and qualitative analysis. J Indian Soc Pedod Prev Dent 2015; 33: 291-5.
  • 27. Rajan R, Krishnan R, Bhaskaran B, Kumar SV. A Polarized Light Microscopic Study to Comparatively evaluate Four Remineralizing Agents on Enamel viz CPP-ACPF, ReminPro, SHY-NM and Colgate Strong Teeth. Int J Clin Pediatr Dent 2015; 8(1): 42-7.
  • 28. Narayana SS, Deepa VK, Ahamed S, Sathish ES, Meyappan R, Satheesh Kumar KS, Remineralization efficiency of bioactive glass on artificially induced carious lesion an in-vitro study, J. Indian Soc. Pedod. Prev Dent. 2014; 32: 19–25.
  • 29. Golpayegani MV, Biria AM, Ansari G. Remineralization Effect of Topical NovaMin Versus Sodium Fluoride (1.1%) on Caries-Like Lesions in Permanent Teeth. Journal of Dentistry, Tehran University of Medical Sciences 2012; 9(1): 68-75.
  • 30. Mehta AB, Kumari V, Jose R, Izadikhah V. Remineralization potential of bioactive glass and casein phosphopeptide-amorphous calcium phosphate on initial carious lesion: An in-vitro pH-cycling study. J Conserv Dent 2014; 17: 3-7.
  • 31. Wang Y, Mei L, Gong L, Li J, He S, Ji Y, Sun W. Remineralization of early enamel caries lesions using different bioactive elements containing toothpastes: An in vitro study. Technol Health Care 2016; 24(5): 701-11.
  • 32. Diamanti I, Koletsi-Kounari H, Mamai-Homata E, Vougiouklakis G. In vitro evaluation of fluoride and calcium sodium phosphosilicate toothpastes, on root dentine caries lesions journal of dentisty 2011; 39: 619-28.
  • 33. Singhal RK, Balwant R. Remineralization Potential of Three Tooth Pastes on Enamel Caries. Open Access Maced J Med Sci. 2017; 5(5): 664–666.
  • 34. Nakata T, Kitasako Y, Sadr A, Nakashima S, Tagami J. Effect of a calcium phosphate and fluoride paste on prevention of enamel demineralization. Dent Mater J. 2018; 37(1): 65-70.
  • 35. Assunção CM, Goulart M, Essvein TE, Santos NMD, Erhardt MCG, Lussi A, Rodrigues JA. Effect of erosive challenges on deciduous teeth undergoing restorative procedures with different adhesive protocols: an in-vitro study. J Appl Oral Sci. 2018; 26: e20170053. doi: 10.1590/1678-7757-2017-0053.
  • 36. Gutiérrez-Salazara B, Reyes-Gasgaa J. Microhardness and Chemical Composition of Human Tooth. Materials Research 2003; 6(3): 367-73.
  • 37. Bakry AS, Marghalani HY, Amin OA, Tagami J. The effect of a bioglass paste on enamel exposed to erosive challenge, J. Dent. 2014; 42: 1458–63.

Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study

Year 2019, Volume: 22 Issue: 1, 22 - 30, 13.03.2019
https://doi.org/10.7126/cumudj.432692

Abstract

Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization.

Materials and Methods: Twenty-eight sound human enamel samples were randomly divided into four groups (A-D) each having seven samples as follows: A (Novamin), B (1450 ppm NaF and Novamin), C (CPP-ACP), D (1450ppm NaF). After inducing caries-like lesions, each group was maintained daily for demineralization-remineralization cycle for seven days. During this cycle, samples were treated by the selected toothpaste for each group. Enamel mineral loss was assessed by surface microhardness. Surface enamel microhardness was determined on the enamel blocks. Non-parametric Kruskar-Wallis test compares the amount of surface microhardness recovery (SMHR%) across four different toothpastes.

Results: PLM data revealed a mineral precipitation band on the surface layer of all toothpastes; however, when compared to treated lesions, no statistically significant differences among the groups (p>0.05) were found. Conclusions: NovaMin containing dentifrice has similar remineralization potential on carious-like lesions when compared to fluoride containing dentifrices.

References

  • 1. Azarpazhooh A, Main PA. Fluoride varnish in the prevention of dental caries in children and adolescents: a systematic review. J Can Dent Assoc. 2008; 74(1):73-9.
  • 2. Kato MT, Leite AL, Hannas AR, Oliveira RC, Pereira JC, Tjäderhane L, Buzalaf MAR. Effect of iron on matrix metalloproteinase inhibition and on the prevention of dentine erosion. Caries Research 2010; 44(3): 309-316.
  • 3. Kumar VL, Itthagarun A, King NM. The effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro study. Aust Dent J 2008; 53: 34-40.
  • 4. Queiroz CS, Hara AT, Paes Leme AF, Cury JA. PH cycling models to evaluate the effect of low fluoride dentifrice on enamel de- and remineralization. Braz Dent J. 2008; 19(1): 21– 7.
  • 5. Peters MC, Bresciani E, Barata TJ, Fagundes TC, Navarro RL, Navarro MF, Dickens SH. In vivo dentin remineralization by calcium-phosphate cement. J Dent Res. 2010; 89 (3): 286-91.
  • 6. Wiegand A, Krieger C, Attin R, Hellwig E, Attin T. Fluoride uptake and resistance to further demineralisation of demineralised enamel after application of differently concentrated acidulated sodium fluoride gels. Clin Oral Investig. 2005;9(1):52-7.
  • 7. Wong MC, Clarkson J, Glenny AM, Lo EC, Marinho VC, Tsang BW, Walsh T, Worthington HV. Cochrane reviews on the benefits/risks of fluoride toothpastes. J Dent Res. 2011; 90(5): 573-9.
  • 8. Passalini P, Fidalgo TK, Caldeira EM, Gleiser R, Nojima da C, Maia LC. Preventive effect of fluoridated orthodontic resins subjected to high cariogenic challenges. Braz Dent J 2010; 21(3): 211-5.
  • 9. White DJ. Reactivity of fluoride dentifrices with artificial caries. I. Effects on early lesions: F uptake, surface hardening and remineralization. Caries Res. 1987; 21:126-40.
  • 10. Poggio C, Grasso N, Ceci M, Beltrami R, Colombo M, Chiesa M. Ultrastructural evaluation of enamel surface morphology after tooth bleaching followed by the application of protective pastes. Scanning. 2016; 38(3): 221-6.
  • 11. Rodrigues E, Botazzo Delbem AC, Pedrini D, Cavassan L. Enamel Remineralization by Fluoride-Releasing Materials: Proposal of a pH-Cycling Model. Braz. Dent. J. 2010; 21(5): 446-51.
  • 12. Salonen J, Arjasmaa M, Tuominen U, Behbehani MJ, Zaatar EI. Bioactive glass in dentistry. J Minimum Interv Dent. 2009; 2: 208-18.
  • 13. Wefel JS. NovaMin: Likely clinical success. Adv Dent Res 2009;21:40-3. 14. Madan N, Madan N, Sharma V, Pardal D. Tooth remineralization using bio active glass-a novel approach. J Aca Adv Dent Res 2011; 2(2): 45-50.
  • 15. Lynch RJ, Mony U, ten Cate JM. Effect of lesion characteristics and mineralizing solution type on enamel remineralization in vitro. Caries Res 2007; 41: 257-62. 16. Vieira AE, Delbem AC, Sassaki KT, Rodrigues E, Cury JA, Cunha RF. Fluoride dose response in pH-cycling models using bovine enamel. Caries Res. 2005; 39(6): 514-20.
  • 17. Meredith P, Donald, AM, and Thiel B. Electron-gas interactions in the environmental SEM's gaseous detector. Scanning. 1996; 18: 467-73.
  • 18. Gelhard TB, Arends J. In vivo remineralization of artificial subsurface lesions in human enamel. I. J Biol Buccale. 1984;12(1): 49-57.
  • 19. Queiroz CS, Hara AT, Paes Leme AF, Cury JA ,pH-Cycling Models to Evaluate the Effect of Low Fluoride Dentifrice on Enamel De- and Remineralization. Braz. Dent. J. 2008; 19(1): 21-7.
  • 20. Wolfgang HA, Dorow A, Langenhorst S, Gintner Z, Bánóczy J, Gaengler P. Effect of fluoride toothpastes on enamel demineralization. BMC Oral Health. 2006; 6: 8.
  • 21. Tschoppe P, Zandim LD, Martus P, Kielbassa MA. Enamel and dentine remineralization by nano-hydroxyapatite toothpastes. J Dent. 2011; 39: 430-37.
  • 22. Aren G. Çocukta floridli diş macunu kullanımının yararları ve olası riskleri. TDBD 2014; 140: 74-9.
  • 23. Madan N, Sharma V, Pardal D, Madan N. Tooth remineralization using bio-active glass - A novel approach. J Acad Adv Dent Res 2011; 2: 45-9.
  • 24. Rao A, Malhotra N. The Role of Remineralizing Agents in Dentistry: A Review. Compendium, 22(6): 26-32, 2011.
  • 25. Palaniswamy UK, Prashar N, Kaushik M, Lakkam SR, Arya S, Pebbeti S. A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion. Dent Res J 2016; 13: 297-302.
  • 26. Mony S, Rao A, Shenoy R, Suprabha BS. Comparative evaluation of the remineralizing efficacy of calcium sodium phosphosilicate agent and fluoride based on quantitative and qualitative analysis. J Indian Soc Pedod Prev Dent 2015; 33: 291-5.
  • 27. Rajan R, Krishnan R, Bhaskaran B, Kumar SV. A Polarized Light Microscopic Study to Comparatively evaluate Four Remineralizing Agents on Enamel viz CPP-ACPF, ReminPro, SHY-NM and Colgate Strong Teeth. Int J Clin Pediatr Dent 2015; 8(1): 42-7.
  • 28. Narayana SS, Deepa VK, Ahamed S, Sathish ES, Meyappan R, Satheesh Kumar KS, Remineralization efficiency of bioactive glass on artificially induced carious lesion an in-vitro study, J. Indian Soc. Pedod. Prev Dent. 2014; 32: 19–25.
  • 29. Golpayegani MV, Biria AM, Ansari G. Remineralization Effect of Topical NovaMin Versus Sodium Fluoride (1.1%) on Caries-Like Lesions in Permanent Teeth. Journal of Dentistry, Tehran University of Medical Sciences 2012; 9(1): 68-75.
  • 30. Mehta AB, Kumari V, Jose R, Izadikhah V. Remineralization potential of bioactive glass and casein phosphopeptide-amorphous calcium phosphate on initial carious lesion: An in-vitro pH-cycling study. J Conserv Dent 2014; 17: 3-7.
  • 31. Wang Y, Mei L, Gong L, Li J, He S, Ji Y, Sun W. Remineralization of early enamel caries lesions using different bioactive elements containing toothpastes: An in vitro study. Technol Health Care 2016; 24(5): 701-11.
  • 32. Diamanti I, Koletsi-Kounari H, Mamai-Homata E, Vougiouklakis G. In vitro evaluation of fluoride and calcium sodium phosphosilicate toothpastes, on root dentine caries lesions journal of dentisty 2011; 39: 619-28.
  • 33. Singhal RK, Balwant R. Remineralization Potential of Three Tooth Pastes on Enamel Caries. Open Access Maced J Med Sci. 2017; 5(5): 664–666.
  • 34. Nakata T, Kitasako Y, Sadr A, Nakashima S, Tagami J. Effect of a calcium phosphate and fluoride paste on prevention of enamel demineralization. Dent Mater J. 2018; 37(1): 65-70.
  • 35. Assunção CM, Goulart M, Essvein TE, Santos NMD, Erhardt MCG, Lussi A, Rodrigues JA. Effect of erosive challenges on deciduous teeth undergoing restorative procedures with different adhesive protocols: an in-vitro study. J Appl Oral Sci. 2018; 26: e20170053. doi: 10.1590/1678-7757-2017-0053.
  • 36. Gutiérrez-Salazara B, Reyes-Gasgaa J. Microhardness and Chemical Composition of Human Tooth. Materials Research 2003; 6(3): 367-73.
  • 37. Bakry AS, Marghalani HY, Amin OA, Tagami J. The effect of a bioglass paste on enamel exposed to erosive challenge, J. Dent. 2014; 42: 1458–63.
There are 35 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research Articles
Authors

Zerrin Abbasoglu

Damla Aksit Bıçak

Dilara Ozenay Dergin

Didem Kural

İlknur Tanboğa

Publication Date March 13, 2019
Submission Date June 10, 2018
Published in Issue Year 2019Volume: 22 Issue: 1

Cite

EndNote Abbasoglu Z, Aksit Bıçak D, Ozenay Dergin D, Kural D, Tanboğa İ (March 1, 2019) Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study. Cumhuriyet Dental Journal 22 1 22–30.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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