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Year 2015, Volume: 36 Issue: 3, 2317 - 2324, 13.05.2015

Ali Saları , Ghasem Jamalı Mansour Ebrahımı

Abstract

Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools

Year 2015, Volume: 36 Issue: 3, 2317 - 2324, 13.05.2015

Ali Saları , Ghasem Jamalı Mansour Ebrahımı

Abstract

Abstract. Endometrial cancer has two types. In this study we assessed the type 2 by microRNA-200c to find differential genes between the two treatment and control groups and then to find the genes candidate (candidate genes) for microRNA treatment instead of surgery which is the most fundamental treatment in this cancer. By some software’s as GEO2R, 85 types (kinds) of genes with differential expression from control and treatment groups were calculated. Also by DAVID tools, the candidates’ genes function was extracted. For the first time the genes obtained by microarray data were introduced as candidates for diagnose and treatment of Endometrial cancer cells. The most important genes from the 12 candidates up regulated genes. The 4 genes namely PLAC8, AKR1D1, ANXA3, ESYT2 and from the 9 down regulated candidate genes by miR-200c, 3 genes SLC17A3,THEMIS2, L3HYPDH were reported for the first time in this study. The two above mentioned finding are reported for the first .

Keywords

Treatment miR-200c endometrial cancer

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Details

Journal Section Special
Authors

Ali Saları

Ghasem Jamalı This is me

Mansour Ebrahımı This is me

Publication Date May 13, 2015
Published in Issue Year 2015 Volume: 36 Issue: 3

Cite

APA Saları, A., Jamalı, G., & Ebrahımı, M. (2015). Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi, 36(3), 2317-2324.
AMA Saları A, Jamalı G, Ebrahımı M. Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi. May 2015;36(3):2317-2324.
Chicago Saları, Ali, Ghasem Jamalı, and Mansour Ebrahımı. “Use MicroRNA-200c in Endometrial Cancer Treatment With Bioinformatics Tools”. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi 36, no. 3 (May 2015): 2317-24.
EndNote Saları A, Jamalı G, Ebrahımı M (May 1, 2015) Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi 36 3 2317–2324.
IEEE A. Saları, G. Jamalı, and M. Ebrahımı, “Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools”, Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi, vol. 36, no. 3, pp. 2317–2324, 2015.
ISNAD Saları, Ali et al. “Use MicroRNA-200c in Endometrial Cancer Treatment With Bioinformatics Tools”. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi 36/3 (May 2015), 2317-2324.
JAMA Saları A, Jamalı G, Ebrahımı M. Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi. 2015;36:2317–2324.
MLA Saları, Ali et al. “Use MicroRNA-200c in Endometrial Cancer Treatment With Bioinformatics Tools”. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi, vol. 36, no. 3, 2015, pp. 2317-24.
Vancouver Saları A, Jamalı G, Ebrahımı M. Use microRNA-200c in Endometrial Cancer Treatment with Bioinformatics Tools. Cumhuriyet Üniversitesi Fen Edebiyat Fakültesi Fen Bilimleri Dergisi. 2015;36(3):2317-24.