In-vitro antioxidant and in-silico wound healing activity of Quercus infectoria dry extract

Year 2024, , 41 - 47, 06.07.2024

Mohammed Ismail Benlazar , Soumia Merzoug

https://doi.org/10.38093/cupmap.1488652

Abstract

In the present study we were interested in the healing activity of Quercus infectoria gall extract. We started by preparing the extract by two methods. The polyphenol and tannin content was then determined. The antioxidant activity of the extract was evaluated in-vitro using DPPH radical scavenging assay.
The last part of this study concerns the study of the healing activity in silico by molecular docking assisted by the Shrödinger program and this via the inhibition of GSK3-β, an enzyme involved among others in the healing process.

Keywords

Quercus infectoria, tannins, healing activity, antioxidant activity, molecular docking, GSK3-β.

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