Detection and Quantification of Preservatives in Green Cosmetics
Abstract
Abstract
Preservatives are used in cosmetic formulations to provide protection against microbial growth to ensure the safety and the quality during their shelf life. Benzyl alcohol, sodium benzoate and sorbic acid are the preservatives that can be used in green cosmetic formulations. According to the cosmetic legislation usage of above indicated preservatives are restricted and thus determination and quantification of them from the cosmetic products have become important. In this study analytical methods are given to enable the determination of benzyl alcohol, sodium benzoate and sorbic acid. The methods are based on extracting the preservative agents from four different pharmaceutical form (solution, emulsion, gel and cream) of the various cosmetic matrices and later on detection in the scope of the basic chromatographic data and test parameters by High Performance Liquid Chromatography (HPLC) system with UV Detector.
Keywords
References
- Nair B., Final Report On The Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate, Int J Toxicol., 2001, 20 (3):23-50.DOI:10.1080/10915810152630729
- http://www.titck.gov.tr/Mevzuat
- http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_073.pdf
- https://ec.europa.eu/health/sites/health/files/endocrine_disruptors/docs/cosmetic_1223_2009_regulation_en.pdf
- Nogal Sánchez M., Pérez-Pavón J.L., Moreno Cordero B. Determination of Suspected Allergens in Cosmetic Products by Head Space-Programmed Temperatur Evaporization-Fast Gas Chromatography-Quadrupole Mass Spectrometry, Anal Bioanal Chem., 2010, 397(6), 2579-91.doi: 10.1007/s00216-010-3803-8.
- Baranowska I., Wojciechowska I. The Determination of Preservatives in Cosmetics and Environmental Waters by HPLC, Pol. J. Environ. Stud., 2013, 22(6),1609-25.
- Baranowska I., Wojciechowska I. Determination of Preservatives in Cosmetics, Cleaning Agents and Pharmaceuticals Using Fast Liquid Chromatography Journal of Chromatographic Science, 2014, 52(1,1),88–94. DOI: 10.1093/chromsci/bms210
- Concise International Chemical Assessment Document 26 Benzoic Acid and Sodium Benzoate, World Health Organization, 2000, http://www.who.int/ipcs/publications/cicad/cicad26_rev_1.pdf
Details
Primary Language
English
Subjects
-
Journal Section
Research Article
Authors
Nilay Civil
This is me
0000-0003-1475-6258
Türkiye
Ebru Üncüoğlu
This is me
0000-0002-5508-3232
Türkiye
Publication Date
December 31, 2018
Submission Date
December 4, 2018
Acceptance Date
December 26, 2018
Published in Issue
Year 2018 Volume: 1 Number: 2
Cited By
Benzoic acid treated Drosophila melanogaster: the genetic disruption of larval brain stem cells and non-neural cells during metamorphosis
Toxicology and Environmental Health Sciences
https://doi.org/10.1007/s13530-021-00082-w







CUPMAP Journal is licensed under a