Year 2018, Volume 1 , Issue 1, Pages 8 - 12 2018-07-28



Sideritis öztürkii (Lamiaceae) Aytac & Aksoy is an endemic species to Turkey and used as herbal tea and folk medicine in Central Anatolia.  The purpose of this study is to reveal the apoptotic effects of different extracts derived from S. öztürkii on DLD-1 colorectal cancer cell line via Real Time PCR technique. By this aim, the expression levels of apoptotic genes for each extract were determined via Real Time PCR and then the expression levels were evaluated and compared respectively. Especially, leaf methanol extract was found to be more effective than leaf aqueous extract in terms of apoptosis induction. The results infer that the ironwort extracts have different effects on pro and anti-apoptotic gene expression levels. In conclusion, the leaf and flower extracts have apoptosis inducing activity in the different levels on DLD-1 cell line. 

DLD-1, endemic, Turkey
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Primary Language en
Subjects Science
Journal Section First Issue

Author: Ela Nur ŞİMŞEK SEZER (Primary Author)
Country: Turkey

Country: Turkey


Publication Date : July 28, 2018

APA ŞİMŞEK SEZER, E , UYSAL, T . (2018). THE EFFECTS OF THE SIDERITIS OZTURKII EXTRACT ON THE EXPRESSION LEVELS OF SOME APOPTOTIC GENES. Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) , 1 (1) , 8-12 . Retrieved from