Research Article
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Year 2020, Volume: 3 Issue: 1, 1 - 7, 27.06.2020
https://doi.org/10.38093/cupmap.692879

Abstract

References

  • 1. Azami, L., Babapour, A., Garechahi, M., 2012. Antimicrobial Effect of aqueous extract of saffron petals on some of food-borne bacterial pathogen. Food Hygiene, 2(1 (5)):63-73.
  • 2. Catoni, C., Schaefer, H.M. and Peters, A., 2008. Fruit for health: the effect of flavonoids on humoral immune response and food selection in a frugivorous bird. Functional Ecology, 649-654.
  • 3. Digrak, M., Alma, M.H. and Ilçim, A., 2001. Antibacterial and antifungal activities of Turkish medicinal plants. Pharmaceutical Biology, 39(5):346-350.
  • 4. Gandomi Nasrabadi, H., Azami Sarokelaei, L., Misaghi, A., Abbaszadeh, S., Shariatifar, N. and Tayyar Hashtjin, N., 2012. Antibacterial effect of aqueous and alcoholic extracts from petal of saffron (Crocus sativus L.) on some foodborne bacterial pathogens. Journal of Medicinal Plants, 2(42);189-196.
  • 5. Gezici, S. Comparative anticancer activity analysis of saffron extracts and a principle component, crocetin for prevention and treatment of human malignancies. 2019. Journal of Food Science and Technology, 56(12); 5435-5443.
  • 6. Gupta, V.K., Fatima, A., Faridi, U., Negi, A.S., Shanker, K., Kumar, J.K., Rahuja, N., Luqman, S., Sisodia, B.S., Saikia, D. and Darokar, M.P., 2008. Antimicrobial potential of Glycyrrhiza glabra roots. Journal of ethnopharmacology, 116(2): 377-380.
  • 7. Hemmati Kakhki, A. and Rahimi, S.K., 1994. Extraction of anthocyanin from petals of saffron (Crocus sativus L.) and its stability in a model beverage. Iran. Res. Org. Sci. Technol.
  • 8. Hepsø, H.U., Bjørnland, T. and Skoglund, L.A., 1988. Side-effects and patient acceptance of 0.2% versus 0.1% chlorhexidine used as postoperative prophylactic mouthwash. International journal of oral and maxillofacial surgery, 17(1):17-20.
  • 9. Islam, M.J., Barua, S., Das, S., Khan, M.S. and Ahmad, A., 2008. Antibacterial activity of some indigenous medicinal plants. Journal of Soil of Nature, 2(3):26-28.
  • 10. Jafari-Sales, A., Jafari, B., Sayyahi, J. and Zohoori-Bonab, T., 2015. Evaluation of antibacterial activity of ethanolic extract of malva neglecta and althaea officinalis l. On antibiotic-resistant strains of staphylococcus aureus. J Biol Today World, 4(2):58-62.
  • 11. Jafari-Sales, A., Mobaiyen, H., Jafari, B. and Sayyahi, J., 2019a. Assessment of Antibacterial Effect of Alcoholic Extract of Centaurea depressa MB, Reseda lutea L. and Fumaria asepala on Selected Standard Strains in Vitro. Scientific Journal of Nursing, Midwifery and Paramedical Faculty, 5(3):63-73.
  • 12. Jafari-Sales, A., Rasi-Bonab, F. and Sayyahi, J., 2019b. The Survey on Antimicrobial Effects of Methanolic Extract of Carum Copticum L. on Staphylococcus Aureus, Bacillus Cereus, Escherichia Coli and Pseudomonas Aeruginosa in Laboratory Conditions. Paramedical Sciences and Military Health, 13(4):19-25.
  • 13. Kandil, O., Radwan, N.M., Hassan, A.B., Amer, A.M.M., El-Banna, H.A. and Amer, W.M.M., 1994. Extracts and fractions of Thymus capitatus exhibit antimicrobial activities. Journal of ethnopharmacology, 44(1):19-24.
  • 14. Mirheidar, H., 2005. Maaref giahi (Plant Knowledge). Tehran, Iran, Daftare Nashre Farhange Eslami, 172-173.
  • 15. Mobaiyen, H., Jafari Sales, A. and Sayyahi, J., 2016. Evaluating antimicrobial effects of centaurea plant’s essential oil on pathogenic bacteria: staphylococcus aureus, staphylococcus epidermidis, and escherichia coli isolated from clinical specimens. Journal of Fasa University of Medical Sciences, 5(4):479-487.
  • 16. Motamedi, H., Darabpour, E., Gholipour, M. and Seyyednejad, S.M., 2010. Antibacterial effect of ethanolic and methanolic extracts of Plantago ovata and Oliveria decumbens endemic in Iran against some pathogenic bacteria. Int J Pharmacol, 6(2):117-122.
  • 17. Ordog, V., Stirk, W.A., Lenobel, R., Bancířová, M., Strnad, M., Van Staden, J., Szigeti, J. and Németh, L., 2004. Screening microalgae for some potentially useful agricultural and pharmaceutical secondary metabolites. Journal of applied phycology, 16(4):309-314.
  • 18. Pintado, C., de Miguel, A., Acevedo, O., Nozal, L., Novella, J.L. and Rotger, R., 2011. Bactericidal effect of saffron (Crocus sativus L.) on Salmonella enterica during storage. Food Control, 22(3-4):638-642.
  • 19. Poma, A., Fontecchio, G., Carlucci, G. and Chichiricco, G., 2012. Anti-inflammatory properties of drugs from saffron crocus. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Inflammatory and Anti-Allergy Agents), 11(1):37-51.
  • 20. Razaghi, R., 2003. Investigation of antibacterial compounds of saffron stigma. In Third National Conference on Saffran, Iran.
  • 21. Sales, A.J., 2014. Evaluation of antibacterial activity of ethanol extract of Lavandula Stoechas L. plant on antibiotic-resistant strains Of Staphylococcus Aureus. Journal of Current Research in Science, 2(6):641.
  • 22. Sales, A.J., Bagherizadeh, Y., Malekzadeh, P., et al., 2017. Evaluation of the Antimicrobial Effects of Essential Oil of Reseda Lutea L. on Pathogenic Bacteria: Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia Coli. Arch Clin Microbiol, 8:3.
  • 23. Sales, A.J., Shadbad, N.N. and Kaleybar, V.P., 2015. The Investigation of the Antibacterial effects of Ethanol extract of Cichorium intybus L. on Antibiotic-resistant Staphylococcus aureus strains. Bull Env Pharmacol Life Sci, 4:161-4.
  • 24. Singh, J., Kumar, A., Budhiraja, S. and Hooda, A., 2007. Ethnomedicine: use in dental caries. Brazilian Journal of Oral Sciences, 6(21):1308-1312.
  • 25. Skaltsa, H.D., Lazari, D.M., Chinou, I.B. and Loukis, A.E., 1999. Composition and antibacterial activity of the essential oils of Stachys candida and S. chrysantha from southern Greece. Planta medica, 65(03):255-256.
  • 26. Tajalli, F., 2008. Two methods to determine antioxidant properties of saffron petals DPPH and linoleic acid model system. The National Congress of Food Science and Technology, Iran.
  • 27. Tang, W. and Eisenbrand, G., 2013. Chinese drugs of plant origin: chemistry, pharmacology, and use in traditional and modern medicine. Springer Science & Business Media, 395-8.
  • 28. Tayel, A.A. and El-Tras, W.F., 2009. Possibility of fighting food borne bacteria by Egyptian folk medicinal herbs and spices extracts. J Egypt Public Health Assoc, 84(1-2):21-32.
  • 29. Vahidi, H., Kamalinejad, M. and Sedaghati, N., 2010. Antimicrobial properties of Croccus sativus L. Iranian Journal of Pharmaceutical Research, 1:33-35.
  • 30. VandenBergh, M.F., Yzerman, E.P., van Belkum, A., Boelens, H.A., Sijmons, M. and Verbrugh, H.A., 1999. Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state. Journal of clinical microbiology, 37(10):3133-3140.
  • 31. Zhang, X., Li, Y., Li, B., Mao, Y., Wu, X., Zou, X., Gao, P., Yan, H., Yang, D., Ling, Y. and Chen, H., 2016. Three supplementary methods for analyzing cytotoxicity of Escherichia coli O157: H7. Journal of microbiological methods, 120:34-40.

Antibacterial Effect of Methanolic Extract of Saffron Petal (Crocus sativus L.) on Some Standard Gram Positive and Gram Negative Pathogenic Bacteria In vitro

Year 2020, Volume: 3 Issue: 1, 1 - 7, 27.06.2020
https://doi.org/10.38093/cupmap.692879

Abstract

Background: Nowadays, increasing antibiotic resistance of bacteria has provided the
opportunity to replace herbal remedies with fewer side effects than
conventional medicines; therefore, in this study, the antibacterial effects of
methanolic extract of saffron petal against Staphylococcus
aureus
, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli strains were evaluated.
Materials and Methods: In this in
vitro study, after collecting the saffron plant and confirming its scientific
name, the saffron petal extract was prepared in concentrations of 20 mg/ml to
400 mg/ml. Then the antimicrobial effects of this extract were investigated by
well diffusion and tube dilution method. 
Results: The results showed
that the methanolic extract of saffron petal had antibacterial effects on the
tested bacteria in both tube dilution and well diffusion methods. The highest
effect was observed in S. aureus and
the least in P. aeruginosa.  Conclusion:
Based on the above results, it can be hoped that Saffron petals extract can be used
in the treatment of bacterial infections and can be a suitable replacement for
conventional chemical drugs in the treatment of infections.

References

  • 1. Azami, L., Babapour, A., Garechahi, M., 2012. Antimicrobial Effect of aqueous extract of saffron petals on some of food-borne bacterial pathogen. Food Hygiene, 2(1 (5)):63-73.
  • 2. Catoni, C., Schaefer, H.M. and Peters, A., 2008. Fruit for health: the effect of flavonoids on humoral immune response and food selection in a frugivorous bird. Functional Ecology, 649-654.
  • 3. Digrak, M., Alma, M.H. and Ilçim, A., 2001. Antibacterial and antifungal activities of Turkish medicinal plants. Pharmaceutical Biology, 39(5):346-350.
  • 4. Gandomi Nasrabadi, H., Azami Sarokelaei, L., Misaghi, A., Abbaszadeh, S., Shariatifar, N. and Tayyar Hashtjin, N., 2012. Antibacterial effect of aqueous and alcoholic extracts from petal of saffron (Crocus sativus L.) on some foodborne bacterial pathogens. Journal of Medicinal Plants, 2(42);189-196.
  • 5. Gezici, S. Comparative anticancer activity analysis of saffron extracts and a principle component, crocetin for prevention and treatment of human malignancies. 2019. Journal of Food Science and Technology, 56(12); 5435-5443.
  • 6. Gupta, V.K., Fatima, A., Faridi, U., Negi, A.S., Shanker, K., Kumar, J.K., Rahuja, N., Luqman, S., Sisodia, B.S., Saikia, D. and Darokar, M.P., 2008. Antimicrobial potential of Glycyrrhiza glabra roots. Journal of ethnopharmacology, 116(2): 377-380.
  • 7. Hemmati Kakhki, A. and Rahimi, S.K., 1994. Extraction of anthocyanin from petals of saffron (Crocus sativus L.) and its stability in a model beverage. Iran. Res. Org. Sci. Technol.
  • 8. Hepsø, H.U., Bjørnland, T. and Skoglund, L.A., 1988. Side-effects and patient acceptance of 0.2% versus 0.1% chlorhexidine used as postoperative prophylactic mouthwash. International journal of oral and maxillofacial surgery, 17(1):17-20.
  • 9. Islam, M.J., Barua, S., Das, S., Khan, M.S. and Ahmad, A., 2008. Antibacterial activity of some indigenous medicinal plants. Journal of Soil of Nature, 2(3):26-28.
  • 10. Jafari-Sales, A., Jafari, B., Sayyahi, J. and Zohoori-Bonab, T., 2015. Evaluation of antibacterial activity of ethanolic extract of malva neglecta and althaea officinalis l. On antibiotic-resistant strains of staphylococcus aureus. J Biol Today World, 4(2):58-62.
  • 11. Jafari-Sales, A., Mobaiyen, H., Jafari, B. and Sayyahi, J., 2019a. Assessment of Antibacterial Effect of Alcoholic Extract of Centaurea depressa MB, Reseda lutea L. and Fumaria asepala on Selected Standard Strains in Vitro. Scientific Journal of Nursing, Midwifery and Paramedical Faculty, 5(3):63-73.
  • 12. Jafari-Sales, A., Rasi-Bonab, F. and Sayyahi, J., 2019b. The Survey on Antimicrobial Effects of Methanolic Extract of Carum Copticum L. on Staphylococcus Aureus, Bacillus Cereus, Escherichia Coli and Pseudomonas Aeruginosa in Laboratory Conditions. Paramedical Sciences and Military Health, 13(4):19-25.
  • 13. Kandil, O., Radwan, N.M., Hassan, A.B., Amer, A.M.M., El-Banna, H.A. and Amer, W.M.M., 1994. Extracts and fractions of Thymus capitatus exhibit antimicrobial activities. Journal of ethnopharmacology, 44(1):19-24.
  • 14. Mirheidar, H., 2005. Maaref giahi (Plant Knowledge). Tehran, Iran, Daftare Nashre Farhange Eslami, 172-173.
  • 15. Mobaiyen, H., Jafari Sales, A. and Sayyahi, J., 2016. Evaluating antimicrobial effects of centaurea plant’s essential oil on pathogenic bacteria: staphylococcus aureus, staphylococcus epidermidis, and escherichia coli isolated from clinical specimens. Journal of Fasa University of Medical Sciences, 5(4):479-487.
  • 16. Motamedi, H., Darabpour, E., Gholipour, M. and Seyyednejad, S.M., 2010. Antibacterial effect of ethanolic and methanolic extracts of Plantago ovata and Oliveria decumbens endemic in Iran against some pathogenic bacteria. Int J Pharmacol, 6(2):117-122.
  • 17. Ordog, V., Stirk, W.A., Lenobel, R., Bancířová, M., Strnad, M., Van Staden, J., Szigeti, J. and Németh, L., 2004. Screening microalgae for some potentially useful agricultural and pharmaceutical secondary metabolites. Journal of applied phycology, 16(4):309-314.
  • 18. Pintado, C., de Miguel, A., Acevedo, O., Nozal, L., Novella, J.L. and Rotger, R., 2011. Bactericidal effect of saffron (Crocus sativus L.) on Salmonella enterica during storage. Food Control, 22(3-4):638-642.
  • 19. Poma, A., Fontecchio, G., Carlucci, G. and Chichiricco, G., 2012. Anti-inflammatory properties of drugs from saffron crocus. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Inflammatory and Anti-Allergy Agents), 11(1):37-51.
  • 20. Razaghi, R., 2003. Investigation of antibacterial compounds of saffron stigma. In Third National Conference on Saffran, Iran.
  • 21. Sales, A.J., 2014. Evaluation of antibacterial activity of ethanol extract of Lavandula Stoechas L. plant on antibiotic-resistant strains Of Staphylococcus Aureus. Journal of Current Research in Science, 2(6):641.
  • 22. Sales, A.J., Bagherizadeh, Y., Malekzadeh, P., et al., 2017. Evaluation of the Antimicrobial Effects of Essential Oil of Reseda Lutea L. on Pathogenic Bacteria: Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia Coli. Arch Clin Microbiol, 8:3.
  • 23. Sales, A.J., Shadbad, N.N. and Kaleybar, V.P., 2015. The Investigation of the Antibacterial effects of Ethanol extract of Cichorium intybus L. on Antibiotic-resistant Staphylococcus aureus strains. Bull Env Pharmacol Life Sci, 4:161-4.
  • 24. Singh, J., Kumar, A., Budhiraja, S. and Hooda, A., 2007. Ethnomedicine: use in dental caries. Brazilian Journal of Oral Sciences, 6(21):1308-1312.
  • 25. Skaltsa, H.D., Lazari, D.M., Chinou, I.B. and Loukis, A.E., 1999. Composition and antibacterial activity of the essential oils of Stachys candida and S. chrysantha from southern Greece. Planta medica, 65(03):255-256.
  • 26. Tajalli, F., 2008. Two methods to determine antioxidant properties of saffron petals DPPH and linoleic acid model system. The National Congress of Food Science and Technology, Iran.
  • 27. Tang, W. and Eisenbrand, G., 2013. Chinese drugs of plant origin: chemistry, pharmacology, and use in traditional and modern medicine. Springer Science & Business Media, 395-8.
  • 28. Tayel, A.A. and El-Tras, W.F., 2009. Possibility of fighting food borne bacteria by Egyptian folk medicinal herbs and spices extracts. J Egypt Public Health Assoc, 84(1-2):21-32.
  • 29. Vahidi, H., Kamalinejad, M. and Sedaghati, N., 2010. Antimicrobial properties of Croccus sativus L. Iranian Journal of Pharmaceutical Research, 1:33-35.
  • 30. VandenBergh, M.F., Yzerman, E.P., van Belkum, A., Boelens, H.A., Sijmons, M. and Verbrugh, H.A., 1999. Follow-up of Staphylococcus aureus nasal carriage after 8 years: redefining the persistent carrier state. Journal of clinical microbiology, 37(10):3133-3140.
  • 31. Zhang, X., Li, Y., Li, B., Mao, Y., Wu, X., Zou, X., Gao, P., Yan, H., Yang, D., Ling, Y. and Chen, H., 2016. Three supplementary methods for analyzing cytotoxicity of Escherichia coli O157: H7. Journal of microbiological methods, 120:34-40.
There are 31 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Research Articles
Authors

Abolfazl Jafarı-sales 0000-0002-5710-4076

Mehrdad Pashazadeh This is me 0000-0001-9103-6276

Publication Date June 27, 2020
Published in Issue Year 2020 Volume: 3 Issue: 1

Cite

APA Jafarı-sales, A., & Pashazadeh, M. (2020). Antibacterial Effect of Methanolic Extract of Saffron Petal (Crocus sativus L.) on Some Standard Gram Positive and Gram Negative Pathogenic Bacteria In vitro. Current Perspectives on Medicinal and Aromatic Plants, 3(1), 1-7. https://doi.org/10.38093/cupmap.692879

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