Year 2020, Volume 3 , Issue 2, Pages 128 - 134 2020-12-24

Pistacia terebinthus L., or turpentine tree, is a perennial flowering plant in the Mediterranean region, some aphids species induce the formation of galls in Pistacia terebinthus formerly called Carobs of Judea whose tannin content equals 60%, used in traditional medicine as a stimulant, diuretic, astringent for the treatment of asthma and other respiratory and urological affections, In the present study, the antimitotic activity of Pistacia terebinthus galls was evaluated using meristematic cells of Allium cepa roots assay our results reveal that The methanolic extract decreased the root length and dividing cell number significantly after 96h and compared to control (p< 0.05) the mitotic index of extract at the concentration 4 mg/ml was 31% and has significant activity near to the standard methotrexate Overall, the methanol extract of P. terebinthus galls revealed the presence of the phytochemical’s compounds such as gallic acid, caffeoylquinic acid, which affect plant mitosis and can be used as an antimitotic drug.
Antimitotic, galle, cafeoyllquinic acid, Pistacia terebinthus
  • 1) NAZIM, B., HOUARI, T., & ISMAIL, B. Ethnobotanical Survey of Some Plants Used in Tessala Region, Algeria. Current Perspectives on Medicinal and Aromatic Plants (CUPMAP), 3(1), 18-24. 2) The Daphne Traditional Use and Biological Activities SA Bellifa Nazim, Benhaddou A, Toumi H, Achouri Y Eurasian Congress on Molecular Biotechnology, Trabzon, Turkey.2019 1 (978 …
Primary Language en
Subjects Pharmacology and Pharmacy
Journal Section Research Articles

Orcid: 0000-0002-4247-1850
Author: Bellifa NAZIM (Primary Author)
Institution: University Djilali Liabes SIDI BEL ABBES
Country: Algeria

Orcid: 0000-0002-6322-5907
Author: Benhaddou ISMAIL
Institution: university Djilali Liabes
Country: Algeria

Orcid: 0000-0000-0000-0000
Author: Toumi HOUARİ
Institution: LRDP
Country: Algeria

Orcid: 0000-0002-6922-3865
Author: Noredine ZAKARİA
Institution: University of Tlemcen
Country: Algeria

Supporting Institution University Djilali Liabes UDL SIDI BEL ABBES
Project Number UDL p7/2020
Thanks The authors thank Pr Toumi, Dr Benouala for his assistance and all the members of pharmacognosy Laboratory. Thanks, are also due to Pr Diego cortes , Pr Alvarez R for there contribution and assistance.

Publication Date : December 24, 2020

APA Nazım, B , Ismaıl, B , Houari̇, T , Zakari̇a, N . (2020). In vitro Antimitotic Activity of Gall Extract of Pistacia terebinthus . Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) , 3 (2) , 128-134 . DOI: 10.38093/cupmap.830383