Ankilozan Spondilit Hastalarında Nöropatik Ağrı Sıklığı

This article was retracted on December 31, 2024. https://dergipark.org.tr/en/pub/cusbed/article/1562738

Abstract

Ankilozan Spondilit(AS) kronik inflamatuvar sık görülen bir romatolojik hastalıktır. Romatolojik hastalıklarda inflamatuvar ağrının yanı sıra nöropatik ağrının da arttığı bilinmektedir. Biz çalışmamızda klinik pratikte sıkça karşılaştığımız AS hastalarında nöropatik ağrı varlığını araştırmayı amaçladık. Çalışmaya 52 AS hastası dahil edildi. Çalışmaya dahil edilen kişilerin HLA-B27 genetik test sonucu, c-reaktif protein, eritrosit sedimentasyon hızı değerleri kaydedildi. Tüm katılımcılara nöropatik ağrıyı belirlemek için LANSS ağrı skalası, hastalık aktivitesini değerlendirmek için Bath Ankilozan Spondilit Hastalık Aktivite İndeksi(BASDAİ) uygulandı. Çalışmaya katılan bireylerin yaş ortalaması 42.57’di. LANSS ağrı skalası sonuçlarına göre bireylerin 24’ünde(%46.2) nöropatik ağrı tespit edildi. BASDAİ sonuçlarına göre hastaların %61.5’i aktif hastalığa sahipti. Aktif hastalık ile nöropatik ağrı arasında istatistiksel olarak anlamlı bir ilişki saptandı(p=0.001). AS hastalarında büyük oranda nöropatik ağrının kliniğe eşlik edebileceği sonucuna varıldı. Bu hastalarda nöropatik şikayetlerin ayrıntılı sorgulanmasının ve gerekirse tedavi edilmesinin hastaların yaşam kalitesine olumlu yönde katkı yapacağı ve bir kısmı çok da objektif olarak değerlendirilemeyen hastalık aktivite ölçeklerinin düzeylerinde azalma görülerek aşırı anti-inflamatuvar tedavinin de engellenebileceği kanaatindeyiz.

Keywords

• Ankilozan Spondilit
• nöropatik ağrı
• hastalık aktivitesi

Frequency of Neuropathic Pain in Ankylosing Spondylitis Patients

This article was retracted on December 31, 2024. https://dergipark.org.tr/en/pub/cusbed/article/1562738

Abstract

Ankylosing Spondylitis(AS) is a common chronic inflammatory rheumatological disease. It is known that neuropathic pain, as well as inflammatory pain, increases in rheumatic diseases. In our study, we aimed to investigate the presence of neuropathic pain in AS patients, which we frequently encounter in clinical practice. 52 AS patients were included in the study. HLA-B27 genetic test results, c-reactive protein, and erythrocyte sedimentation rate values of the people included in the study were recorded. LANSS pain scale was applied to all participants to determine neuropathic pain, and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was applied to evaluate disease activity. The average age of the individuals participating in the study was 42.57. According to the results of the LANSS pain scale, neuropathic pain was detected in 24 (46.2%) of the individuals. According to BASDAI results, 61.5% of the patients had active disease. A statistically significant relationship was detected between active disease and neuropathic pain (p = 0.001). It was concluded that neuropathic pain may accompany the clinic in a large proportion of patients with AS. We believe that detailed questioning of neuropathic complaints in these patients and treatment if necessary will contribute positively to the quality of life of the patients, and excessive anti-inflammatory treatment can be prevented by reducing the levels of disease activity scales, some of which cannot be evaluated very objectively.

Keywords

• Ankylosing Spondylitis
• neuropathic pain
• disease activity

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