Does the frequency of diabetes increase in Covid-19 patients? cross-sectional study

Year 2022, Volume: 2 Issue: 3, 61 - 64, 29.07.2022

İhsan Solmaz , Songül Araç

https://doi.org/10.56016/dahudermj.1146367

Abstract

Objective: The aim of this study was to investigate frequency of diabetes mellitus (DM) in patients diagnosed with Covid-19 and whether Covid-19 had effect on high HbA1c.
Material-Methods: Data of DM patients with Covid-19 were analyzed cross-sectionally. In Covid-19, the effect of DM patient frequency and mortality was investigated.
Results: 2057 patients diagnosed with Covid-19 were included in the study. Among these patients, total 192 patients (9.25%) were treated with the diagnosis of DM. 73 (41 males-32 females) were newly diagnosed with DM (38.02%). 119 patients (48 males and 71 females) were previously diagnosed with DM. Eight of DM patients died. Among all Covid-19 in patients followed up, 90 patients died. Mortality of DM patients was not statistically significant compared to mortality of all patients (p=1.000 x=0). Of the patients who were followed up with diagnosis of DM, whose HbA1c were observed in the last 3 months, 16 of 20 patients had increase in HbA1c, and 4 patients had decrease in HbA1c. The mean increase was 1.05.
Conclusion: The frequency of new diagnosis DM in patients with Covid-19 was found to be quite high. There was increase in HbA1c in Covid-19 patients, and Covid-19 was thought to affect the pancreas.

Keywords

Covid-19, Diabetes Mellitus, HbA1c, ARDS, PCR

References

• Covid-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) [Available from: https://coronavirus.jhu.edu/map.html.
• Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 Feb 15;395(10223):507–13.
• Singh AK, Gupta R, Ghosh A, Misra A. Diabetes in Covid-19: prevalence, pathophysiology, prognosis and practical considerations. Diabetes Metab Syndr 2020;14(4):303-10.
• Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA 2020;323(16):1574-81.
• Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A, et al. Clinical characteristics of Covid-19 in New York city. N Engl J Med 2020)
• Docherty AB, Harrison EM, Green CA, et al. Features of 16,749 hospitalised UK patients with Covid-19 using the ISARIC WHO Clinical Characterisation Protocol. medRxiv. 2020.https://www.medrxiv.org/content/10.1101/2020.04.23.20076042v1. Accessed 16 May 2020.
• Jaeckel E, Manns M, Herrath M (2006) Viruses and diabetes. Ann N Y Acad Sci 958:7–25
• Wan J, Sun W, Li X, Ying W, Dai J, Kuai X et al (2006) Infammation inhibitors were remarkably up-regulated in plasma of severe acute respiratory syndrome patients at progressive phase. Proteomics 6:2886–2894