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A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN

Year 2017, Volume: 1 Issue: 1, 32 - 35, 28.12.2017

Abstract



Acral erythema
is a cutaneous reaction that is frequently caused by chemotherapy agents.
Bullous acral erythema is a rare variation of this condition and the reported
cases in the literature are related mostly to cytarabine and methotrexate. A
50-year-old male patient presented to our dermatology outpatient clinic with
painful lesions of the hands and feet that is present for five days. In his
medical history, there was an operation with the diagnosis of right testicular
seminoma two years ago and history of taking bleomycin chemotherapy due to a
recurrence two months ago. There were painful erythematous plaques and bullae
on palmoplantar areas in dermatologic examination. When bullae were drained
with a sterile injector, the content is detected to be serous-hemorrhagic
fluid. With the current anamnesis and clinical findings the patient was
diagnosed to have bullous acral erythema and topical Triticum vulgare extract
therapy was started. Acral erythema is a common dermatosis secondary to
chemotherapeutic agents and bullous acral erythema is a rare variant. Bullous
acral erythema related to bleomycin is rarely reported in the literature, while
methotrexate and cytarabine are the frequently accused agents
.



References

  • 1. Podjasek JO, Camilleri MJ. Bullous acral erythema. An additional consideration in the differential diagnosis of pauci-inflammatory subepidermal bullae. J Cutan Pathol. 2012;39:382-390.
  • 2. Feizy V, Namazi MR, Barikbin BB, Ehsani A. Methotrexate induced acral erythema with bullous reaction. Dermatol Online J. 2003;9:14.
  • 3. Ozmen S, Dogru M, Bozkurt C, Kocaoglu AC. Probable cytarabine induced acral erythema:report of 2 pediatric cases. J Pediatr Hematol Oncol. 2013;35:11-13.
  • 4. Richards KN, Ivan D, Rashid RM, Chon SY. Paclitaxel induced acral erythema. Arch Dermatol. 2012;148:1333-1334.
  • 5. Azurdia RM, Clark RE, Friedmann PS. Chemotherapy induced acral erythema with bullous reaction. Clin Exp Dermatol. 1999;24:64-66.
  • 6. Tezer H, Kuskonmaz B, Kara A et al. Intravenous immunglubulin in the treatment of severe methotrexate induced acral erythema. J Pediatr Hematol Oncol. 2008;30:391-393.
Year 2017, Volume: 1 Issue: 1, 32 - 35, 28.12.2017

Abstract

References

  • 1. Podjasek JO, Camilleri MJ. Bullous acral erythema. An additional consideration in the differential diagnosis of pauci-inflammatory subepidermal bullae. J Cutan Pathol. 2012;39:382-390.
  • 2. Feizy V, Namazi MR, Barikbin BB, Ehsani A. Methotrexate induced acral erythema with bullous reaction. Dermatol Online J. 2003;9:14.
  • 3. Ozmen S, Dogru M, Bozkurt C, Kocaoglu AC. Probable cytarabine induced acral erythema:report of 2 pediatric cases. J Pediatr Hematol Oncol. 2013;35:11-13.
  • 4. Richards KN, Ivan D, Rashid RM, Chon SY. Paclitaxel induced acral erythema. Arch Dermatol. 2012;148:1333-1334.
  • 5. Azurdia RM, Clark RE, Friedmann PS. Chemotherapy induced acral erythema with bullous reaction. Clin Exp Dermatol. 1999;24:64-66.
  • 6. Tezer H, Kuskonmaz B, Kara A et al. Intravenous immunglubulin in the treatment of severe methotrexate induced acral erythema. J Pediatr Hematol Oncol. 2008;30:391-393.
There are 6 citations in total.

Details

Journal Section Case Reports
Authors

Aslı Tatlıparmak This is me

Berna Aksoy This is me

Erol Koç This is me

Publication Date December 28, 2017
Published in Issue Year 2017 Volume: 1 Issue: 1

Cite

APA Tatlıparmak, A., Aksoy, B., & Koç, E. (2017). A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN. DOD Clinical Case Reports, 1(1), 32-35.
AMA Tatlıparmak A, Aksoy B, Koç E. A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN. DODCR. December 2017;1(1):32-35.
Chicago Tatlıparmak, Aslı, Berna Aksoy, and Erol Koç. “A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN”. DOD Clinical Case Reports 1, no. 1 (December 2017): 32-35.
EndNote Tatlıparmak A, Aksoy B, Koç E (December 1, 2017) A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN. DOD Clinical Case Reports 1 1 32–35.
IEEE A. Tatlıparmak, B. Aksoy, and E. Koç, “A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN”, DODCR, vol. 1, no. 1, pp. 32–35, 2017.
ISNAD Tatlıparmak, Aslı et al. “A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN”. DOD Clinical Case Reports 1/1 (December 2017), 32-35.
JAMA Tatlıparmak A, Aksoy B, Koç E. A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN. DODCR. 2017;1:32–35.
MLA Tatlıparmak, Aslı et al. “A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN”. DOD Clinical Case Reports, vol. 1, no. 1, 2017, pp. 32-35.
Vancouver Tatlıparmak A, Aksoy B, Koç E. A CASE OF BULLOUS ACRAL ERYTHEMA DUE TO BLEOMYCIN. DODCR. 2017;1(1):32-5.