Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer

Fatma Seher Delek

Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer

Abstract

A kind of cancer affecting millions of men globally is prostate cancer (PCa). The way that PCa is treated is always changing because of new insights into human genetics and biological processes. A number of novel therapeutic classes have emerged in recent times, such as bone-targeted medications, poly(ADP-ribose) polymerase (PARP) inhibitors, and next-generation androgen receptor (AR) signaling inhibitors. Additionally, PSMA-targeting drugs show promise as theranostics that might enhance the precision of diagnosis and effectiveness of treatment. The outcome of prostate cancer is significantly influenced by the AR signaling pathway. This study examines novel molecules that are either now targeted or may be targeted in the AR signaling pathway, which is highly successful in the carcinogenesis of prostate cancer. Prostate cancer, androgen receptor signaling pathway, therapeutic targets.

Keywords

Prostate cancer, androgen receptor signaling pathway, therapeutic targets.

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Details

Primary Language

English

Subjects

Clinical Oncology

Journal Section

Review

Authors

Fatma Seher Delek
0009-0004-2520-0743
Türkiye

Publication Date

March 12, 2025

Submission Date

October 4, 2024

Acceptance Date

December 2, 2024

Published in Issue

Year 2025 Volume: 39 Number: 1

IZ

https://izlik.org/JA84KS74CA

Cite

RIS / Bibtex

APA

Delek, F. S. (2025). Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer. Developments and Experiments in Health and Medicine, 39(1), 73-88. https://izlik.org/JA84KS74CA

AMA

1.Delek FS. Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer. Dev Exp Health Med. 2025;39(1):73-88. https://izlik.org/JA84KS74CA

Chicago

Delek, Fatma Seher. 2025. “Androgen Receptor Signalling Pathway and Possible Therapeutic Targets ın Prostate Cancer”. Developments and Experiments in Health and Medicine 39 (1): 73-88. https://izlik.org/JA84KS74CA.

EndNote

Delek FS (March 1, 2025) Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer. Developments and Experiments in Health and Medicine 39 1 73–88.

IEEE

[1]F. S. Delek, “Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer”, Dev Exp Health Med, vol. 39, no. 1, pp. 73–88, Mar. 2025, [Online]. Available: https://izlik.org/JA84KS74CA

ISNAD

Delek, Fatma Seher. “Androgen Receptor Signalling Pathway and Possible Therapeutic Targets ın Prostate Cancer”. Developments and Experiments in Health and Medicine 39/1 (March 1, 2025): 73-88. https://izlik.org/JA84KS74CA.

JAMA

1.Delek FS. Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer. Dev Exp Health Med. 2025;39:73–88.

MLA

Delek, Fatma Seher. “Androgen Receptor Signalling Pathway and Possible Therapeutic Targets ın Prostate Cancer”. Developments and Experiments in Health and Medicine, vol. 39, no. 1, Mar. 2025, pp. 73-88, https://izlik.org/JA84KS74CA.

Vancouver

1.Fatma Seher Delek. Androgen receptor signalling pathway and possible therapeutic targets ın prostate cancer. Dev Exp Health Med [Internet]. 2025 Mar. 1;39(1):73-88. Available from: https://izlik.org/JA84KS74CA