Review of carcinogenesis mechanisms and new therapeutic targets in colorectal cancer

Year 2025, Volume: 39 Issue: 3, 207 - 233, 25.07.2025

Ayşenur Başar Önol

https://doi.org/10.18614/dehm.1751154

Abstract

ABSTRACT
Colorectal cancer (CRC) is the third most common cancer among women and men worldwide. The risk of developing CRC is influenced by both environmental and genetic factors. It is known that more than one carcinogenesis mechanism occurs sequentially in some cancers, especially colorectal cancer. In this review, it is planned to present the altered signaling pathways specific to colorectal carcinogenesis and related mechanisms of carcinogenesis and to reveal possible new treatment targets.

Keywords

Colorectal cancer , multistep carcinogenesis

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