In this article, Ibn Qutayba's work named Taʾwīl Mushkil al-Qurʾān is discussed from the perspective of the defense of the Qurʾān. The subject is rather related to the post-nuzūl period. In fact, the issues that make up the content of the work have begun to be dealt with in a scattered way in various works since the Qurʾān was turned into a mushaf. Ibn Qutayba made the related knowledge more compact; he blended it with the prominent topics of the period he lived. In its current form, the work reflects the understanding of tafsīr of the period in one way, and forms the backbone of the works that will be shaped as ʿulūm al-Qurʾān or tafsīr method in the next periods, on the other hand. Therefore, although the issues as discussed have undergone some content and classification changes, from the beginning until today, they are actually the ʿulūm al-Qurʾān in one aspect and the defense of the Qurʾān in another aspect. Therefore, in the article, it is emphasized that the relevant work should be approached with the content of the ʿulūm al-Qurʾān rather than the " tafsīr" book, which is coded in minds today. In the study, firstly the ʿulūm al-Qurʾān dimension of the issue was pointed out, and then the approach of Ibn Qutayba to the subjects was tried to be analyzed in terms of Qurʾānic defense. In the article, the period in which Ibn Qutayba lived and the other works he wrote were taken into account, and his work named Taʾwīl Mushkil al-Qurʾān was taken as a basis.