The Effect of Polypharmacy on Fall Risk, Cognitive Status, Activities of Daily Living, and Mobility in Elderly Residents

Year 2023, , 133 - 140, 06.09.2023

Bülent Abut Özsezikli , Gizem Ergezen

https://doi.org/10.18614/deutip.1272175

Abstract

Objective: The aim of this study is to examine the polypharmacy status of elderly people staying in nursing homes and to investigate the effects of polypharmacy on fall risk, cognition, activities of daily living (ADL), mobility and peripheral muscle strength.
Material and Method: Thirty-nine volunteer elderly individuals aged 65-80 years, staying in a nursing home and having a mini-mental test score above 24, were included in the study. After the age, gender, and drug types of the individuals were noted, evaluations were made for cognition, activities of daily living, risk of falling, mobility and peripheral muscle strength. Individuals using 5 or more drugs were assigned to the polypharmacy group (PFG)(n=21); Those who used 0-3 drugs were included in the non-polypharmacy group (N-PFG)(n=19).
Results: The groups were similar in terms of age and gender (p>0.05). Individuals in the polypharmacy group had significantly lower ADL and mobility than the non-polypharmacy group (p<0.05). There was no difference between the groups in terms of cognition, fall risk and peripheral muscle strength (p>0.05).
Conclusion: As a result, it was observed that only ADL and mobility of those who use multiple drugs are lower than those who do not use them. There was no effect of multi-drug use on cognition, fall risk, and peripheral muscle strength between the groups. In future studies, it is recommended to analyze according to the duration of drug use and to include more objective tests on balance.

Keywords

Multiple Drug Use, Fall Risk, Activity of Daily Living, Mobility, Polypharmacy

Polifarmasinin Huzurevinde Kalan Yaşlı Bireylerde Düşme Riski, Kognitif Durum, Günlük Yaşam Aktiviteleri ve Mobilite Üzerine Etkisi

Abstract

Amaç: Bu çalışmanın amacı, huzurevinde konaklayan yaşlı bireylerin polifarmasi durumunu incelemek ve polifarmasinin düşme riski, kognisyon, günlük yaşam aktiviteleri (GYA), mobilite ve periferik kas kuvvetine olan etkisini araştırmayı amaçlamaktadır.
Gereç ve Yöntem: Çalışmaya 65-80 yaş aralığında huzur evinde konaklayan, mini menmtal test skoru 24’ün üzerinde olan 39 gönüllü yaşlı birey dahil edildi. Bireylerin yaş, cinsiyet ve kullandıkları ilaç tipleri not edildikten sonra kognisyon, günlük yaşam aktivitesi, düşme riski, mobilite ve periferik kas kuvvetine yönelik değerlendirmeler yapıldı. Bireylerden 5 ve üzeri ilaç kullananlar polifarmasi grubuna (PFG)(n=21); 0-3 ilaç kullananlar ise non-polifarmasi grubuna (N-PFG)(n=19) alındı.
Bulgular: Gruplar yaş ve cinsiyet açısından benzerdi (p>0.05). Polifarmasi grubundaki bireylerde GYA ve mobilite non-polifarmasi grubundan anlamlı olarak daha düşüktü (p<0.05). Kognisyon, düşme riski ve periferik kas kuvveti açısından gruplar arasında farklılık bulunmamaktaydı (p>0.05).
Sonuç: Sonuç olarak, çoklu ilaç kullananların kullanmayanlara göre yalnızca GYA ve mobilitelerinin daha düşük olduğu görülmüştür. Çoklu ilaç kullanımının kognisyon, düşme riski ve periferik kas kuvveti üzerine gruplar arasında bir etkisi bulunmamıştır. İleriki çalışmalarda ilaç kullanım sürelerine göre analiz yapılması ve denge ile ilgili daha objektif testlemelerin dahil edilmesi önerilmektedir.

Keywords

Çoklu İlaç Kullanımı, Düşme Riski, Günlük Yaşam Aktivitesi, Mobilite, Polifarmasi

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