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Epidermoid Cysts Of The Testis: A Report Of Three Cases

Year 2017, Volume: 30 Issue: 3, 149 - 153, 13.01.2017

Abstract


Testicular epidermoid cyst is a rare entity that accounts for
approximately 1-2 % of all intratesticular tumors. Although the histogenesis of
the lesion is not clear, its biological behaviour is benign. It is seen
frequently in right testis and on the 2nd and 4th decades. It has to be
distinguished from teratomas and dermoid cysts and due to the malignant
potential of teratomas, this differential diagnosis has a significant value. Mass
lesions of left testis were found in three cases; ultrasonography findings and
tumor markers lead to preoperative diagnosis of testicular tumor and
subsequently, orchiectomy was performed. At the histopathological
investigation, the cysts lined by keratinized squamous epithelium overlying
dense fibrous tissue were observed and diagnosis as epidermoid cyst. Epidermoid
cyst of testis, being as a rare entity, is presented and discussed by means of
literature.

References

  • Referans1 Malek RS, Rosen JS, Farrow GM. Epidermoid cyst of the testis: A critical analysis. Br J Urol 1986;58:55-9.
  • Referans2 Shah KH, Maxted WC, Chun B. Epidermoid cysts of the testis: a report of three cases and an analysis of 141 cases from the world literature. Cancer 1981;47:577-82.
  • Referans3 Heidenreich A, Engelmann UH, Vietsch HV, Derschum W. Organ preserving surgery in testicular epidermoid cysts. J Urol 1995;153:1147-50.
  • Referans4 Cittadini G, Gauglio C, Pretolesi F, Santacroce E, Derchi LE. Bilateral epidermoid cysts of the testis: sonogrophic and MRI findings. J Clin Ultrasound 2004;3:370-2.
  • Referans5 Walsh C, Rushton HG. Diagnosis and management of teratomas and epidermoid cysts. Urol Clin North Am 2000;27:509-18.
  • Referans6 Gupta SK, Golash A, Thomas JA, Cochlin D, Griffiths D, Jenkins BJ. Epidermoid cysts of the testis: the case for conservative surgery. Ann R Coll Surg Engl 2000;82:411-3.
  • Referans7 Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol 2005;18(suppl 2):S61-S79.
  • Referans8 Price EB. Epidermoid cysts of the testis: a clinical and pathological analysis of 69 cases from the testicular tumor registry. J Urol 1969;102:708-13.
  • Referans9 Dieckmann KP, Loy V. Epidermoid cyst of the testis: a review of clinical and histogenetic considerations. Br J Urol 1994;73:436-41.
  • Referans10 Mansfield JT, Cartwright PC. Bilateral testis tumors in an infant: Synchronous teratoma and epidermoid cyst. J Urol 1995;158(3 Pt 2):1077-9.
  • Referans11 Davi RC, Braslis GK, Perez JL. Bilateral epidermoid cyst of the testis. Eur Urol 1996;29:122-4.
  • Referans12 Klein EA. Tumour markers in testis cancer. Urol Clin North Am 1993;20:67-73.
  • Referans13 Bhatt S, Jafri SZH, Wasserman N, Dogra VS. Imaging of non-neoplastic intratesticular masses. Diagn Interv Radiol 2011;17:52-63.
  • Referans14 Dogra VS, Gottlieb RH, Rubens DJ, Oka M, Di Sant Agnese AP. Testicular epidermoid cysts: sonographic features with histopathologic correlation. J Clin Ultrasound 2001;29:192-6.
  • Referans15 Öztürk M, Mavili E, Erdoğan N, Demirci D. Epidermoid cyst of the testicle: unusual magnetic resonance imaging findings. Acta Radiologica 2004;45:882-4.
  • Referans16 Berner A, Franzen S, Heilo A. Fine needle aspiration (FNA) cytology in diagnosis of epidermoid cyst in testis. Cytopathology 1998;9:126-9. Referans17 Perez-Guillermo M, Garcia-Solano J, Sánchez-Sánchez Cet al. Diagnostic limitations in testicular cytopathology: To what extent is fine-needle aspiration reliable for the diagnosis of epidermoid cyst of the testis? Diagn Cytopathol 2004;31:83-6.
  • Referans18 Younger C, Ulbright TM, Zhang S. Molecular evidence supporting the neoplastic nature of some epidermoid cysts of the testis. Arch Pathol Lab Med 2003;127:858-60.
  • Referans19 Cheng L, Zhang S, Maclennan GT, Poulos CK, Sung MT. İnterphase fluorescence in situ hybridization analysis of chromosome 12p abnormalities is useful for distinguishing epidermoid cysts of the testis from pure mature teratoma. Clin Cancer Res 2006;12:5668-72.
  • Referans20 Steiner H, Höltl L, Maneschg C. Frozen section analysis-guide organ-sparing approach in testicular tumors:technique, feasibility, and long-term results. Urology 2003;62:508-13.
  • Referans21 Passman C, Urban D, Klemm K, Lockhart M, Kenney P, Kolettis P. Testicular lesions other than germ cell tumours: feasibility of testis-sparing surgery. BJU Int 2009;103:488-91.
  • Referans22 Parlaktaş BS, Köseoğlu RD, Uluocak N, Erdemir F. Testis sparing surgery for epidermoid cyst of testis in an infertitile man. Erciyes Tıp Dergisi 2005;27:75-7.
  • Referans23 Reinberg Y, Manivel JC, Lerena J. Epidermoid cyst (monodermal teratoma) of the testis. Br J Urol 1990;66:648-51.
  • Referans24 Chiong E, Tan KB, Siew E, Rajwanshi A, Esuvaranathan K. Uncommon benign intrascrotal tumours. Ann Acad Med Singapore 2004;33:351-5.

Testisin Epidermoid Kisti: Üç Olgu Sunumu

Year 2017, Volume: 30 Issue: 3, 149 - 153, 13.01.2017

Abstract

Testiküler epidermoid kist nadir görülür ve intratestiküler tümörler içinde yaklaşık olarak % 1-2 oranındadır. Histogenezi tartışmalı olmakla birlikte; benign biyolojik davranışa sahiptir. En çok 2.-4. dekadlarda ve sağ testiste izlenir. Ayırıcı tanıya teratom ve dermoid kist alınmalıdır. Özellikle teratomlardaki malignite potansiyeli nedeniyle bu ayrım oldukça önemlidir. Üç olgumuzda sol testiste lokalize kitlesel lezyon tespit edilmiş; ultrasonografi bulguları ve tümör belirleyicileri eşliğinde testis tümörü ön tanısı ile orşiektomi uygulanmıştı. Histolopatolojik incelemede fibröz duvara sahip keratinize skuamöz epitel ile döşeli kistler izlendi. Olgular bu bulgular eşliğinde epidermoid kist tanısı aldı. Nadir görülen testisin epidermoid kistleri literatür bilgileri ışığında sunuldu ve tartışıldı.

References

  • Referans1 Malek RS, Rosen JS, Farrow GM. Epidermoid cyst of the testis: A critical analysis. Br J Urol 1986;58:55-9.
  • Referans2 Shah KH, Maxted WC, Chun B. Epidermoid cysts of the testis: a report of three cases and an analysis of 141 cases from the world literature. Cancer 1981;47:577-82.
  • Referans3 Heidenreich A, Engelmann UH, Vietsch HV, Derschum W. Organ preserving surgery in testicular epidermoid cysts. J Urol 1995;153:1147-50.
  • Referans4 Cittadini G, Gauglio C, Pretolesi F, Santacroce E, Derchi LE. Bilateral epidermoid cysts of the testis: sonogrophic and MRI findings. J Clin Ultrasound 2004;3:370-2.
  • Referans5 Walsh C, Rushton HG. Diagnosis and management of teratomas and epidermoid cysts. Urol Clin North Am 2000;27:509-18.
  • Referans6 Gupta SK, Golash A, Thomas JA, Cochlin D, Griffiths D, Jenkins BJ. Epidermoid cysts of the testis: the case for conservative surgery. Ann R Coll Surg Engl 2000;82:411-3.
  • Referans7 Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol 2005;18(suppl 2):S61-S79.
  • Referans8 Price EB. Epidermoid cysts of the testis: a clinical and pathological analysis of 69 cases from the testicular tumor registry. J Urol 1969;102:708-13.
  • Referans9 Dieckmann KP, Loy V. Epidermoid cyst of the testis: a review of clinical and histogenetic considerations. Br J Urol 1994;73:436-41.
  • Referans10 Mansfield JT, Cartwright PC. Bilateral testis tumors in an infant: Synchronous teratoma and epidermoid cyst. J Urol 1995;158(3 Pt 2):1077-9.
  • Referans11 Davi RC, Braslis GK, Perez JL. Bilateral epidermoid cyst of the testis. Eur Urol 1996;29:122-4.
  • Referans12 Klein EA. Tumour markers in testis cancer. Urol Clin North Am 1993;20:67-73.
  • Referans13 Bhatt S, Jafri SZH, Wasserman N, Dogra VS. Imaging of non-neoplastic intratesticular masses. Diagn Interv Radiol 2011;17:52-63.
  • Referans14 Dogra VS, Gottlieb RH, Rubens DJ, Oka M, Di Sant Agnese AP. Testicular epidermoid cysts: sonographic features with histopathologic correlation. J Clin Ultrasound 2001;29:192-6.
  • Referans15 Öztürk M, Mavili E, Erdoğan N, Demirci D. Epidermoid cyst of the testicle: unusual magnetic resonance imaging findings. Acta Radiologica 2004;45:882-4.
  • Referans16 Berner A, Franzen S, Heilo A. Fine needle aspiration (FNA) cytology in diagnosis of epidermoid cyst in testis. Cytopathology 1998;9:126-9. Referans17 Perez-Guillermo M, Garcia-Solano J, Sánchez-Sánchez Cet al. Diagnostic limitations in testicular cytopathology: To what extent is fine-needle aspiration reliable for the diagnosis of epidermoid cyst of the testis? Diagn Cytopathol 2004;31:83-6.
  • Referans18 Younger C, Ulbright TM, Zhang S. Molecular evidence supporting the neoplastic nature of some epidermoid cysts of the testis. Arch Pathol Lab Med 2003;127:858-60.
  • Referans19 Cheng L, Zhang S, Maclennan GT, Poulos CK, Sung MT. İnterphase fluorescence in situ hybridization analysis of chromosome 12p abnormalities is useful for distinguishing epidermoid cysts of the testis from pure mature teratoma. Clin Cancer Res 2006;12:5668-72.
  • Referans20 Steiner H, Höltl L, Maneschg C. Frozen section analysis-guide organ-sparing approach in testicular tumors:technique, feasibility, and long-term results. Urology 2003;62:508-13.
  • Referans21 Passman C, Urban D, Klemm K, Lockhart M, Kenney P, Kolettis P. Testicular lesions other than germ cell tumours: feasibility of testis-sparing surgery. BJU Int 2009;103:488-91.
  • Referans22 Parlaktaş BS, Köseoğlu RD, Uluocak N, Erdemir F. Testis sparing surgery for epidermoid cyst of testis in an infertitile man. Erciyes Tıp Dergisi 2005;27:75-7.
  • Referans23 Reinberg Y, Manivel JC, Lerena J. Epidermoid cyst (monodermal teratoma) of the testis. Br J Urol 1990;66:648-51.
  • Referans24 Chiong E, Tan KB, Siew E, Rajwanshi A, Esuvaranathan K. Uncommon benign intrascrotal tumours. Ann Acad Med Singapore 2004;33:351-5.
There are 23 citations in total.

Details

Journal Section Articles
Authors

Selma Şengiz Erhan

Sevinç Hallaç Keser This is me

Aylin Ege Gül This is me

Şükran Kayıpmaz This is me

Publication Date January 13, 2017
Submission Date July 29, 2015
Published in Issue Year 2017 Volume: 30 Issue: 3

Cite

Vancouver Şengiz Erhan S, Hallaç Keser S, Ege Gül A, Kayıpmaz Ş. Testisin Epidermoid Kisti: Üç Olgu Sunumu. DEU Tıp Derg. 2017;30(3):149-53.