Nicolau Syndrome After Intramuscular Clindamycin Injection

Year 2019, Volume: 33 Issue: 3, 257 - 260, 06.02.2020

Erhan Aygün Yakup Yeşil Mehmet Keleşoğlu

https://doi.org/10.5505/deutfd.2019.96658

Abstract

Nicolau syndrome is a rare complication of intramuscular injections caused by various drugs that presents with severe pain at the injection site. It is characterized by local aseptic necrosis, skin necrosis, and rarely, muscle necrosis on the injection site. Although it may rarely occur after intramuscular injection of anti-inflammatory drugs, corticosteroids, local anesthetics, penicillin and interferon, in our literature search we encountered no cases of Nicolau syndrome after clindamycin injections. Herein, we report a case of Nicolau sydrome that occurred after intramuscular clindamycin injection in the right-middle thigh because of its rarity.

Keywords

Nicolau Syndrome, clindamycin, intramuscular injection

İNTRAMUSKÜLER KLİNDAMİSİN ENJEKSİYONU SONRASI NICOLAU SENDROMU

Abstract

Nikolau sendromu, enjeksiyon bölgesinde şiddetli ağrı ile ortaya çıkan çeşitli ilaçların neden olduğu kas içi enjeksiyonların nadir görülen bir komplikasyonudur. Lokal aseptik nekroz, cilt nekrozu ve nadiren enjeksiyon bölgesinde kas nekrozu ile karakterizedir. Antienflamatuar ilaçların, kortikosteroidlerin, lokal anesteziklerin, penisilin ve interferonun intramüsküler enjeksiyonundan sonra nadiren görülebilmesine rağmen, literatür araştırmamızda klindamisin enjeksiyonlarından sonra hiçbir Nikolau sendromu vakasıyla karşılaşılmadı. Bu yazıda, sağ orta uylukta intramüsküler klindamisin enjeksiyonu sonrası meydana gelen bir Nikolau sendromu olgusu sunuldu.

Keywords

Nikolau Sendromu, klindamisin, intramüsküler enjeksiyon

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