Oral complications in diabetes mellitus
Year 2025,
Volume: 26 Issue: 1, 11 - 14, 28.03.2025
Bedriye İbiş
,
Müzeyyen Kandemir
,
Ela Tules Kadiroğlu
Abstract
Diabetes mellitus is a chronic metabolic disorder characterised by high blood glucose levels that can lead to various systemic complications. Among these complications, oral complications play an important role due to the high vascularisation and innervation of the oral cavity. Regular dental examinations, effective oral hygiene practices and treatments to regulate blood glucose levels are the main methods that contribute to the effective management of complications. Understanding the relationship between diabetes mellitus and oral health and implementing preventive strategies are crucial to improve the overall health and quality of life of individuals with diabetes mellitus. The aim of this review is to provide an overview of these oral complications and the problems they cause.
References
- American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2006;29(Suppl 1):S43-S48.
- Păunică I, Giurgiu M, Dumitriu AS, et al. The bidirectional relationship between periodontal disease and diabetes mellitus-a review. Diagnostics (Basel). 2023;13(4):681. doi:10.3390/diagnostics13040681
- Vlachou S, Loumé A, Giannopoulou C, Papathanasiou E, Zekeridou A. Investigating the interplay: periodontal disease and type 1 diabetes mellitus-a comprehensive review of clinical studies. Int J Mol Sci. 2024; 25(13):7299. doi:10.3390/ijms25137299
- Çorakçı A, Kaya A, Tuzcu A, et al. Diyabet tanı ve tedavi rehberi. Türkiye Diyabet Vakfı. 2023.
- American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2013;36(Suppl 1):S67-S74. doi:10.2337/dc13-S067
- Newman MG, Carranza FA, Takei HH, Klokkevold PR. Carranza’s clinical periodontology. Elsevier Brasil. 2006.
- Mauri-Obradors E, Estrugo-Devesa A, Jané-Salas E, Viñas M, López-López J. Oral manifestations of diabetes mellitus. A systematic review. Med Oral Patol Oral Cir Bucal. 2017;22(5):e586-e594. doi:10.4317/medoral. 21655
- Smiljka C, Irena M, Jelena K, Dragan I, Nikola S. Oral alterations in diabetes mellitus. Balkan J Dent Med. 2018;22(3):7-14. doi:10.2478/bjdm-2018-0002
- Lamster IB. Diabetes and oral health-current concepts regarding periodontal disease and dental caries. US Endocrinol. 2012;8(2):93. doi: 10.17925/use.2012.08.02.93
- Khan T. Oral manifestations and complications of diabetes mellitus: a review. Int J Med Health Res. 2018;4:50-52.
- Al-Maskari AY, Al-Maskari MY, Al-Sudairy S. Oral manifestations and complications of diabetes mellitus: a review. Sultan Qaboos Univ Med J. 2011;11(2):179-186.
- Rohani B. Oral manifestations in patients with diabetes mellitus. World J Diabetes. 2019;10(9):485-489. doi:10.4239/wjd.v10.i9.485
- Tsujimoto T, Imai K, Kanda S, Kakei M, Kajio H, Sugiyama T. Sweet taste disorder and vascular complications in patients with abnormal glucose tolerance. Int J Cardiol. 2016;221:637-641. doi:10.1016/j.ijcard. 2016.07.062
- Balamanikandan P, Shetty P, Shetty UA. Diabetic tongue-a review. Romanian J Diabet Nutrit Metabol Dis. 2021;28(2):218-222. doi:10.46389/rjd-2021-1033
- Abiko Y, Selimovic D. The mechanism of protracted wound healing on oral mucosa in diabetes: a review. Bosnian J Basic Med Sci. 2010;10(3): 186-191. doi:10.17305/bjbms.2010.2683
- Eke PI, Borgnakke WS, Genco RJ. Recent epidemiologic trends in periodontitis in the USA. Periodontology. 2019;82(1):257-267. doi:10. 1111/prd.12323
- Parihar AS, Gopinath S, Rathi M, Jalaluddin M, Khatavkar PR, Laddha R. Diabetes and oral health: advancements in prevention, screening and treatment of periodontal diseases. J Pharm Bioallied Sci. 2024;16(Suppl 3): S1968-S1970. doi:10.4103/jpbs.jpbs_469_24
- Deheriya M, Bhargava A, Pippal D, Ahirwar A. Assessment of periodontal status in adults with diabetes mellitus. Int J Res Med Sci. 2020;8(11):3891. doi:10.18203/2320-6012.ijrms20204430
- Kim EK, Lee SG, Choi YH, et al. Association between diabetes-related factors and clinical periodontal parameters in type-2 diabetes mellitus. BMC Oral Health. 2013;13:64. doi:10.1186/1472-6831-13-64
- Jepsen S, Caton JG, Albandar JM, et al. Periodontal manifestations of systemic diseases and developmental and acquired conditions: consensus report of workgroup 3 of the 2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions. J Clin Periodontol. 2018;45(Suppl 20):S219-S229. doi:10.1111/jcpe.12951
- Borgnakke WS. IDF diabetes atlas: diabetes and oral health-a two-way relationship of clinical importance. Diabetes Res Clin Pract. 2019;157: 107839. doi:10.1016/j.diabres.2019.107839
- Teles F, Wang Y, Hajishengallis G, Hasturk H, Marchesan JT. Impact of systemic factors in shaping the periodontal microbiome. Periodontol 2000. 2021;85(1):126-160. doi:10.1111/prd.12356