DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER

Nezahat Nurefşan Evli; Simin Kocaaydın

doi:10.21306/dishekimligi.1581695

Review

CURRENT ADVANCES DENTIN BONDING AGENTS

Year 2025, Volume: 11 Issue: 1, 1 - 10, 27.03.2025

Nezahat Nurefşan Evli , Simin Kocaaydın

https://doi.org/10.21306/dishekimligi.1581695

Abstract

Adhesion is a critical process in restorative dentistry, establishing a strong bond between mineralized tooth tissues and restorative materials. Dentin bonding agents are defined as thin resin layers that enhance this bonding. In clinical practice, various generations of bonding agents have been developed to reduce treatment time, facilitate application, and improve restoration durability. These adhesive systems yield more effective outcomes in restorative treatments and continue to be refined with the goal of preserving tooth tissue. This review examines the definition and importance of adhesion, along with the history, classifications, and comparisons of dentin bonding systems, the evolution and working mechanisms of current bonding systems, and studies evaluating different parameters of contemporary bonding agents used in clinical cases.

Keywords

Adhesion, bond strength, dentin bonding agents, restorative materials

References

1. Eligüzeloğlu E. Son dönem geliştirilen adeziv sistemler. Ondokuz Mayıs Üniversitesi Diş Hekimliği Fakültesi Dergisi 2009;10(1):22-29.
2. Arhun N. Adezyon ve adeziv sistemler. Türkiye Klinikleri Diş Hekimliği Dergisi – Restoratif Diş Hekimliği Özel Konuları 2017;3(3):113-127.
3. Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G. Classification review of dental adhesive systems: From the IV generation to the universal type. Ann Stomatol. 2017;8:1-9.
4. Buonocore M. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Dent Res. 1955;34:849-853.
5. Joseph P, Yadav C, Satheesh K, Rahna R. Comparative evaluation of the bonding efficacy of sixth, seventh and eighth generation bonding agents: An in vitro study. Int Res J Pharm. 2013;4(9):143-147.
6. Kugel G, Ferrari M. The science of bonding: From first to sixth generation. J Am Dent Assoc. 2000;131:20-25.
7. Kanca J. A method for bonding to tooth structure using phosphoric acid as a dentin-enamel conditioner. Quintessence Int. 1991;22:285-290.
8. De Munck J, Van Meerbeek B, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. A critical review of the durability of adhesion to tooth tissue: Methods and results. J Dent Res. 2005;84(2):118-132.
9. Pashly EL, Agee K, Pashly DH, Tay F. Effect of one versus two applications of an unfilled, all-in-one adhesive on dentine bonding. J Dent. 2002;30:83-90.
10. Abraham S, Ghonmode WN, Saujanya KP, Jaju N, Tambe VH, Yawalikar PP. Effect of grape seed extracts on bond strength of bleached enamel using fifth and seventh generation bonding agents. J Int Oral Health. 2013;5:101-107.
11. Alex G. Adhesive considerations in the placement of direct composite restorations. Compend Contin Educ Dent. 2008;29(1):20-25.
12. Mozner N, Salz U, Zimmermann J. Chemical aspects of self-etching enamel-dentin adhesives: A systematic review. Dent Mater. 2005;21:895-910.
13. Pashley DH, Tay FR. Aggressiveness of contemporary self-etching adhesives. Part II: Etching effects on unground enamel. Dent Mater. 2001;17(5):430-444.
14. Başaran G, Ozer T, Devecioğlu Kama J. Comparison of a recently developed nanofiller self-etching primer adhesive with other self-etching primers and conventional acid etching. Eur J Orthod. 2009;31(3):271-275.
15. Kasraei SH, Atai M, Khamverdi Z, Khalegh Nejad S. Effect of nanofiller addition to an experimental dentin adhesive on microtensile bond strength to human dentin. J Dent (Tehran). 2009;6(2):91-96.
16. Gordan VV, Vargas MA, Cobb DS, Denehey GE. Evaluation of adhesive systems using acidic primers. Am J Dent. 1997;10:219-223.
17. Oğuzcan MŞ. Comparison of total etch systems and self etch systems. J Agent. 2016;8:16-22.
18. Breschi L, Mazzoni A, Ruggeri A, Cadenaro M, Di Lenarda R, De Stefano D, et al. Dental adhesion review: Aging and stability of the bonded interface. Dent Mater. 2008;24:90-101.
19. Hashimoto M, Tay FR, Svizero NR, Gee AJ, Feilzer AJ, Sano H, et al. The effects of common errors on sealing ability of total-etch adhesives. Dent Mater. 2006;22:560-568.
20. Van Meerbeek B, De Munck J, Mattar D, Van Landuyt K, Lambrechts P. Microtensile bond strengths of an etch-and-rinse and self-etch adhesive to enamel and dentin as a function of surface treatment. Oper Dent. 2003;28(5):647-660.
21. Sundfeld RH, Valentino TA, Alexandre RS, Briso ALF, Sundefeld M. Hybrid layer thickness and resin tag length of a self-etching adhesive bonded to sound dentin. J Dent. 2005;33:675-681.
22. Peumans M, De Munck J, Van Landuyt KL, Poitevin A, Lambrechts P, Van Meerbeek B. Eightyear clinical evaluation of a two-step self-etch adhesive with and without selective enamel etching. Dent Mater. 2010;26:1176-1184.
23. Reis A, Grandi V, Carlotto L, Bortoli G, Patzlaff R, Accorinte MLR, et al. Effect of smear layer thickness and acidity of self-etching solutions on early and long-term bond strength to dentin. J Dent. 2005;33:549-559.
24. Hashimoto M, Ito S, Tay FR, et al. Fluid movement across the resin-dentin interface during and after bonding. J Dent Res. 2004;83:843-848.
25. Giannini M, Makishi P, Ayres AP, Vermelho PM, Fronza BM, Nikaido T, et al. Self-etch adhesive systems: A literature review. Braz Dent J. 2015;26:3- 10.
26. Van Landuyt KL, Snauwaert J, Peumans M, De Munck J, Lambrechts P, Van Meerbeek B. The role of HEMA in one-step self-etch adhesives. Dent Mater. 2008;24:1412-1419.
27. Van Landuyt KL, De Munck J, Mine A, Cardoso MV, Peumans M, Van Meerbeek B. Filler debonding and subhybrid layer failures in self-etch adhesives. J Dent Res. 2010;89(10):1045-1050.
28. Erickson RL, Barkmeier WW, Kimmes NS. Bond strength of self-etch adhesives to pre-etched enamel. Dent Mater. 2009;25:1187-1194.
29. Rotta M, Bresciani P, Moura SK, Grande RH, Hilgert LA, Baratieri LN, et al. Effects of phosphoric acid pretreatment and substitution of bonding resin on bonding effectiveness of self-etching systems to enamel. J Adhes Dent. 2007;9:537-545.
30. Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, et al. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials. 2007;28(26):3757-3775.
31. Cardoso MV, de Almeida Neves A, Mine A, Coutinho E, Van Landuyt K, De Munck J, et al. Current aspects on bonding effectiveness and stability in adhesive dentistry. Aust Dent J. 2011;56(Suppl 1):31-44.
32. Yoshida Y, Yoshihara K, Nagaoka N, Hayakawa S, Torii Y, Ogawa T, et al. Self-assembled nano-layering at the adhesive interface. J Dent Res. 2012;91(4):376-381.
33. Hanabusa M, Mine A, Kuboki T, Momoi Y, Van Ende A, Van Meerbeek B, et al. Bonding effectiveness of a new multi-mode adhesive to enamel and dentin. J Dent. 2012;40(6):475-484.
34. Perdigao J, Sezinando A, Monteiro PC. Laboratory bonding ability of a multi-purpose dentin adhesive. Am J Dent. 2012;25(3):153-158.
35. Sri Ganesh A. Comparative evaluation of shear bond strength between fifth, sixth, seventh, and eighth generation bonding agents: An in vitro study. Indian J Dent Res. 2020;31(5):752-757.
36. Sideridou I, Tserki V, Papanastasiou G. Study of water sorption, solubility, and modulus of elasticity of lightcured dimethacrylate-based dental resins. Biomaterials. 2003;24:655-665.
37. Breschi L, Maravic T, Cunha SR, Comba A, Cadenaro M, Tjäderhane L, et al. Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications. Dent Mater. 2018;34(1):90-101.
38. Tay FR, Gwinnett JA, Wei SH. Micro-morphological spectrum from overdrying to overwetting acidconditioned dentin in water-free acetone-based, singlebottle primer/adhesives. Dent Mater.1996;12(4):236-244.
39. Hardan L, Bourgi R, Kharouf N, Mancino D, Zarow M, Jakubowicz N, et al. Bond strength of universal adhesives to dentin: A systematic review and metaanalysis. Polymers. 2021;13(3):1-35.
40. Akram Z, Daood U, Aati S, Ngo H, Fawzy AS. Formulation of pH-sensitive chlorhexidine-loaded mesoporous silica nanoparticles modified experimental dentin adhesive. Mater Sci Eng C. 2021;122:111894.
41. Akram Z, Aati S, Clode P, Saunders M, Ngo H, Fawzy AS. Formulation of nano-graphene doped with nano silver modified dentin bonding agents with enhanced interfacial stability and antibiofilm properties. Dent Mater. 2022;38(2):347-362.
42. Brkanović S, Sever EK, Vukelja J, Ivica A, Miletić I, Krmek SJ. Comparison of different universal adhesive systems on dentin bond strength. Materials. 2023;16(4):1-15.
43. Taylor MJ, Lynch E. Microleakage. J Dent. 1992;20(1):3-10.
44. Van Meerbeek B, De Munck J, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. Buonocore memorial lecture: Adhesion to enamel and dentin—current status and future challenges. Oper Dent. 2003;28(3):215-235.
45. Fathpour K, Bazazzade A, Mirmohammadi H. A comparative study of cervical composite restorations microleakage using dental universal bonding and twostep self-etch adhesive. J Contemp Dent Pract. 2021;22(9):1035-1040.
46. Akram Z, Daood U, Aati S, Ngo H, Fawzy AS. Formulation of pH-sensitive chlorhexidine-loaded mesoporous silica nanoparticles modified experimental dentin adhesive. Mater Sci Eng C. 2021;122:111894.
47. Sengar EV, Mulay S, Beri L, Gupta A, Almohareb T, Binalrimal S, et al. Comparative evaluation of microleakage of flowable composite resin using etchand-rinse, self-etch adhesive systems, and selfadhesive flowable composite resin in class V cavities: Confocal laser microscopic study. Materials. 2022;15(14):1-13.
48. Singh S, Bhadauria US, Sharma A, Verma Mathur R. Comparative evaluation of microleakage with total-etch, universal (self-etch mode), and nano adhesive systems in class V composite restorations: An in-vitro study. Cureus. 2023;15(10):1-12.
49. da Rocha LS, de Oliveira DF, de Lima CLV, do Nascimento TG, de Freitas JD, de Freitas JMD, et al. Effect of propolis added to single-bottle adhesives on water permeation through the hybrid layer. Eur J Oral Sci. 2024;132(6):1-10.
50. Mohan MC, Geetha P, Soman D, Kunjusankaran RN, Kurup NB, Venugopal K. The effect of salivary contamination on the shear bond strength of seventh- and eighth-generation adhesive systems. Int J Clin Pediatr Dent. 2023;16(Suppl 1):S63-S66.
51. Sugimura R, Tsujimoto A, Hosoya Y, Fischer NG, Barkmeier WW, Takamizawa T, et al. Surface moisture influence on etch-and-rinse universal adhesive bonding. Am J Dent. 2019;32(1):33-38.
52. Jitumori RT, Rodrigues RC, Reis A, Gomes JC, Gomes GM. Effect of dentin moisture on the adhesive properties of luting fiber posts using adhesive strategies. Braz Oral Res. 2023;37:1-11.
53. Dutra-Correa M, Leite AABV, de Cara SPHM, Diniz IMA, Marques MM, Suffredini IB, et al. Antibacterial effects and cytotoxicity of an adhesive containing low concentration of silver nanoparticles. J Dent. 2018;77:66- 71.
54. Yousaf A, Aman N, Manzoor MA, Shah JA, Dilrasheed. Postoperative sensitivity of self-etch versus total-etch adhesive. J Coll Physicians Surg Pak. 2014;24(6):383-386.
55. Koohpeima F, Mokhtari MJ, Khalafi S. The effect of silver nanoparticles on composite shear bond strength to dentin with different adhesion protocols. J Appl Oral Sci. 2017;25(4):367-373.
56. Younus MZ. Comparison between effectiveness of dentine desensitizer and one-bottle self-etch adhesive on dentine hypersensitivity. Technol Health Care. 2021;29(6):1153-1159.
57. Gug HR, Park YH, Park SJ, Jang JY, Lee JH, Lee DS, et al. Novel strategy for dental caries by physiologic dentin regeneration with CPNE7 peptide. Arch Oral Biol. 2022;143:105531.
58. Park EH, Na YK, Gug H, Lee DS, Park JC, Park SH, et al. Development of a new universal adhesive containing CPNE7-derived peptide and its potential role in reducing postoperative sensitivity. Dent Mater J. 2023;42(4):501-508.
59. Alghauli MA, Alqutaibi AY, Wille S, Kern M. Clinical reliability of self-adhesive luting resins compared to other adhesive procedures: A systematic review and meta-analysis. J Dent. 2023;129:104394.

DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER

Year 2025, Volume: 11 Issue: 1, 1 - 10, 27.03.2025

Nezahat Nurefşan Evli , Simin Kocaaydın

https://doi.org/10.21306/dishekimligi.1581695

Abstract

Adezyon, restoratif diş hekimliğinde kritik bir süreç olup, mineralize diş dokuları ile dolgu materyalleri arasında sağlam bir bağlantı oluşturmaktadır. Dentin bonding ajanları ise bu bağlanmayı artıran ince rezin tabakalar olarak tanımlanmaktadır. Klinik uygulamalarda, tedavi süresini azaltmak, uygulama kolaylığı sağlamak ve restorasyon dayanıklılığını artırmak amacıyla farklı jenerasyon bonding ajanları geliştirilmiştir. Bu adeziv sistemler, restoratif tedavilerde daha etkili sonuçlar sağlamakta ve diş dokusunu koruma hedefiyle geliştirilmeye devam etmektedir. Bu derlemede, adezyonun tanımı ve önemi ile dentin bonding sistemlerin tarihçesi, sınıflandırmaları, karşılaştırmaları, güncel bonding sistemlerin gelişimi ve çalışma mekanizmaları ayrıntılı olarak incelenmiştir. Ayrıca klinik vakalarda kullanılan güncel bonding ajanlarının farklı parametrelerle karşılaştırmalarının değerlendirildiği çalışmalara yer verilmiştir.

Keywords

Adezyon, bağlanma dayanıklılığı, dentin bonding ajanları, restoratif materyaller

References

1. Eligüzeloğlu E. Son dönem geliştirilen adeziv sistemler. Ondokuz Mayıs Üniversitesi Diş Hekimliği Fakültesi Dergisi 2009;10(1):22-29.
2. Arhun N. Adezyon ve adeziv sistemler. Türkiye Klinikleri Diş Hekimliği Dergisi – Restoratif Diş Hekimliği Özel Konuları 2017;3(3):113-127.
3. Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G. Classification review of dental adhesive systems: From the IV generation to the universal type. Ann Stomatol. 2017;8:1-9.
4. Buonocore M. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Dent Res. 1955;34:849-853.
5. Joseph P, Yadav C, Satheesh K, Rahna R. Comparative evaluation of the bonding efficacy of sixth, seventh and eighth generation bonding agents: An in vitro study. Int Res J Pharm. 2013;4(9):143-147.
6. Kugel G, Ferrari M. The science of bonding: From first to sixth generation. J Am Dent Assoc. 2000;131:20-25.
7. Kanca J. A method for bonding to tooth structure using phosphoric acid as a dentin-enamel conditioner. Quintessence Int. 1991;22:285-290.
8. De Munck J, Van Meerbeek B, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. A critical review of the durability of adhesion to tooth tissue: Methods and results. J Dent Res. 2005;84(2):118-132.
9. Pashly EL, Agee K, Pashly DH, Tay F. Effect of one versus two applications of an unfilled, all-in-one adhesive on dentine bonding. J Dent. 2002;30:83-90.
10. Abraham S, Ghonmode WN, Saujanya KP, Jaju N, Tambe VH, Yawalikar PP. Effect of grape seed extracts on bond strength of bleached enamel using fifth and seventh generation bonding agents. J Int Oral Health. 2013;5:101-107.
11. Alex G. Adhesive considerations in the placement of direct composite restorations. Compend Contin Educ Dent. 2008;29(1):20-25.
12. Mozner N, Salz U, Zimmermann J. Chemical aspects of self-etching enamel-dentin adhesives: A systematic review. Dent Mater. 2005;21:895-910.
13. Pashley DH, Tay FR. Aggressiveness of contemporary self-etching adhesives. Part II: Etching effects on unground enamel. Dent Mater. 2001;17(5):430-444.
14. Başaran G, Ozer T, Devecioğlu Kama J. Comparison of a recently developed nanofiller self-etching primer adhesive with other self-etching primers and conventional acid etching. Eur J Orthod. 2009;31(3):271-275.
15. Kasraei SH, Atai M, Khamverdi Z, Khalegh Nejad S. Effect of nanofiller addition to an experimental dentin adhesive on microtensile bond strength to human dentin. J Dent (Tehran). 2009;6(2):91-96.
16. Gordan VV, Vargas MA, Cobb DS, Denehey GE. Evaluation of adhesive systems using acidic primers. Am J Dent. 1997;10:219-223.
17. Oğuzcan MŞ. Comparison of total etch systems and self etch systems. J Agent. 2016;8:16-22.
18. Breschi L, Mazzoni A, Ruggeri A, Cadenaro M, Di Lenarda R, De Stefano D, et al. Dental adhesion review: Aging and stability of the bonded interface. Dent Mater. 2008;24:90-101.
19. Hashimoto M, Tay FR, Svizero NR, Gee AJ, Feilzer AJ, Sano H, et al. The effects of common errors on sealing ability of total-etch adhesives. Dent Mater. 2006;22:560-568.
20. Van Meerbeek B, De Munck J, Mattar D, Van Landuyt K, Lambrechts P. Microtensile bond strengths of an etch-and-rinse and self-etch adhesive to enamel and dentin as a function of surface treatment. Oper Dent. 2003;28(5):647-660.
21. Sundfeld RH, Valentino TA, Alexandre RS, Briso ALF, Sundefeld M. Hybrid layer thickness and resin tag length of a self-etching adhesive bonded to sound dentin. J Dent. 2005;33:675-681.
22. Peumans M, De Munck J, Van Landuyt KL, Poitevin A, Lambrechts P, Van Meerbeek B. Eightyear clinical evaluation of a two-step self-etch adhesive with and without selective enamel etching. Dent Mater. 2010;26:1176-1184.
23. Reis A, Grandi V, Carlotto L, Bortoli G, Patzlaff R, Accorinte MLR, et al. Effect of smear layer thickness and acidity of self-etching solutions on early and long-term bond strength to dentin. J Dent. 2005;33:549-559.
24. Hashimoto M, Ito S, Tay FR, et al. Fluid movement across the resin-dentin interface during and after bonding. J Dent Res. 2004;83:843-848.
25. Giannini M, Makishi P, Ayres AP, Vermelho PM, Fronza BM, Nikaido T, et al. Self-etch adhesive systems: A literature review. Braz Dent J. 2015;26:3- 10.
26. Van Landuyt KL, Snauwaert J, Peumans M, De Munck J, Lambrechts P, Van Meerbeek B. The role of HEMA in one-step self-etch adhesives. Dent Mater. 2008;24:1412-1419.
27. Van Landuyt KL, De Munck J, Mine A, Cardoso MV, Peumans M, Van Meerbeek B. Filler debonding and subhybrid layer failures in self-etch adhesives. J Dent Res. 2010;89(10):1045-1050.
28. Erickson RL, Barkmeier WW, Kimmes NS. Bond strength of self-etch adhesives to pre-etched enamel. Dent Mater. 2009;25:1187-1194.
29. Rotta M, Bresciani P, Moura SK, Grande RH, Hilgert LA, Baratieri LN, et al. Effects of phosphoric acid pretreatment and substitution of bonding resin on bonding effectiveness of self-etching systems to enamel. J Adhes Dent. 2007;9:537-545.
30. Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, et al. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials. 2007;28(26):3757-3775.
31. Cardoso MV, de Almeida Neves A, Mine A, Coutinho E, Van Landuyt K, De Munck J, et al. Current aspects on bonding effectiveness and stability in adhesive dentistry. Aust Dent J. 2011;56(Suppl 1):31-44.
32. Yoshida Y, Yoshihara K, Nagaoka N, Hayakawa S, Torii Y, Ogawa T, et al. Self-assembled nano-layering at the adhesive interface. J Dent Res. 2012;91(4):376-381.
33. Hanabusa M, Mine A, Kuboki T, Momoi Y, Van Ende A, Van Meerbeek B, et al. Bonding effectiveness of a new multi-mode adhesive to enamel and dentin. J Dent. 2012;40(6):475-484.
34. Perdigao J, Sezinando A, Monteiro PC. Laboratory bonding ability of a multi-purpose dentin adhesive. Am J Dent. 2012;25(3):153-158.
35. Sri Ganesh A. Comparative evaluation of shear bond strength between fifth, sixth, seventh, and eighth generation bonding agents: An in vitro study. Indian J Dent Res. 2020;31(5):752-757.
36. Sideridou I, Tserki V, Papanastasiou G. Study of water sorption, solubility, and modulus of elasticity of lightcured dimethacrylate-based dental resins. Biomaterials. 2003;24:655-665.
37. Breschi L, Maravic T, Cunha SR, Comba A, Cadenaro M, Tjäderhane L, et al. Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications. Dent Mater. 2018;34(1):90-101.
38. Tay FR, Gwinnett JA, Wei SH. Micro-morphological spectrum from overdrying to overwetting acidconditioned dentin in water-free acetone-based, singlebottle primer/adhesives. Dent Mater.1996;12(4):236-244.
39. Hardan L, Bourgi R, Kharouf N, Mancino D, Zarow M, Jakubowicz N, et al. Bond strength of universal adhesives to dentin: A systematic review and metaanalysis. Polymers. 2021;13(3):1-35.
40. Akram Z, Daood U, Aati S, Ngo H, Fawzy AS. Formulation of pH-sensitive chlorhexidine-loaded mesoporous silica nanoparticles modified experimental dentin adhesive. Mater Sci Eng C. 2021;122:111894.
41. Akram Z, Aati S, Clode P, Saunders M, Ngo H, Fawzy AS. Formulation of nano-graphene doped with nano silver modified dentin bonding agents with enhanced interfacial stability and antibiofilm properties. Dent Mater. 2022;38(2):347-362.
42. Brkanović S, Sever EK, Vukelja J, Ivica A, Miletić I, Krmek SJ. Comparison of different universal adhesive systems on dentin bond strength. Materials. 2023;16(4):1-15.
43. Taylor MJ, Lynch E. Microleakage. J Dent. 1992;20(1):3-10.
44. Van Meerbeek B, De Munck J, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. Buonocore memorial lecture: Adhesion to enamel and dentin—current status and future challenges. Oper Dent. 2003;28(3):215-235.
45. Fathpour K, Bazazzade A, Mirmohammadi H. A comparative study of cervical composite restorations microleakage using dental universal bonding and twostep self-etch adhesive. J Contemp Dent Pract. 2021;22(9):1035-1040.
46. Akram Z, Daood U, Aati S, Ngo H, Fawzy AS. Formulation of pH-sensitive chlorhexidine-loaded mesoporous silica nanoparticles modified experimental dentin adhesive. Mater Sci Eng C. 2021;122:111894.
47. Sengar EV, Mulay S, Beri L, Gupta A, Almohareb T, Binalrimal S, et al. Comparative evaluation of microleakage of flowable composite resin using etchand-rinse, self-etch adhesive systems, and selfadhesive flowable composite resin in class V cavities: Confocal laser microscopic study. Materials. 2022;15(14):1-13.
48. Singh S, Bhadauria US, Sharma A, Verma Mathur R. Comparative evaluation of microleakage with total-etch, universal (self-etch mode), and nano adhesive systems in class V composite restorations: An in-vitro study. Cureus. 2023;15(10):1-12.
49. da Rocha LS, de Oliveira DF, de Lima CLV, do Nascimento TG, de Freitas JD, de Freitas JMD, et al. Effect of propolis added to single-bottle adhesives on water permeation through the hybrid layer. Eur J Oral Sci. 2024;132(6):1-10.
50. Mohan MC, Geetha P, Soman D, Kunjusankaran RN, Kurup NB, Venugopal K. The effect of salivary contamination on the shear bond strength of seventh- and eighth-generation adhesive systems. Int J Clin Pediatr Dent. 2023;16(Suppl 1):S63-S66.
51. Sugimura R, Tsujimoto A, Hosoya Y, Fischer NG, Barkmeier WW, Takamizawa T, et al. Surface moisture influence on etch-and-rinse universal adhesive bonding. Am J Dent. 2019;32(1):33-38.
52. Jitumori RT, Rodrigues RC, Reis A, Gomes JC, Gomes GM. Effect of dentin moisture on the adhesive properties of luting fiber posts using adhesive strategies. Braz Oral Res. 2023;37:1-11.
53. Dutra-Correa M, Leite AABV, de Cara SPHM, Diniz IMA, Marques MM, Suffredini IB, et al. Antibacterial effects and cytotoxicity of an adhesive containing low concentration of silver nanoparticles. J Dent. 2018;77:66- 71.
54. Yousaf A, Aman N, Manzoor MA, Shah JA, Dilrasheed. Postoperative sensitivity of self-etch versus total-etch adhesive. J Coll Physicians Surg Pak. 2014;24(6):383-386.
55. Koohpeima F, Mokhtari MJ, Khalafi S. The effect of silver nanoparticles on composite shear bond strength to dentin with different adhesion protocols. J Appl Oral Sci. 2017;25(4):367-373.
56. Younus MZ. Comparison between effectiveness of dentine desensitizer and one-bottle self-etch adhesive on dentine hypersensitivity. Technol Health Care. 2021;29(6):1153-1159.
57. Gug HR, Park YH, Park SJ, Jang JY, Lee JH, Lee DS, et al. Novel strategy for dental caries by physiologic dentin regeneration with CPNE7 peptide. Arch Oral Biol. 2022;143:105531.
58. Park EH, Na YK, Gug H, Lee DS, Park JC, Park SH, et al. Development of a new universal adhesive containing CPNE7-derived peptide and its potential role in reducing postoperative sensitivity. Dent Mater J. 2023;42(4):501-508.
59. Alghauli MA, Alqutaibi AY, Wille S, Kern M. Clinical reliability of self-adhesive luting resins compared to other adhesive procedures: A systematic review and meta-analysis. J Dent. 2023;129:104394.

There are 59 citations in total.

Details

Primary Language	Turkish
Subjects	Dental Materials and Equipment
Journal Section	Collection
Authors	Nezahat Nurefşan Evli 0009-0004-1260-6162 Simin Kocaaydın 0000-0003-2577-7513
Publication Date	March 27, 2025
Submission Date	November 11, 2024
Acceptance Date	January 13, 2025
Published in Issue	Year 2025 Volume: 11 Issue: 1

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APA	Evli, N. N., & Kocaaydın, S. (2025). DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi), 11(1), 1-10. https://doi.org/10.21306/dishekimligi.1581695
AMA	Evli NN, Kocaaydın S. DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER. J Int Dent Sci. March 2025;11(1):1-10. doi:10.21306/dishekimligi.1581695
Chicago	Evli, Nezahat Nurefşan, and Simin Kocaaydın. “DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 11, no. 1 (March 2025): 1-10. https://doi.org/10.21306/dishekimligi.1581695.
EndNote	Evli NN, Kocaaydın S (March 1, 2025) DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 11 1 1–10.
IEEE	N. N. Evli and S. Kocaaydın, “DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER”, J Int Dent Sci, vol. 11, no. 1, pp. 1–10, 2025, doi: 10.21306/dishekimligi.1581695.
ISNAD	Evli, Nezahat Nurefşan - Kocaaydın, Simin. “DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi) 11/1 (March 2025), 1-10. https://doi.org/10.21306/dishekimligi.1581695.
JAMA	Evli NN, Kocaaydın S. DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER. J Int Dent Sci. 2025;11:1–10.
MLA	Evli, Nezahat Nurefşan and Simin Kocaaydın. “DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER”. Journal of International Dental Sciences (Uluslararası Diş Hekimliği Bilimleri Dergisi), vol. 11, no. 1, 2025, pp. 1-10, doi:10.21306/dishekimligi.1581695.
Vancouver	Evli NN, Kocaaydın S. DENTİN BAĞLAYICI AJANLARDA GÜNCEL GELİŞMELER. J Int Dent Sci. 2025;11(1):1-10.

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The journal receives submissions of research articles, case reports and review-type publications, and these are indexed by international and national indexes.

The International Journal of Dental Sciences has been indexed by Europub, the Asian Science Citation Index, the Asos index, the ACAR index and Google Scholar. In addition, applications were made to TR Index and other indexes.