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FARKLI SPOR DALLARINDA EGZERSİZİN HORMONLAR ÜZERİNDEKİ ETKİSİ

Year 2025, Volume: 3 Issue: 2, 208 - 225, 31.12.2025
https://doi.org/10.71243/dksbd.1823128

Abstract

Bu sistematik derleme ve istatistiksel tahmin çalışması, haftalık düzenli (4 gün ve üzeri) antrenman yapan futbol, atletizm, yüzme, basketbol, halter, futsal ve triatlon branşlarındaki sporcularda ağız sürüntüsü (tükürük) örneklerinden elde edilen hormonal ve immünolojik biyobelirteç düzeylerini sistematik olarak karşılaştırmayı amaçlamıştır. Çalışma, Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) yönergelerine uygun olarak yürütülmüş ve 2016 yılına kadar yayımlanmış orijinal araştırmaların verilerini incelemeye odaklanmıştır. Veri tabanı taraması, Google Scholar, PubMed ve Web of Science Core Collection gibi platformlarda "salivary hormones", "cortisol", "testosterone", "IgA" ve "alpha amylase" gibi anahtar kelimelerin boolean kombinasyonları kullanılarak gerçekleştirilmiştir.
Dahil etme kriterlerini karşılayan 14 çalışma sistematik incelemeye alınmıştır4. İncelenen temel parametreler Kortizol, Testosteron, Sekretuar İmmünoglobulin A (sIgA) ve Alfa-amilaz düzeyleri olmuştur. Verilerin analizi, IBM SPSS Statistics 17.0 kullanılarak, normal dağılımı sağlandığında bağımsız örneklem t-testi ve sağlanmadığında Mann–Whitney U testi ile yapılmıştır. Branşlar arası ilişkiler Pearson korelasyonu (r) ile, etki büyüklükleri ise Cohen’s d ile raporlanmıştır.. Anlamlılık düzeyi p < 0.05 olarak belirlenmiştir.
Bulgular
Analiz sonuçlarına göre, farklı spor branşları arasında hormonal ve sempatik aktivite profillerinde anlamlı farklılıklar saptanmıştır (Tablo 2/3)
Anabolik Baskınlık: Yüzme (T/C oranı Z = +0.49) ve Futsal (T/C oranı Z = +0.60) branşlarında en güçlü anabolik denge gözlemlenirken, Halter sporcularında en yüksek Testosteron düzeyi (180.2 ± 33.5 pg/mL, p = 0.029*) tespit edilmiştir.
Katabolik Stres: Halter (Kortizol Z = +0.55) ve Triatlon (Kortizol Z = +0.33) sporcularında katabolik eğilimin ve akut stresin belirgin olduğu bulunmuştur. Yüzücülerde ise en düşük stres yükü (3.94±1.10 ng/mL, p = 0.048*) belirlenmiştir.
Sempatik Aktivite: Halter (Alfa-amilaz Z= +0.58) ve Futsal (Alfa-amilaz Z = +0.48) branşlarında sempatik aktivite düzeyi yüksek iken, Futbolcular (48.7 ±12.9 U/mL, p = 0.012*) anlamlı sempatik aktivite göstermiştir.
Bağışıklık Yanıtı: Atletizm sIgA Z = -0.36) ve Halter (sIgA Z = -0.41)$ branşlarında sIgA düzeylerinde baskılanma eğilimi mevcuttur. Yüzme (sIgAZ= +0.33) ve Futsal sIgAZ= +0.40) branşlarında ise bağışıklık yanıtı nispeten daha dengeli veya yüksek bulunmuştur.
Bu çalışma, tükürük hormon analizlerinin farklı yüklenme profillerine sahip branşlarda nasıl değiştiğini sistematik biçimde karşılaştıran ilk Türkçe derlemelerden biri olması açısından önem taşımaktadır. Elde edilen bulgular, antrenman yükü planlaması, sportif aşırı yüklenme (overtraining) erken uyarı sistemleri ve bireysel hormon profillerine göre toparlanma optimizasyonu konularında bilimsel katkı sağlamayı hedeflemektedir.

References

  • Adlercreutz H, Hikkinen M, Kuoppasalmi K, N«veri H, Huhtaniemi I, Tikkanen H, Remes K. Dessypris A, Karvonen J. Effects of training on plasma anabolic and catabolic hormones and their response duiing physical exercise. Int J SpOrls Med 1986 ;7:27 -8
  • Ali, N., & Pruessner, J. C. (2012). The salivary alpha amylase over cortisol ratio as a marker to assess dysregulation of the stress systems. Physiology & behavior , 106 (1), 65-72.
  • Behr, MB, Gerraughty, LE, Ondrak, KS, Battaglini, CL, & Hackney, AC (2009). Cortisol responses to supramaximal exercise. Brazilian Journal of Biomotricity , 3 (3), 281 286.
  • Borresen, J., & Lambert, M. I. (2009). The quantification of training load, the training response and the effect on performance. Sports medicine , 39 (9), 779-795.
  • Copeland, J. L., Consitt, L. A., & Tremblay, M. S. (2002). Hormonal responses to endurance and resistance exercise in females aged 19–69 years. The Journals of Gerontology: Series A , 57 (4), B158-B165.
  • Corbett, Lauren, Cameron Muir, Izabella A. Ludwa, Matthew Yao, Brian W. Timmons, Bareket Falk, and Panagiota Klentrou. "The relationship between mucosal immunity and upper respiratory tract infections in girls." (2010): 579–587.
  • Ginsburg, G.S., O'Toole, M., Rimm, E., Douglas, P.S., & Rifai, N. (2001). Gender differences in exercise-induced changes in sex hormone levels and lipid peroxidation in athletes party cipating in the Hawaii Ironman triathlon: Ginsburg-gender and exercise-induced lipid peroxidation. Clinica Chimica Acta, 305(1-2), (00)00427-7 131–139.
  • Grisdale, B. S. (1986). The effects of catecholamines on protein metabolism in pigs and sheep . Iowa State University.
  • Gleeson, M., McDonald, W.A., Pyne, D.B., Clancy, R.L., Cripps, AW, Francis, J.L., & Fricker, P.A. (2000). Immune status and respiratory illness for elite swimmers during a 12-week training cycle. International journal of sports medicine , 21 (04), 302-307.
  • Henry, J. P. (1980). Present concept of stress theory. Catecholamines and stress: Recent advances , 557-571. Israel, S. (1976). Zur Problematic des Ubertrainings aus internistischer und leistungsphysiologischer Sicht. Medizin und Sport , 16 , 1-12.
  • Kindermann, W. (1986). Overtraining: expression of a disturbed autonomic regulation. Dtsch Z Sportmed , 37 , 238-245.
  • Kraemer, W. J. (1987). Endocrine responses to resistance exercise .
  • Kraemer, W. J., Ratamess, N. A., & French, D. N. (2002). Resistance training for health and performance. Current sports medicine reports , 1 (3), 165-171.
  • Kraemer, W. J., & Ratamess, N. A. (2005). Hormonal responses and adaptations to resistance exercise and training. Sports medicine , 35 (4), 339-361.
  • Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: a practical guide. Sports Health, 4(2), 128-138
  • Laurent, H.K., Stroud, L.R., Brush, B., D'Angelo, C., & Granger, D.A. (2015). Secretory IgA reactivity to social threat in youth: Relations with HPA, ANS, and behavior. Psychoneuroendocrinology , 59 , 81–90.
  • Lehmann M, Foster C, Dickhuth HH, Gastmann U (1998) Autonomic imbalance imbalance and overtraining syndrome. Med Sci Sports Exerc 30:1140–1145
  • Li, C.Y., Hsu, G.S., Suzuki, K., Ko , M.H., & Fang, S.H. (2015). Salivary immune factors, cortisol and testosterone responses in athletes of a competitive 5,000 m race. Chin J Physiol , 58 (4), 263 -9.
  • Moreira, A., Arsati, F., de Oliveira Lima Arsati, YB, Da Silva, DA, & de Araújo, V.C. (2009). Salivary cortisol in top-level professional soccer players. European journal of applied physiology , 106 (1), 25-30.
  • Nieman, D. C. (2000). Exercise effects on systemic immunity. Immunology and cell biology , 78 (5), 496-501. Opstad K. Circadian rhythm of honnones is extinguished during prolonged physical stress, sleep and energy deficiency in young men. Eur J EndocrinoI1994 ;131:56 -66.
  • Papadopoulos, E., Muir, C., Russell, C., Timmons, B. W., Falk, B., & Klentrou, P. (2014). Markers of biological stress and mucosal immunity during a week leading to competition in adolescent swimmers. Journal of immunology research , 2014 (1), 234565.
  • Roberts AC, McClure RD, Weiner RI, Brooks GA. Overtraining Affects male reproductive status. Ferril SteriI (1993 ) ; 60:686-92..
  • Rusko, H. K. (1998). Hormonal responses to endurance training and overtraining in female athletes. Clin J Sport Med , 8 (3), 178-186.
  • Saino, N., Møller, A. P., & Bolzerna, A. M. (1995). Testosterone effects on the immune system and parasite infestations in the barn swallow (Hirundo rustica): an experimental test of the immunocompetence hypothesis. Behavioral Ecology , 6 (4), 397-404 .
  • Snyder, A.C., & Hackney, A.C. (2013). The endocrine system in overtraining. In Endocrinology of Physical Activity and Sport: Second Edition (pp. 523-534). Totowa, NJ: Humana Press.
  • Starzak, DE, Konkol, K.F., & McKune, A.J. (2016). Effects of cardiorespiratory fitness and obesity on salivary secretory IgA and alpha-amylase in South African children. Children , 3 (3), 12.
  • Tremblay, MS, & Chu, SY (2000 ) Hormonal Response to Exercise. Michelle P. Warren, MD Naama W. Constantini, MD , Sports endocrinology (Vol. 23). Totowa, NJ, USA :: Humana Press 1-24. ).
  • Van Anders, S. M. (2010). Gonadal steroids and salivary IgA in healthy young women and men. American Journal of Human Biology, 22 (3), 348–352.
  • Van Den Bos, R., Taris, R., Scheppink, B., de Haan, L., & Verster, J. C. (2014). Salivary cortisol and alpha-amylase levels during an assessment procedure correlate differently with risk-taking measures in male and female police recruits. Frontiers in behavioral neuroscience , 7 , 219.
  • Whitehead R, Wilson Butz J, Kozar B, Vaughn RE (1996) Stress and performance: an application of Gray's three-factor arousal theory to basketball free-throw shooting. J Sports Sci 14:393–401.
  • Wilcox, R.R., Granger, D.A., Szanton, S., & Clark, F. (2014). Diurnal patterns and associations among salivary cortisol, DHEA and alpha-amylase in older adults. Physiology & behavior , 129 , 11-16.

EFFECT OF TAKING EXERCISE ON HORMONES IN DIFFERENT BRANCHES OF SPORTS

Year 2025, Volume: 3 Issue: 2, 208 - 225, 31.12.2025
https://doi.org/10.71243/dksbd.1823128

Abstract

This systematic review and statistical estimation study aimed to systematically compare the levels of hormonal and immunological biomarkers obtained from mouth swab (saliva) samples in athletes in football, track and field, swimming, basketball, weightlifting, futsal, and triathlon who train regularly (4 days or more) per week. The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and focused on examining data from original studies published up to 2016. Database searches were conducted using Boolean combinations of keywords such as "salivary hormones," "cortisol," "testosterone," "IgA," and "alpha amylase" on platforms such as Google Scholar, PubMed, and the Web of Science Core Collection.
Fourteen studies that met the inclusion criteria were included in the systematic review. The main parameters examined were cortisol, testosterone, secretory immunoglobulin A(sIgA), and alpha-amylase levels. Data were analyzed using IBM SPSS Statistics 17.0, using the independent samples t-test when normally distributed and the Mann–Whitney U test when not normally distributed.. Relationships between sport branches were reported with Pearson correlation (r), and effect sizes were reported with Cohen's d. The significance level was determined as p< 0.05.
Findings
According to the analysis results, significant differences were found in hormonal and sympathetic activity profiles among different sports branches (Table 2/3).
Anabolic Dominance: While the strongest anabolic balance was observed in Swimming (T/C ratio Z = +0.49) and Futsal (T/C ratio Z = +0.60) branches, the highest Testosterone level (180.2 ± 33.5 pg/mL, p = 0.029*) was detected in Weightlifting athletes.
Catabolic Stress: Catabolic tendency and acute stress were found to be significant in weightlifting (Cortisol Z = +0.55) and triathlon (Cortisol Z = +0.33) athletes. The lowest stress load was found in swimmers (3.94±1.10 ng/mL, p = 0.048*).
Sympathetic Activity: While sympathetic activity levels were high in Weightlifting (Alpha-amylase Z= +0.58) and Futsal (Alpha-amylase Z = +0.48), Footballers (48.7 ±12.9 U/mL, p = 0.012*) showed significant sympathetic activity.
Immune Response: There was a tendency for suppression in sIgA levels in athletics (sIgA Z = -0.36) and weightlifting (sIgA Z = -0.41 ) . In swimming (sIgA Z = +0.33) and futsal (sIgA Z = +0.40), the immune response was found to be relatively more balanced or higher.
This study is important as it is one of the first Turkish reviews to systematically compare how salivary hormone analyses vary in sport branches/ disciplines with different loading profiles. The findings aim to provide scientific contributions to training load planning , athletic overtraining early warning systems , and recovery optimization based on individual hormone profiles.

References

  • Adlercreutz H, Hikkinen M, Kuoppasalmi K, N«veri H, Huhtaniemi I, Tikkanen H, Remes K. Dessypris A, Karvonen J. Effects of training on plasma anabolic and catabolic hormones and their response duiing physical exercise. Int J SpOrls Med 1986 ;7:27 -8
  • Ali, N., & Pruessner, J. C. (2012). The salivary alpha amylase over cortisol ratio as a marker to assess dysregulation of the stress systems. Physiology & behavior , 106 (1), 65-72.
  • Behr, MB, Gerraughty, LE, Ondrak, KS, Battaglini, CL, & Hackney, AC (2009). Cortisol responses to supramaximal exercise. Brazilian Journal of Biomotricity , 3 (3), 281 286.
  • Borresen, J., & Lambert, M. I. (2009). The quantification of training load, the training response and the effect on performance. Sports medicine , 39 (9), 779-795.
  • Copeland, J. L., Consitt, L. A., & Tremblay, M. S. (2002). Hormonal responses to endurance and resistance exercise in females aged 19–69 years. The Journals of Gerontology: Series A , 57 (4), B158-B165.
  • Corbett, Lauren, Cameron Muir, Izabella A. Ludwa, Matthew Yao, Brian W. Timmons, Bareket Falk, and Panagiota Klentrou. "The relationship between mucosal immunity and upper respiratory tract infections in girls." (2010): 579–587.
  • Ginsburg, G.S., O'Toole, M., Rimm, E., Douglas, P.S., & Rifai, N. (2001). Gender differences in exercise-induced changes in sex hormone levels and lipid peroxidation in athletes party cipating in the Hawaii Ironman triathlon: Ginsburg-gender and exercise-induced lipid peroxidation. Clinica Chimica Acta, 305(1-2), (00)00427-7 131–139.
  • Grisdale, B. S. (1986). The effects of catecholamines on protein metabolism in pigs and sheep . Iowa State University.
  • Gleeson, M., McDonald, W.A., Pyne, D.B., Clancy, R.L., Cripps, AW, Francis, J.L., & Fricker, P.A. (2000). Immune status and respiratory illness for elite swimmers during a 12-week training cycle. International journal of sports medicine , 21 (04), 302-307.
  • Henry, J. P. (1980). Present concept of stress theory. Catecholamines and stress: Recent advances , 557-571. Israel, S. (1976). Zur Problematic des Ubertrainings aus internistischer und leistungsphysiologischer Sicht. Medizin und Sport , 16 , 1-12.
  • Kindermann, W. (1986). Overtraining: expression of a disturbed autonomic regulation. Dtsch Z Sportmed , 37 , 238-245.
  • Kraemer, W. J. (1987). Endocrine responses to resistance exercise .
  • Kraemer, W. J., Ratamess, N. A., & French, D. N. (2002). Resistance training for health and performance. Current sports medicine reports , 1 (3), 165-171.
  • Kraemer, W. J., & Ratamess, N. A. (2005). Hormonal responses and adaptations to resistance exercise and training. Sports medicine , 35 (4), 339-361.
  • Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: a practical guide. Sports Health, 4(2), 128-138
  • Laurent, H.K., Stroud, L.R., Brush, B., D'Angelo, C., & Granger, D.A. (2015). Secretory IgA reactivity to social threat in youth: Relations with HPA, ANS, and behavior. Psychoneuroendocrinology , 59 , 81–90.
  • Lehmann M, Foster C, Dickhuth HH, Gastmann U (1998) Autonomic imbalance imbalance and overtraining syndrome. Med Sci Sports Exerc 30:1140–1145
  • Li, C.Y., Hsu, G.S., Suzuki, K., Ko , M.H., & Fang, S.H. (2015). Salivary immune factors, cortisol and testosterone responses in athletes of a competitive 5,000 m race. Chin J Physiol , 58 (4), 263 -9.
  • Moreira, A., Arsati, F., de Oliveira Lima Arsati, YB, Da Silva, DA, & de Araújo, V.C. (2009). Salivary cortisol in top-level professional soccer players. European journal of applied physiology , 106 (1), 25-30.
  • Nieman, D. C. (2000). Exercise effects on systemic immunity. Immunology and cell biology , 78 (5), 496-501. Opstad K. Circadian rhythm of honnones is extinguished during prolonged physical stress, sleep and energy deficiency in young men. Eur J EndocrinoI1994 ;131:56 -66.
  • Papadopoulos, E., Muir, C., Russell, C., Timmons, B. W., Falk, B., & Klentrou, P. (2014). Markers of biological stress and mucosal immunity during a week leading to competition in adolescent swimmers. Journal of immunology research , 2014 (1), 234565.
  • Roberts AC, McClure RD, Weiner RI, Brooks GA. Overtraining Affects male reproductive status. Ferril SteriI (1993 ) ; 60:686-92..
  • Rusko, H. K. (1998). Hormonal responses to endurance training and overtraining in female athletes. Clin J Sport Med , 8 (3), 178-186.
  • Saino, N., Møller, A. P., & Bolzerna, A. M. (1995). Testosterone effects on the immune system and parasite infestations in the barn swallow (Hirundo rustica): an experimental test of the immunocompetence hypothesis. Behavioral Ecology , 6 (4), 397-404 .
  • Snyder, A.C., & Hackney, A.C. (2013). The endocrine system in overtraining. In Endocrinology of Physical Activity and Sport: Second Edition (pp. 523-534). Totowa, NJ: Humana Press.
  • Starzak, DE, Konkol, K.F., & McKune, A.J. (2016). Effects of cardiorespiratory fitness and obesity on salivary secretory IgA and alpha-amylase in South African children. Children , 3 (3), 12.
  • Tremblay, MS, & Chu, SY (2000 ) Hormonal Response to Exercise. Michelle P. Warren, MD Naama W. Constantini, MD , Sports endocrinology (Vol. 23). Totowa, NJ, USA :: Humana Press 1-24. ).
  • Van Anders, S. M. (2010). Gonadal steroids and salivary IgA in healthy young women and men. American Journal of Human Biology, 22 (3), 348–352.
  • Van Den Bos, R., Taris, R., Scheppink, B., de Haan, L., & Verster, J. C. (2014). Salivary cortisol and alpha-amylase levels during an assessment procedure correlate differently with risk-taking measures in male and female police recruits. Frontiers in behavioral neuroscience , 7 , 219.
  • Whitehead R, Wilson Butz J, Kozar B, Vaughn RE (1996) Stress and performance: an application of Gray's three-factor arousal theory to basketball free-throw shooting. J Sports Sci 14:393–401.
  • Wilcox, R.R., Granger, D.A., Szanton, S., & Clark, F. (2014). Diurnal patterns and associations among salivary cortisol, DHEA and alpha-amylase in older adults. Physiology & behavior , 129 , 11-16.
There are 31 citations in total.

Details

Primary Language Turkish
Subjects Sports Training, Physical Training, Sports and Physical Activity For Disabled, Sports Science and Exercise (Other)
Journal Section Research Article
Authors

Ömer Zambak 0000-0001-7301-3935

Mustafa Koç 0000-0002-3863-8021

Submission Date November 13, 2025
Acceptance Date December 21, 2025
Publication Date December 31, 2025
Published in Issue Year 2025 Volume: 3 Issue: 2

Cite

APA Zambak, Ö., & Koç, M. (2025). FARKLI SPOR DALLARINDA EGZERSİZİN HORMONLAR ÜZERİNDEKİ ETKİSİ. Dede Korkut Spor Bilimleri Dergisi, 3(2), 208-225. https://doi.org/10.71243/dksbd.1823128