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DENTAL BOTOKS UYGULAMALARI

Year 2019, Volume 1, Issue 3, 89 - 102, 31.10.2019

Deniz ERDİL Hamed FARSİANİ Nilsun BAĞIŞ

Abstract

    Botulinum toksini (BT) Clostridium Botulinum tarafından anaerobik koşullar altında üretilen en ölümcül toksinlerden biridir. BT, kolinerjik nöron sinapslarında asetilkolin salınımını bloke ettiği nöromüsküler kavşak (NMJ) üzerindeki etkisiyle kas felcine neden olduğunun öğrenilmesinden itibaren tıpta ve kozmetik alanda kullanılmaya başlanmıştır. Dünyada en yaygın olarak kullanılan BTA Botox®faciodental estetik ve terapötik amaçlara yönelik olarak diş hekimliğinde de kendine yer bulmuştur.  BT’nın terapötik ve dentofasiyal estetik kullanımda etkili ve güvenli sonuçlar elde edilmiştir. Özellikle temporo mandibuler bozukluklar, bruksizm, gummy smile gibi vakalarda radikal cerrahiye göre çok daha az invaziv olması ve yardımcı tedavi olarak fayda sağlaması nedeniyle kendine yer edinmiştir. BT'nın terapötik etkisi geçici ve nispeten güvenli olmasına rağmen, ilgili anatomi ve yüze uygulanan ilaçların sistemik ve lokal yan etkileri hakkında bilgi sahibi olmak esastır.

Keywords

Botulinum toksin A, bruksizm, diş hekimliği

References

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APPLICATION OF DENTAL BOTOX

Year 2019, Volume 1, Issue 3, 89 - 102, 31.10.2019

Deniz ERDİL Hamed FARSİANİ Nilsun BAĞIŞ

Abstract

    Botulinum is one of the most lethal toxins known and botulinum neurotoxin produced under anaerobic conditions by Clostridium Botulinum. BT has been used in medicine and cosmetics since it has been learned that it causes muscle paralysis due to its effect on the neuromuscular junction (NMJ) where it blocks acetylcholine release in cholinergic neuron synapses. The most widely used BTA Botox® in the world has found its place in dentistry for aesthetic and therapeutic purposes such as temporomandibular disorders, bruxism, trigeminal neuralgia, oromandibular spasm, gummy smile, masseterhipertrofisi, sialorrhea. BTA injections are a much more minimally invasive method than radical surgical procedures and can be used as an adjunctive treatment. Although the therapeutic effect of CT is transient and relatively reliable, it is essential to have knowledge of the relevant anatomy and systemic and local side effects of the drugs administered to the face.

Keywords

Botulinum toxin A, bruxism, dentistry

References

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  • 2.Arnon SS, Schechter R, Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, et al. Botulinum toxin as a biological weapon: Medical and public health management. JAMA 2001;285:1059-70.
  • 3.Park KS, Lee CH, Lee JW. JDentAnesthPainMed. 2016 Sep;16(3):151-157.
  • 4. Burgen AS, Dickens F, Zatman LJ. The action of botulinum toxin on the neuro-muscular junction. J Physiol 1949; 109: 10-24.
  • 5. Erbguth FJ. From poison tor emedy: The chequered history of botulinum toxin. J NeuralTransm (Vienna). 2008; 115: 559-65.
  • 6. Scott A. Botulinum toxin injection to correct strabism. Trans Am Ophthalmol Soc. 1979; 79: 924-7.
  • 7. Scott AB. Botulinum toxin injection of eye muscles to correct strabismus. Trans Am Ophthalmol Soc.1981; 79: 734-70.
  • 8. Dastoor SF, Misch CE, Wang HL. Botulinum toxin (Botox) to enhance facial macroesthetics: A literatür ereview. J Oral Implantol. 2007;33(3):164-71.
  • 9. Nayyar P., Kumar P., Nayyar PV. Botox: Broadening theHorizon of Dentistry.J ClinDiagnRes. 2014 Dec;8(12):ZE25-9.
  • 10. Srivastava S, Kharbanda S, Pal US, Shah V. Applications of botulinum toxin in dentistry: A comprehensive review.Natl J MaxillofacSurg. 2015 Jul-Dec;6(2):152-9.
  • 11. Kao I, Drachman DB, Price DL. Botulinum toxin: Mechanism of presynapticblockade. Science. 1976; 193: 1256-8.
  • 12. Simpson LL. The origin, structure, and pharmacological activity of botulinum toxin. PharmacolRev. 1981; 33: 155-88.
  • 13. Jaspers GW, Pijpe J, Jansma J. The use of botulinum toxin type a in cosmetic facial procedures. Int J Oral MaxillofacSurg. 2011; 40: 127-33.
  • 14. de Maio M. Therapeutic uses of botulinum toxin: From facial palsy to autonomic disorders. Expert OpinBiolTher 2008; 8: 791-8.
  • 15. Lora VR, CanalesGde L, Goncalves LM, Meloto CB, Barbosa CM. Prevalence of temporomandibular disorders in post menopausal women and relationship with pain and HRT. Braz Oral Res. 2016.30(1): e100.
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  • 20.Lee KM, Chow J, Hui E, Li W. Botulinum toxin type A injection for the management of myofascial temporomandibular pain disorder. Asian J Oral MaxillofacSurg. 2005;17:100-3
  • 21.Moore AP, Wood GD. Medical treatment of recurrent temporomandibular joint dislocation using botulinum toxin A. BrDent J. 1997; 183:415-7.
  • 22. Daelen B, Thorwirth V, Koch A. Treatment of recurrent dislocation of the temporomandibular joint with type A botulinum toxin. Int J Oral MaxillofacSurg. 1997; 26:458-60.
  • 23.Fu KY, Chen HM, Sun ZP, Zhang ZK, Ma XC. Long-term efficacy of botulinum toxin type A for the treatment of habitual dislocation of the temporomandibular joint. Br J Oral MaxillofacSurg. 2010; 48:281-4.
  • 24.Freund B, Schwartz M, Symington JM. The use of botulinum toxin for the treatment of temporomandibular disorders: Preliminary findings. J Oral MaxillofacSurg. 1999; 57: 916-20.
  • 25.Bakke M, Moller E, Werdelin LM, Dalager T, Kitai N, Kreiborg S. Treatment of severe temporomandibular joint clicking with botulinum toxin in the lateral pterygoid muscle in two cases of anterior disc displacement. Oral Surg Oral Med Oral Pathol Oral RadiolEndod. 2005; 100: 693-700.
  • 26. Daelen B, Thorwirth V, Koch A. Treatment of recurrent dislocation of the temporomandibular joint with type a botulinum toxin. Int J Oral MaxillofacSurg. 1997; 26: 458-60.
  • 27. Blitzer A, Brin MF, Greene PE, et al. Botulinum toxin injection for the treatment of oromandibulardystonia. AnnOtolRhinolLaryngol. 1989;98(2):93-97.
  • 28.Brin MF, Fahn S, Moskowitz C, et al. Localized injections of botulinum toxin for the treatment of focal dystonia and hemi facial spasm. MovDisord. 1987;2(4): 237-54. 29.Hermanowicz N, Truong DD. Treatment of oromandibular dystonia with botulinum toxin. Laryngoscope. 1991;101(11):1216-18.
  • 30.Jankovic J, Orman J. Botulinum toxin for cranial-cervicaldystonia: a double-blind, placebo-controlledstudy. Neurology. 1987; 27:616-23.
  • 31.Laskawi R, Rohrbach S. Oromandibulardystonia. Clinicalforms, diagnosis and examples of therapy with botulinum toxin. Laryngorhinootologie. 2001;80(12):708-13.
  • 32.Tan EK, Jankovic J. Botulinum toxin A in patients with oromandibular dystonia: Long-termfollow-up. Neurology. 1999;53(9):2102-07.
  • 33.Sinha A, Hurakadli M, Yadav P. Botox and dermafillers: The twinface of cosmetic dentistry. Int J ContempDentMedRev. 2015;2015.
  • 34.Elcio JP. BOTOX injections relieve severe facial pain. Available from: http://www. news-medical.net/news/2005/10/25/14010.aspx. [lastcitedon 2009].
  • 35.Bohluli B, Motamedi MH, Bagheri SC, Bayat M, Lassemi E, Navi F, et al. Use of botulinum toxin A for drug-refractory trigeminal neuralgia: Preliminary report. Oral Surg Oral Med Oral Pathol Oral RadiolEndod.2011;111:47-50
  • 36.Benoliel R, Kahn J, Eliav E. 2012. Peripheral painful traumatic trigeminal neuropathies. Oral Dis. 18(4):317–332.
  • 37. Rafael B, Sorin T, Eli E. 2016. Painful traumatic trigeminal neuropathy. Oral MaxillofacSurgClin North Am. 28(3):371–380.
  • 38. Lobbezoo F, Ahlberg J, Raphael KG, Wetselaar P, Glaros AG, Kato T, Santiago V, Winocur E, De Laat A, De Leeuw R, et al. 2018. International consensus on the assessment of bruxism: report of a work in progress. J Oral Rehabil. 45(11):837–844.
  • 39. Manfredini D, Ahlberg J, Winocur E, Lobbezoo F. 2015. Management of sleep bruxism in adults: a qualitative systematic literature review. J Oral Rehabil. 42(11):862–874.
  • 40. Jokubauskas L, Baltrušaitytė A, Pileičikienė G. 2017. Oral appliances for managing sleep bruxism in adults: a systematic review from 2007 to 2017. J Oral Rehabil. 45(1):81–95.
  • 41. Guarda-Nardini L, Manfredini D, Salmaso S, Salmaso L, Tonello S, Ferronato G. 2008. Efficacy of botulinum toxin in treating myofascial pain in bruxers: a controlled placebo pilot study. Cranio. 26(2):126–135.
  • 42. Lee SJ, McCall WD, Kim YK, Chung SC, Chung JW. 2010. Effect of botulinum toxin injection on nocturnal bruxism: a randomized controlled trial. Am J PhysMedRehabil. 89(1):16–23.
  • 43. Redaelli A. 2011. Botulinum toxin A in bruxers: one year experience. SaudiMed J. 32(2):156–158.
  • 44. Shim Y, Lee M, Kato T, Park H, Heo K, Kim S. 2014. Effects of botulinum toxin on jaw motor events during sleep in sleep bruxism patients: a polysomnographic evaluation. J ClinSleepMed. 10(3):291–298.
  • 45. Ondo WG, Simmons JH, Shahid MH, Hashem V, Hunter C, Jankovic J. 2018. On a botulinumtoxin-A injections for sleep bruxism. Neurology. 90(7):e559–e564.46.Muñoz Lora VRM, Del Bel Cury AA, Jabbari B, Lacković Z. J DentRes. 2019 Sep 18:22034519875053.
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  • 48. Tan EK, Jankovic J. Treating severe bruxism with botulinum toxin. J AmDentAssoc. 2000;131(2):211-6.
  • 49.Long H, Liao Z, Wang Y, Liao L, Lai W. Efficacy of botulinum toxins on bruxism: An evidence-based review. IntDent J. 2012; 62:1-5
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Details

Primary Language Turkish
Subjects Dental
Journal Section Periodontology
Authors

Deniz ERDİL This is me
ANKARA ÜNİVERSİTESİ DİŞ HEKİMLİĞİ FAKÜLTESİ
0000-0001-8460-7587
Türkiye

Hamed FARSİANİ This is me
ANKARA ÜNİVERSİTESİ DİŞ HEKİMLİĞİ FAKÜLTESİ
0000-0002-6998-068X
Türkiye

Nilsun BAĞIŞ> (Primary Author)
ANKARA ÜNİVERSİTESİ DİŞ HEKİMLİĞİ FAKÜLTESİ
0000-0003-4301-8502
Türkiye

Publication Date October 31, 2019
Submission Date October 17, 2019
Acceptance Date October 29, 2019
Published in Issue Year 2019, Volume 1, Issue 3

Cite

Bibtex @review { dmj634330, journal = {Dental and Medical Journal - Review}, issn = {2667-7288}, eissn = {2667-7288}, address = {}, publisher = {Mesut TUZLALI}, year = {2019}, volume = {1}, number = {3}, pages = {89 - 102}, title = {DENTAL BOTOKS UYGULAMALARI}, key = {cite}, author = {Erdil, Deniz and Farsiani, Hamed and Bağış, Nilsun} }
APA Erdil, D. , Farsiani, H. & Bağış, N. (2019). DENTAL BOTOKS UYGULAMALARI . Dental and Medical Journal - Review , 1 (3) , 89-102 . Retrieved from https://dergipark.org.tr/en/pub/dmj/issue/50019/634330
MLA Erdil, D. , Farsiani, H. , Bağış, N. "DENTAL BOTOKS UYGULAMALARI" . Dental and Medical Journal - Review 1 (2019 ): 89-102 <https://dergipark.org.tr/en/pub/dmj/issue/50019/634330>
Chicago Erdil, D. , Farsiani, H. , Bağış, N. "DENTAL BOTOKS UYGULAMALARI". Dental and Medical Journal - Review 1 (2019 ): 89-102
RIS TY - JOUR T1 - APPLICATION OF DENTAL BOTOX AU - DenizErdil, HamedFarsiani, NilsunBağış Y1 - 2019 PY - 2019 N1 - DO - T2 - Dental and Medical Journal - Review JF - Journal JO - JOR SP - 89 EP - 102 VL - 1 IS - 3 SN - 2667-7288-2667-7288 M3 - UR - Y2 - 2019 ER -
EndNote %0 Dental and Medical Journal - Review DENTAL BOTOKS UYGULAMALARI %A Deniz Erdil , Hamed Farsiani , Nilsun Bağış %T DENTAL BOTOKS UYGULAMALARI %D 2019 %J Dental and Medical Journal - Review %P 2667-7288-2667-7288 %V 1 %N 3 %R %U
ISNAD Erdil, Deniz , Farsiani, Hamed , Bağış, Nilsun . "DENTAL BOTOKS UYGULAMALARI". Dental and Medical Journal - Review 1 / 3 (October 2019): 89-102 .
AMA Erdil D. , Farsiani H. , Bağış N. DENTAL BOTOKS UYGULAMALARI. Dent & Med J - R. 2019; 1(3): 89-102.
Vancouver Erdil D. , Farsiani H. , Bağış N. DENTAL BOTOKS UYGULAMALARI. Dental and Medical Journal - Review. 2019; 1(3): 89-102.
IEEE D. Erdil , H. Farsiani and N. Bağış , "DENTAL BOTOKS UYGULAMALARI", Dental and Medical Journal - Review, vol. 1, no. 3, pp. 89-102, Oct. 2019
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