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CANDIDA AURIS ENFEKSİYONLARI

Year 2022, Volume: 4 Issue: 2, 124 - 131, 30.06.2022

Abstract

Candida auris yeni ortaya çıkan ancak salgınlar yapabilmesi ve antifungal direnci nedeniyle önemli bir patojendir. İlk 2009 yılında saptanan bu etken, hızlıca global olarak görülmeye başlamış, son yıllarda ülkemizden de tespit edilen olgular olmuştur. Ancak bu güncel küresel halk sağlığı patojeni konsunda bilinmezler çoktur. Biz de bu derleme çalışmasında, C. auris konulu literatürü gözden geçirmeyi amaçladık.

Supporting Institution

yok

Project Number

yok

References

  • 1. Centers for Disease Control and Prevention. Fungal Diseases. Candida auris. Tracking Candida auris. Erişim tarihi: 20 Ocak 2021. https://www.cdc.gov/fungal/candida- auris/tracking-c-auris.html.
  • 2. Moreno MV, Simian ME, Villarroel J, Fuenzalida LM, Yarad MF, Soto A, et al. Primer aislamiento de Candida auris en Chile [First isolation de Candida auris in Chile]. Rev Chilena Infectol. 2019;36(6):767-73.
  • 3. Jeffery-Smith A, Taori S K, Schelenz S, Jeffery K, Johnson E M, Borman A, et al. Candida auris: a review of the literature. Clin Microbiol Rev. 2017; 31 (1). pii:e00029-17.
  • 4. Araúz A B, Cáceres D H, Santiago E, Armstrong P, Arosamena S, Ramos C, et al. Isolation of Candida auris from 9 patients in Central America: Importance of accurate diagnosis and susceptibility testing. Mycoses. 2018; 61: 44-7. doi:10.1111/myc.12709.
  • 5. Lockhart S R, Etienne K A, Vallabhaneni S, Farooqi J, Chowdhary A, Govender N P, et al. Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses. Clin Infect Dis. 2017; 64: 134-40. doi: 10.1093/cid/ciw691.
  • 6. Public Health England (PHE): Guidance for the laboratory investigation, management and infection prevention and control for cases of Candida auris (2016, updated 2017). Erişim tarihi: 20 Ocak 2021. https://www.uptodate.com/contents/society-guideline-links-candidiasis.
  • 7. Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H . Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol.2009; 53:41–4. 8. Dimitrios P Kontoyiannis. Worldwide epidemiology and the burden of Candida auris. 13 April 2019. ECCMID 2019 Amsterdam.
  • 9. Chakrabarti A, Sood P, Rudramurthy SM, Chen S, Kaur H, Capoor M, et al. Incidence, characteristics and outcome of ICU-acquired candidemia in India. Intensive Care Med. 2015;41(2):285-95.
  • 10. Alkan Çeviker S, Günal Ö, Kılıç SS, Köksal E, Tahmaz A. Üçüncü Basamak Hastanede Sağlık Hizmeti ile İlişkili Kandidemilerin Epidemiyolojisi ve Mikrobiyolojik Özellikleri: Tek Merkez Deneyimi. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi. 2020; 7(1): 12-7.
  • 11. Cortegiani A, Misseri G, Fasciana T, Giammanco A, Giarratano A, Chowdhary A. Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris. J Intensive Care. 2018;6:69.
  • 12. de Cássia Orlandi Sardi J, Silva DR, Soares Mendes-Giannini MJ, Rosalen PL. Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options. Microb Pathog. 2018;125:116-121. doi: 10.1016/j.micpath.2018.09.014.
  • 13. Garcia-Jeldes HF, Mitchell R, McGeer A, Rudnick W, Amaratunga K, Vallabhaneni S, et al; CNISP C. auris Interest Group, Bharat A. Prevalence of Candida auris in Canadian acute care hospitals among at-risk patients, 2018. Antimicrob Resist Infect Control. 2020;9(1):82.
  • 14. Rudramurthy SM, Chakrabarti A, Paul RA, Sood P, Kaur H, Capoor MR, et al. Candida auris candidaemia in Indian ICUs: analysis of risk factors. J Antimicrob Chemother. 2017; 72:1794-801.
  • 15. Ayhancı T, Altındiş M. Hızla yayılan çoklu ilaca dirençli maya mantarı: Candida auris. Turk Hij Den Biyol Derg. 2020; 77(1): 123-36.
  • 16. Du H, Bing J, Hu T, Ennis CL, Nobile CJ, Huang G. Candida auris: Epidemiology, biology, antifungal resistance, and virulence. PLoS Pathog. 2022;16(10):e1008921. doi: 10.1371/journal.ppat.1008921.
  • 17. Pathirana RU, Friedman J, Norris HL, Salvatori O, McCall AD, Kay J, et al. Fluconazole-resistant Candida auris is susceptible to salivary histatin 5 killing and to intrinsic host defenses. Antimicrob Agents Chemother. 2018;62(2):e01872-17. doi: 10.1128/AAC.01872-17.
  • 18. Chowdhary A, Tarai B, Singh A, Sharma A. Multidrug-Resistant Candida auris Infections in Critically Ill Coronavirus Disease Patients, India, April-July 2020. Emerg Infect Dis. 2020;26(11):2694-6. doi: 10.3201/eid2611.203504.
  • 19. Villanueva-Lozano H, Treviño-Rangel RJ, González GM, Ramírez-Elizondo MT, Lara-Medrano R, Aleman-Bocanegra MC, et al. Outbreak of Candida auris infection in a COVID-19 hospital in Mexico. Clin Microbiol Infect. 2021;27(5):813–6. doi: 10.1016/j.cmi.2020.12.030.
  • 20. Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP, et al. A Candida auris Outbreak and Its Control in an Intensive Care Setting. N Engl J Med. 2018;379(14):1322-31.
  • 21. García CS, Palop NT, Bayona JVM, García MM, Rodríguez DN, Álvarez MB, et al. Candida auris: report of an outbreak. Enferm Infecc Microbiol Clin (Engl Ed). 2020;38 Suppl 1:39-44.
  • 22. Taori SK, Khonyongwa K, Hayden I, Athukorala GDA, Letters A, Fife A, et al. Candida auris outbreak: Mortality, interventions and cost of sustaining control. J Infect. 2019;79(6):601-11.
  • 23. Alvarado-Socarras JL, Vargas-Soler JA, Franco-Paredes C, Villegas-Lamus KC, Rojas-Torres JP, Rodriguez-Morales AJ. A Cluster of Neonatal Infections Caused by Candida auris at a Large Referral Center in Colombia. J Pediatric Infect Dis Soc. 2021;10(5):549-55.
  • 24. Kathuria S, Singh PK, Sharma C, Prakash A, Masih A, Kumar A, et al. Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method. J Clin Microbiol. 2015;53(6):1823-30. doi: 10.1128/JCM.00367-15.
  • 25. Ong CW, Chen SC, Clark JE, Halliday CL, Kidd SE, Marriott DJ, et al, Heath CH; Australian and New Zealand Mycoses Interest Group (ANZMIG); and the Healthcare Infection Control Special Interest Group (HICSIG); both of the Australasian Society for Infectious Diseases (ASID). Diagnosis, management and prevention of Candida auris in hospitals: position statement of the Australasian Society for Infectious Diseases. Intern Med J. 2019;49(10):1229-43.
  • 26. Kurt AF, Kuskucu MA, Balkan II, Baris A, Yazgan Z, Serife Oz A, Tosun AI, Mete B, Tabak F, Aygun G. Candida auris Fungemia and a local spread taken under control with infection control measures: First report from Turkey. Indian J Med Microbiol. 2021;39(2):228-30.
  • 27. Teke L, Altunok ES, Moralar DG. Mediterr J Infect Microb Antimicrob. 2021; 10: 48. Erişim: http://dx. doi. org/10.4274/mjima. galenos. 2021.2021. 48.
  • 28. Bölükbaşı Y, Erköse Genç G, Orhun G, Kuşkucu MA, Çağatay A, Önel M, et al. Türkiye’de İlk COVID-19 Pozitif Candida auris Fungemi Olgusu [First Case of COVID-19 Positive Candida auris Fungemia in Turkey]. Mikrobiyol Bul. 2021;55(4):648-55.
  • 29. Kömeç S, Karabıçak N, Ceylan AN, Gülmez A, Özalp O. Türkiye İstanbul’dan Bildirilen Üç Candida auris Olgusu [Three Candida auris Case Reports from Istanbul, Turkey]. Mikrobiyol Bul. 2021 ;55(3):452-60.

CANDIDA AURIS INFECTIONS

Year 2022, Volume: 4 Issue: 2, 124 - 131, 30.06.2022

Abstract

Candida auris is an emerging but important pathogen due to its ability to cause epidemics and antifungal resistance. This factor, which was first detected in 2009, has rapidly started to be seen globally, and there have been cases detected in our country in recent years. However, much remains unknown about this current global public health pathogen. In this review, we aimed to review the literature on C. auris.

Project Number

yok

References

  • 1. Centers for Disease Control and Prevention. Fungal Diseases. Candida auris. Tracking Candida auris. Erişim tarihi: 20 Ocak 2021. https://www.cdc.gov/fungal/candida- auris/tracking-c-auris.html.
  • 2. Moreno MV, Simian ME, Villarroel J, Fuenzalida LM, Yarad MF, Soto A, et al. Primer aislamiento de Candida auris en Chile [First isolation de Candida auris in Chile]. Rev Chilena Infectol. 2019;36(6):767-73.
  • 3. Jeffery-Smith A, Taori S K, Schelenz S, Jeffery K, Johnson E M, Borman A, et al. Candida auris: a review of the literature. Clin Microbiol Rev. 2017; 31 (1). pii:e00029-17.
  • 4. Araúz A B, Cáceres D H, Santiago E, Armstrong P, Arosamena S, Ramos C, et al. Isolation of Candida auris from 9 patients in Central America: Importance of accurate diagnosis and susceptibility testing. Mycoses. 2018; 61: 44-7. doi:10.1111/myc.12709.
  • 5. Lockhart S R, Etienne K A, Vallabhaneni S, Farooqi J, Chowdhary A, Govender N P, et al. Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses. Clin Infect Dis. 2017; 64: 134-40. doi: 10.1093/cid/ciw691.
  • 6. Public Health England (PHE): Guidance for the laboratory investigation, management and infection prevention and control for cases of Candida auris (2016, updated 2017). Erişim tarihi: 20 Ocak 2021. https://www.uptodate.com/contents/society-guideline-links-candidiasis.
  • 7. Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H . Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol.2009; 53:41–4. 8. Dimitrios P Kontoyiannis. Worldwide epidemiology and the burden of Candida auris. 13 April 2019. ECCMID 2019 Amsterdam.
  • 9. Chakrabarti A, Sood P, Rudramurthy SM, Chen S, Kaur H, Capoor M, et al. Incidence, characteristics and outcome of ICU-acquired candidemia in India. Intensive Care Med. 2015;41(2):285-95.
  • 10. Alkan Çeviker S, Günal Ö, Kılıç SS, Köksal E, Tahmaz A. Üçüncü Basamak Hastanede Sağlık Hizmeti ile İlişkili Kandidemilerin Epidemiyolojisi ve Mikrobiyolojik Özellikleri: Tek Merkez Deneyimi. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi. 2020; 7(1): 12-7.
  • 11. Cortegiani A, Misseri G, Fasciana T, Giammanco A, Giarratano A, Chowdhary A. Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris. J Intensive Care. 2018;6:69.
  • 12. de Cássia Orlandi Sardi J, Silva DR, Soares Mendes-Giannini MJ, Rosalen PL. Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options. Microb Pathog. 2018;125:116-121. doi: 10.1016/j.micpath.2018.09.014.
  • 13. Garcia-Jeldes HF, Mitchell R, McGeer A, Rudnick W, Amaratunga K, Vallabhaneni S, et al; CNISP C. auris Interest Group, Bharat A. Prevalence of Candida auris in Canadian acute care hospitals among at-risk patients, 2018. Antimicrob Resist Infect Control. 2020;9(1):82.
  • 14. Rudramurthy SM, Chakrabarti A, Paul RA, Sood P, Kaur H, Capoor MR, et al. Candida auris candidaemia in Indian ICUs: analysis of risk factors. J Antimicrob Chemother. 2017; 72:1794-801.
  • 15. Ayhancı T, Altındiş M. Hızla yayılan çoklu ilaca dirençli maya mantarı: Candida auris. Turk Hij Den Biyol Derg. 2020; 77(1): 123-36.
  • 16. Du H, Bing J, Hu T, Ennis CL, Nobile CJ, Huang G. Candida auris: Epidemiology, biology, antifungal resistance, and virulence. PLoS Pathog. 2022;16(10):e1008921. doi: 10.1371/journal.ppat.1008921.
  • 17. Pathirana RU, Friedman J, Norris HL, Salvatori O, McCall AD, Kay J, et al. Fluconazole-resistant Candida auris is susceptible to salivary histatin 5 killing and to intrinsic host defenses. Antimicrob Agents Chemother. 2018;62(2):e01872-17. doi: 10.1128/AAC.01872-17.
  • 18. Chowdhary A, Tarai B, Singh A, Sharma A. Multidrug-Resistant Candida auris Infections in Critically Ill Coronavirus Disease Patients, India, April-July 2020. Emerg Infect Dis. 2020;26(11):2694-6. doi: 10.3201/eid2611.203504.
  • 19. Villanueva-Lozano H, Treviño-Rangel RJ, González GM, Ramírez-Elizondo MT, Lara-Medrano R, Aleman-Bocanegra MC, et al. Outbreak of Candida auris infection in a COVID-19 hospital in Mexico. Clin Microbiol Infect. 2021;27(5):813–6. doi: 10.1016/j.cmi.2020.12.030.
  • 20. Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP, et al. A Candida auris Outbreak and Its Control in an Intensive Care Setting. N Engl J Med. 2018;379(14):1322-31.
  • 21. García CS, Palop NT, Bayona JVM, García MM, Rodríguez DN, Álvarez MB, et al. Candida auris: report of an outbreak. Enferm Infecc Microbiol Clin (Engl Ed). 2020;38 Suppl 1:39-44.
  • 22. Taori SK, Khonyongwa K, Hayden I, Athukorala GDA, Letters A, Fife A, et al. Candida auris outbreak: Mortality, interventions and cost of sustaining control. J Infect. 2019;79(6):601-11.
  • 23. Alvarado-Socarras JL, Vargas-Soler JA, Franco-Paredes C, Villegas-Lamus KC, Rojas-Torres JP, Rodriguez-Morales AJ. A Cluster of Neonatal Infections Caused by Candida auris at a Large Referral Center in Colombia. J Pediatric Infect Dis Soc. 2021;10(5):549-55.
  • 24. Kathuria S, Singh PK, Sharma C, Prakash A, Masih A, Kumar A, et al. Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method. J Clin Microbiol. 2015;53(6):1823-30. doi: 10.1128/JCM.00367-15.
  • 25. Ong CW, Chen SC, Clark JE, Halliday CL, Kidd SE, Marriott DJ, et al, Heath CH; Australian and New Zealand Mycoses Interest Group (ANZMIG); and the Healthcare Infection Control Special Interest Group (HICSIG); both of the Australasian Society for Infectious Diseases (ASID). Diagnosis, management and prevention of Candida auris in hospitals: position statement of the Australasian Society for Infectious Diseases. Intern Med J. 2019;49(10):1229-43.
  • 26. Kurt AF, Kuskucu MA, Balkan II, Baris A, Yazgan Z, Serife Oz A, Tosun AI, Mete B, Tabak F, Aygun G. Candida auris Fungemia and a local spread taken under control with infection control measures: First report from Turkey. Indian J Med Microbiol. 2021;39(2):228-30.
  • 27. Teke L, Altunok ES, Moralar DG. Mediterr J Infect Microb Antimicrob. 2021; 10: 48. Erişim: http://dx. doi. org/10.4274/mjima. galenos. 2021.2021. 48.
  • 28. Bölükbaşı Y, Erköse Genç G, Orhun G, Kuşkucu MA, Çağatay A, Önel M, et al. Türkiye’de İlk COVID-19 Pozitif Candida auris Fungemi Olgusu [First Case of COVID-19 Positive Candida auris Fungemia in Turkey]. Mikrobiyol Bul. 2021;55(4):648-55.
  • 29. Kömeç S, Karabıçak N, Ceylan AN, Gülmez A, Özalp O. Türkiye İstanbul’dan Bildirilen Üç Candida auris Olgusu [Three Candida auris Case Reports from Istanbul, Turkey]. Mikrobiyol Bul. 2021 ;55(3):452-60.
There are 28 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Basic Sciences
Authors

Serhat Karaayvaz 0000-0003-0048-8010

Sevil Alkan 0000-0003-1944-2477

Project Number yok
Publication Date June 30, 2022
Submission Date February 3, 2022
Published in Issue Year 2022 Volume: 4 Issue: 2

Cite

Vancouver Karaayvaz S, Alkan S. CANDIDA AURIS ENFEKSİYONLARI. Dent & Med J - R. 2022;4(2):124-31.




"The truest guide for everything in the world, for civilization, for life, for success, is science. Seeking a guide outside of science and science is heedlessness, ignorance, and deviating from the right path. It is only necessary to understand the development of science and science in every minute we live and to follow the progress in time. To attempt to apply the rules of science and science a thousand, two thousand, and thousands of years ago, today, after so many thousand years, is, of course, not to be in science and science."
M. Kemal ATATÜRK