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A MULTICYSTIC ULTRASONOGRAPHIC IMAGE OF ENDOMETRIUM IN TAMOXIFEN USE ; CASE REPORT

Year 2006, Issue: 010, 181 - 184, 15.05.2006

Abstract

Background: Tamoxifen is a nonsteroidal anti-estrogen that widely used as part of breast cancer. In addition to its anti-estrogenic properties, tamoxifen has a stimulatory effect on the endometrium. In this report we present a bizarre ultrasonographic image of endometrium in a patient receiving tamoxifen.Case: A 55 year-old postmenopausal woman gravida 4 parite 3 presented us for spotty like vaginal bleeding. She had surgery for breast cancer and took tamoxifen for two years. Pelvic examination was made, a multicystic grape like ultrasonographic image was detected.Conclusion: Early endometrial lesions can be detected by using transvaginal ultrasound in tamoxifen therapy. Oedema and enlargement of the stromal cells make different findings on the ultrasound.

References

  • [1] Cuzick J,2000. A brief review of the current breast cancer prevention trials and proposals for future trials. Eur J Cancer. 36: 1298-1302.
  • [2] Gottardis MM, Robinson SP, Satyaswaroop PG: Contrasting actions of tamoxifen on endometrial and breast tumour growth in athymic Mouse. Cancer Res 1988;48: 812-815.
  • [3] Tesoro MR, Borgida AF, MacLaurin NA, 1999. Transvaginal endometrial sonography in postmenopausal women taking tamoxifen. Obstet Gynecol. 93: 363-366.
  • [4] Archiron R, Lipitz S, Sivan E, 1995. Changes mimicking endometrial neoplasia in postmenopausal, tamoxifen treated women with breast cancer:A transvaginal doppler study. Ultrasound Obstet Gynecol. 6: 116-120.
  • [5] Goldstein SR, 1994. Unusual ultrasonographic appearence of the uterus in patients receivig tamoxifen. Am J Obstet Gynecol. 170: 447-451.

A MULTICYSTIC ULTRASONOGRAPHIC IMAGE OF ENDOMETRIUM IN TAMOXIFEN USE ; CASE REPORT

Year 2006, Issue: 010, 181 - 184, 15.05.2006

Abstract

Background: Tamoxifen is a nonsteroidal anti-estrogen that widely used as part of breast cancer. In addition to its anti-estrogenic properties, tamoxifen has a stimulatory effect on the endometrium. In this report we present a bizarre ultrasonographic image of endometrium in a patient receiving tamoxifen.Case: A 55 year-old postmenopausal woman gravida 4 parite 3 presented us for spotty like vaginal bleeding. She had surgery for breast cancer and took tamoxifen for two years. Pelvic examination was made, a multicystic grape like ultrasonographic image was detected.Conclusion: Early endometrial lesions can be detected by using transvaginal ultrasound in tamoxifen therapy. Oedema and enlargement of the stromal cells make different findings on the ultrasound.

References

  • [1] Cuzick J,2000. A brief review of the current breast cancer prevention trials and proposals for future trials. Eur J Cancer. 36: 1298-1302.
  • [2] Gottardis MM, Robinson SP, Satyaswaroop PG: Contrasting actions of tamoxifen on endometrial and breast tumour growth in athymic Mouse. Cancer Res 1988;48: 812-815.
  • [3] Tesoro MR, Borgida AF, MacLaurin NA, 1999. Transvaginal endometrial sonography in postmenopausal women taking tamoxifen. Obstet Gynecol. 93: 363-366.
  • [4] Archiron R, Lipitz S, Sivan E, 1995. Changes mimicking endometrial neoplasia in postmenopausal, tamoxifen treated women with breast cancer:A transvaginal doppler study. Ultrasound Obstet Gynecol. 6: 116-120.
  • [5] Goldstein SR, 1994. Unusual ultrasonographic appearence of the uterus in patients receivig tamoxifen. Am J Obstet Gynecol. 170: 447-451.
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Details

Primary Language English
Journal Section Research Article
Authors

Emine Coşar

Mehmet R. Helvacı This is me

Publication Date May 15, 2006
Published in Issue Year 2006 Issue: 010

Cite

APA Coşar, E., & Helvacı, M. R. (2006). A MULTICYSTIC ULTRASONOGRAPHIC IMAGE OF ENDOMETRIUM IN TAMOXIFEN USE ; CASE REPORT. Journal of Science and Technology of Dumlupınar University(010), 181-184.

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