ÜÇ FARKLI GÖRÜNTÜLEME TEKNİĞİNDEN ALINAN TİBİA ÖLÇÜMLERİNİN GÜVENİLİRLİĞİNİN DEĞERLENDİRİLMESİ

Year 2020, Volume: 60 Issue: 1, 119 - 144, 01.01.2020

Öznur Gülhan

Abstract

Antropolojik araştırmalarda özellikle de adli antropoloji çalışmalarında kullanılan bir yöntemin hata oranlarının verilmesi yapılan çalışmanın uygulanabilir olması için oldukça önemlidir. Günümüzde özellikle teknolojik gelişmelerle birlikte çok sayıda yeni yöntem geliştirilmekte ve literatüre eklenmektedir. Non-invaziv olması ve verilerin kalıcılığı gibi sebeplerden son yıllarda özellikle medikal görüntüleme teknikleri antropolojik araştırma süreçlerinde sıklıkla yararlanılan teknolojilerden biri olmaktadır. Bu sebeple bu tekniklerin kullanılmasıyla oluşturulan yeni yöntemlerin uygulanabilirliğini analiz etmek önemlidir. Ayrıca, Daubert standartları ile birlikte mahkemede kullanılan bilimsel çalışmalar için kabul edilirlik kriterlerinin oluşturulmasından bu yana adli antropologlar tarafından kullanılan yöntemler ciddi bir inceleme altına girmiştir. Bu sebeple, antropolojik araştırmalarda kullanılan biyolojik profillerin oluşturulmasında sıklıkla tercih edilen metrik ölçümlerin tekrarlanabilir ve güvenilir olmasını sağlamak önemlidir. Bu çalışmanın amacı; biyolojik profil veya popülasyon spesifik formüller oluşturmak için kullanılan metrik ölçümlerde aynı bilgisayar yazılımı içerisinde farklı görüntüleme tekniklerinden alınan tibia ölçümleri arasındaki gözlemci içi güvenilirliği analiz etmektir. Bu sebeple, bilgisayarlı tomografi görüntülerinden elde edilen 15 adet sanal tibia görüntüsü çalışmanın verisini oluşturmaktadır. OsiriX programı kullanılarak işlenen tibia görüntülerinden alınan beş adet metrik ölçüm SPSS 24.0 ve Excel yazılım paketleri kullanılarak analiz edilmiştir. Üç farklı görüntüleme tekniğinden alınan beş ölçüm ANOVA analizi kullanılarak karşılaştırılmıştır. Gözlemci içi güvenilirlik analizi için sınıf içi korelasyon katsayısı ICC kullanılmış ve gözlemci hatası TEM, rTEM ve R hesaplanarak analiz edilmiştir. Sonuç olarak tibiadan alınan metrik ölçümlerde üç farklı görüntüleme tekniği kıyaslandığında MDEB ölçümü dışında diğer dört ölçüm arasında anlamlı bir farklılık gözlenmemiştir. Bununla birlikte yalnızca hacimsel görüntülemeden alınan beş ölçümün hepsi için gözlemci içi güvenilirlik 0.998-0.948 yüksek güvenilirlik arasında değişmekte ve bu durum özellikle adli antropoloji çalışmaları için önerilen değer aralıklarını karşılamaktadır. Bu sebeple, üç görüntüleme tekniği arasında hacimsel görüntülemeden alınan ölçümlerin gözlemci içi güvenilirliği en yüksek olduğu için ileride yapılacak çalışmalarda hacimsel görüntüleme modunun tercih edilmesinin daha güvenilir sonuçlar vereceği düşünülmektedir.

Keywords

Antropoloji, Görüntüleme Teknikleri, Tibia Ölçümleri, Bilgisayarlı Tomografi, Gözlemci İçi Güvenilirlik

EVALUATION OF THE REALIABILITY OF TIBIA MEASUREMENTS FROM THREE DIFFERENT IMAGING TECHNIQUES

Abstract

The methods used in anthropological research especially in forensic anthropological investigations should have report potential error rates in order to become internationally applicable. Recently, many new methods with the advancement of technological improvements have been developed. Due to non-invasive nature, medical imaging techniques have become one of the frequently used technologies in anthropological research. Therefore, it is quite important to analyse the applicability of these new methods created using these techniques. Moreover, the methods used by forensic anthropologists have been under serious scrutiny since the creation of acceptance criteria for scientific studies that are especially used in court in order to meet Daubert standards. For this reason, it is important to ensure that the frequently preferred metric measurements are reproducible and reliable in the creation of biological profiles used in anthropological research. The aim of this study is to analyze intra-observer reliability between tibia measurements taken from different imaging techniques in the same computer software. Therefore, 15 tibia images obtained from computed tomography constitute the data of the study. Five metric measurements from tibia images processed using the OsiriX program were analyzed using SPSS 24.0 and Excel software packages. Five measurements taken from three different imaging techniques were compared using ANOVA analysis. For intraobserver reliability analysis, ICC was used and observer error was analyzed by calculating TEM, rTEM and R. As a result, when three different imaging techniques were compared in the metric measurements taken from the tibia, no significant difference was observed between the four measurements except MDEB measurement. However, for all five measurements taken from only volumetric imaging, intra-observer reliability ranges from 0.998-0.948 high reliability , which meets the recommended value ranges specifically for forensic anthropology studies. Since the measurements taken from volumetric imaging among the imaging techniques have the highest intra-observer reliability, it is thought that preferring the volumetric imaging mode in future studies will yield more reliable results.

Keywords

Anthropology, Imaging Techniques, Tibia Measurements, Computed Tomography, Intra-Observer Reliability

References

• Bernadette, M. Manifold. “Bone Mineral Density in Children From Anthropological and Clinical Sciences: A Review.” Anthropological Review 77.2 (2014): 111– 135.
• Biwasaka, Hitoshi ve diğerleri. “Analyses of Sexual Dimorphism of Reconstructed Pelvic Computed Tomography Images of Contemporary Japanese Using Curvature of the Greater Sciatic Notch, Pubic Arch and Greater Pelvis.” Forensic Science International 219.1-3 (2012): 288.e1-288.e8. Web. 14 Aralık 2019.
• Böni, Thomas, Frank Ruhli ve Rethy K. Chhem. “History of Paleoradiology: Early Published Literature, 1896-1921.” Canadian Association of Radiologists 55.4 (2004): 203-210. Web. 19 Mayıs 2019.
• Brenner, David J. “Should We Be Concerned about the Rapid Increase in CT Usage?” Reviews on Environmental Health 25.1 (2010): 63–68.
• Brook, Olga R. ve diğerleri. “CT Scout View as an Essential Part of CT Reading.” Australasian Radiology 51.3 (2007): 211–217.
• Brough, Alison L. ve diğerleri. “Anthropological Measurement of the Juvenile Clavicle Using Multi‐Detector Computed Tomography—Affirming Reliability.” Journal of Forensic Sciences 58.4 (2013): 946–951.
• --. “Post-Mortem Computed Tomography and 3D Imaging: Anthropological Applications for Juvenile Remains.” Forensic Science, Medicine, and Pathology 8.3 (2012): 270–279.
• Buikstra, Jane E. ve Dougles Ubelaker. Standards for Data Collection from Human Skeletal Remains. Arkansas Archeological Survey Research Series, 1994.
• Calhoun, Paul S. ve diğerleri. “Three-Dimensional Volume Rendering of Spiral CT Data: Theory and Method 1.” Radiographics 19.3 (1999): 745–764.
• Cavalcanti, Marcelo ve Michael Vannier. “Quantitative Analysis of Spiral Computed Tomography for Craniofacial Clinical Applications.” Dento Maxillo Facial Radiology 27.6 (1998): 344–350.
• Cavalcanti, Marcelo ve diğerleri. “Craniofacial Measurements Based on 3D-CT Volume Rendering: Implications for Clinical Applications.” British Institute of Radiolog 33.3 (2004): 170-176.
• Chiba, Fumiko ve diğerleri. “Age Estimation by Quantitative Features of Pubic Symphysis Using Multidetector Computed Tomography.” International Journal of Legal Medicine 128.4 (2014): 667-673.
• Clavero, Ana ve diğerleri.“Sex Prediction from the Femur and Hip Bone Using a Sample of CT Images from a Spanish Population.” International Journal of Legal Medicine 129.2 (2015): 373–383.
• Corron, Louise ve diğerleri. “Evaluating the consistency, repeatability, and reproducibility of osteometric data on dry bone surfaces, scanned dry bone surfaces, and scanned bone surfaces obtained from living individuals.” Bulletins et Memoires de La Societe d’Anthropologie de Paris 29.1-2 (2017): 33- 53.
• Decker, Summer J. ve diğerleri. “Virtual Determination of Sex: Metric and Nonmetric Traits of the Adult Pelvis from 3D Computed Tomography Models*,* .” Journal of Forensic Sciences 56.5 (2011): 1107–1114.
• Dedouit, Fabrice ve diğerleri. “New Identification Possibilities with Postmortem Multislice Computed Tomography.” International Journal of Legal Medicine 121. 6 (2007): 507–510.
• --. “Virtual Anthropology and Forensic Identification Using Multidetector CT.” The British Journal of Radiology 87.1036 (2014): 1-12.
• Fradella, Henry F. ve diğerleri. “The Impact of Daubert on the Admissibility of Behavioral Science Testimony.” Pepperdine Law Review 30.2 (2003): 403–444.
• Franklin, Daniel ve diğerleri. “Morphometric Analysis of Pelvic Sexual Dimorphism in a Contemporary Western Australian Population.” International Journal of Legal Medicine 128.5 (2014): 861–872.
• Giurazza, Francesco ve diğerleri. “Stature Estimation from Scapular Measurements by CT Scan Evaluation in an Italian Population.” Legal Medicine 15.4 (2013): 202-208.
• Grabherr, Silke ve diğerleri.“Estimation of Sex and Age of ‘Virtual Skeletons’–a Feasibility Study.” European Radiology 19.2 (2009): 419-429.
• --.“Post-Mortem Imaging in Forensic Investigations: Current Utility, Limitations, and Ongoing Developments.” Research and Reports in Forensic Medical Science 6 (2016): 25-37.
• Greiner, Philippe ve diğerleri. “Computed Tomography Evaluation of the Femoral and Tibial Attachments of the Posterior Cruciate Ligament in Vitro.” Knee Surgery, Sports Traumatology, Arthroscopy 19.11 (2011):1876-1883.
• Guenoun, Benjamin ve diğerleri. “Reliability of a New Method for Lower-Extremity Measurements Based on Stereoradiographic Three-Dimensional Reconstruction.” Orthopaedics & Traumatology: Surgery & Research 98.5 (2012): 506–513.
• Gülhan, Öznur. “Antropolojide Non-Invaziv Görüntüleme Yöntemleri.” Antropoloji 38 (2019): 79–93.
• --. “Pelvis’ten Radyolojik Yöntemler İle Cinsiyet Tayini: Türkiye Örneklemi.” Antropoloji 36 (2018): 53–69.
• Gülhan, Öznur, Karl Harrison ve Adem Kiris. “A New Computer-Tomography-Based Method of Sex Estimation: Development of Turkish Population-Specific Standards.” Forensic Science International 255 (2015): 2-8.
• Haglund, William D. ve Marcella H. Sorg. Advances in Forensic Taphonomy: Method, Theory, and Archaeological Perspectives. Boca Raton,FL:CRC Press, 2010.
• Harma, Ahmet ve Hakki Muammer Karakas. “Determination of Sex from the Femur in Anatolian Caucasians: A Digital Radiological Study.” Journal of Forensic and Legal Medicine 14.4 (2007): 190-194.
• Hildebolt, Charles F. ve diğerleri. “Validation Study of Skull Three‐dimensional Computerized Tomography Measurements.” American Journal of Physical Anthropology 82.3 (1990): 283-294.
• Hishmat, Asmaa Mohammed ve diğerleri. “Virtual CT Morphometry of Lower Limb Long Bones for Estimation of the Sex and Stature Using Postmortem Japanese Adult Data in Forensic Identification.” International Journal of Legal Medicine 129.5 (2015): 1173-1182.
• Hİyer, Christian Bjerre ve diğerleri. “Investigation of a Fatal Airplane Crash: Autopsy, Computed Tomography, and Injury Pattern Analysis Used to Determine Who Was Steering the Plane at the Time of the Accident. A Case Report.” Forensic Science, Medicine, and Pathology 8.2 (2012): 179-188.
• Ishak, Nur-Intaniah ve diğerleri. “Estimation of Stature from Hand and Handprint Dimensions in a Western Australian Population.” Forensic Science International 216.1 (2012): 199.e1-199.e7. Web. 25 Ekim 2019.
• Kieser, Julius A. Human Adult Odontometrics:the study of variation in adult tooth size. Cambridge: Cambridge University Press, 1990.
• Kim, Dong Kyu ve diğerleri. “Method of Individual Adjustment for 3D CT Analysis: Linear Measurement.” BioMed Research International 2016 (2016): 1-9.
• Kim, Gihyeon ve diğerleri. “Accuracy and Reliability of Length Measurements on Three-Dimensional Computed Tomography Using Open-Source OsiriX Software.” Journal of Digital Imaging 25.4 (2012): 486-491.
• Kjellberg, Martin ve diğerleri. “Measurement of Leg Length Discrepancy after Total Hip Arthroplasty. the Reliability of a Plain Radiographic Method Compared to CT-Scanogram.” Skeletal Radiology 41.2 (2012): 187–191.
• Koo, Terry K. ve Mae Y. Li. “A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research.” Journal of Chiropractic Medicine 15.2 (2016):155-163.
• Kullmer, Ottmar. “Benefits and Risks in Virtual Anthropology.” Journal of Anthropological Sciences 86 (2008): 205–207.
• Lesciotto, Kate M. “The Impact of Daubert on the Admissibility of Forensic Anthropology Expert Testimony.” Journal of Forensic Sciences 60. 3 (2015): 549–555.
• Lottering, Nicolene ve diğerleri. “Introducing Standardized Protocols for Anthropological Measurement of Virtual Subadult Crania Using Computed Tomography.” Journal of Forensic Radiology and Imaging 2.1 (2014): 34-38.
• Martin, Rudolf. Lehrbuch der Anthropologie. Jena:Verlag von Gustav Fischer,1928. Web. 1 Ekim 2019.
• Melissano, G. ve diğerleri. “Demonstration of the Adamkiewicz Artery by Multidetector Computed Tomography Angiography Analysed with the Open- Source Software OsiriX.” European Journal of Vascular and Endovascular Surgery 37.4 (2009): 395–400.
• Middleham, Helen P. ve diğerleri. “Sex Determination from Calcification of Costal Cartilages in a Scottish Sample.” Clinical Anatomy 28.7 (2015): 888–895.
• Minier, Marie ve diğerleri. “Fetal Age Estimation Using MSCT Scans of the Mandible.” International Journal of Legal Medicine 128.3 (2014): 493-499.
• Mongle, Carrie S., Ian J. Wallace ve Frederick E. Grine. “Cross-Sectional Structural Variation Relative to Midshaft along Hominine Diaphyses. II. the Hind Limb.” American Journal of Physical Anthropology 158.3 (2015): 398–407.
• Qiang, Minfei ve diğerleri. “Measurement of Three-Dimensional Morphological Characteristics of the Calcaneus Using CT Image Post-Processing.” Journal of Foot and Ankle Research 7.1 (2014): 7-19.
• Ramsthaler, Frank ve diğerleri. “Digital Forensic Osteology: Morphological Sexing of Skeletal Remains Using Volume-Rendered Cranial CT Scans.” Forensic Science International 195.1 ( 2010):148–152.
• Robinson, Claire ve diğerleri.“Anthropological Measurement of Lower Limb and Foot Bones Using Multi‐Detector Computed Tomography.” Journal of Forensic Sciences 53.6 (2008):1289–1295.
• Rutty, Guy Nathan ve diğerleri. “The Role of Micro-Computed Tomography in Forensic Investigations.” Forensic Science International 225.1-3 (2013):60-66.
• Sabharwal, Sanjeev ve diğerleri. “Computed Radiographic Measurement of Limb- Length Discrepancy. Full-Length Standing Anteroposterior Radiograph Compared with Scanogram.” The Journal of Bone and Joint Surgery 88.10 (2006): 2243–2251.
• Sapse, Danielle ve Lawrence Kobilinsky. Forensic Science Advances and Their Application in the Judiciary System. Boca Raton,FL:CRC Press, 2011.
• Schmeling, Andreas. “Age Estimation in the Living: Imaging and Age Estimation.” Encyclopedia of Forensic and Legal Medicine, Ed. Roger Byard ve Jason Payne- James. London: Elsevier Academic (2015): 70–78.
• Spake, Laure ve diğerleri. “A Simple and Software-Independent Protocol for the Measurement of Post-Cranial Bones in Anthropological Contexts Using Thin- Slab Maximum Intensity Projection.” Forensic Imaging (2020): 200354. Web. 25 Şubat 2020.
• Spoor, Fred ve diğerleri. “Using Diagnostic Radiology in Human Evolutionary Studies.” Journal of Anatomy 197.1 (2000): 61-76.
• Steyn, M. ve diğerleri. “An Assessment of the Repeatability of Pubic and Ischial Measurements.” Forensic Science International 214.1-3 (2012): 210.e1-210.e4. Web. 8 Eylül 2019.
• Stomfai, S. ve diğerleri. “Intra-and Inter-Observer Reliability in Anthropometric Measurements in Children.” International Journal of Obesity 35 (2011): 45–51. Web. 19 Ekim 2019.
• Stull, Kyra E. ve diğerleri.“Accuracy and Reliability of Measurements Obtained from Computed Tomography 3D Volume Rendered Images.” Forensic Science International 238 (2014):133-140.
• Tersigni-Tarrant, MariaTeresa A. ve Natalie R. Shirley. Forensic Anthropology : An Introduction. Boca Raton,FL:CRC Press, 2013.
• Thompson, Tim. ve Sue Black. Forensic Human Identification: An Introduction. Boca Raton, FL:CRC Press, 2006.
• Torimitsu, Suguru ve diğerleri. “Morphometric Analysis of Sex Differences in Contemporary Japanese Pelves Using Multidetector Computed Tomography.” Forensic Science International 257 (2015): 530.e1-530.e7. Web. 1 Eylül 2018.
• Uldin, Tanya. “Virtual Anthropology – a Brief Review of the Literature and History of Computed Tomography.” Forensic Sciences Research 2.4 (2017): 165–173. Web. 1 Ekim 2019.
• Vaidya, Rahul ve diğerleri. “CT Scanogram for Limb Length Discrepancy in Comminuted Femoral Shaft Fractures Following IM Nailing.” Injury 43.7 (2012): 1176-1181.
• Verhoff, Marcel A. ve diğerleri. “Digital Forensic Osteology—Possibilities in Cooperation with the Virtopsy® Project.” Forensic Science International 174.2 (2008): 152–156.
• Villa, Chiara ve diğerleri. “Evaluating Osteological Ageing from Digital Data.” Journal of Anatomy 235.2 (2016): 386–395.
• Weinberg, Seth M. ve diğerleri. “Intraobserver Error Associated with Measurements of the Hand.” American Journal of Human Biology 17.3 (2005): 368-371.
• Zhang, Kui ve diğerleri. “Sexual Dimorphism of Sternum Using Computed Tomography – Volume Rendering Technique Images of Western Chinese.” Australian Journal of Forensic Sciences 48. 3 (2016): 297–304.