Vücut Kitle İndeksinin Trombosit Aferez Donörlerinin Trombosit Sayıları ve Donasyon Sıklığı ile İlişkisi

Year 2022, , 90 - 94, 30.04.2022

Sevil Sadri , Hülya Bilgen

https://doi.org/10.18678/dtfd.1058458

Cited By: 1

Abstract

Amaç: Bu çalışmanın amacı, koronavirüs hastalığı 2019 (coronavirus disease 2019, COVID-19) pandemi döneminde trombosit aferez donörlerinin demografik özelliklerinin araştırılması, trombosit sayılarının kan grupları ve vücut kitle indeksi (VKİ) ile ilişkisinin gözden geçirilmesi ve VKİ’nin trombosit aferez bağışı üzerindeki etkisini karakterize etmektir.
Gereç ve Yöntemler: Bu geriye dönük çalışmada Ocak 2020 ve Ocak 2021 tarihleri arasında merkezimize başvuran trombosit aferez donörlerinin demografik özellikleri incelendi ve hemogram parametreleri, daha önceki trombosit bağış sıklığı ve kan grubu bilgileri kaydedildi. Bağışçıların trombosit sayıları, kan grupları ve VKİ arasındaki ilişki analiz edildi.
Bulgular: Trombosit sayıları ile kan grupları arasında istatistiksel olarak anlamlı bir ilişki bulunmamıştır. Trombosit sayıları Rh pozitif bağışçılarda daha yüksek olmakla birlikte trombosit sayıları ile Rh grubu arasında istatistiksel olarak anlamlı bir ilişki bulunmamıştır (p=0,675). Düşük kilolu donörlerde trombosit sayıları daha düşük olsa da trombosit sayısı ile VKİ grupları arasında istatistiksel olarak anlamlı bir ilişki yoktu (p=0,134). Obez grup ile karşılaştırıldığında, normal kilolu gruptaki daha düşük trombosit torba sayısı istatiksel olarak anlamlı olarak bulundu (p=0,001). Normal kilolu ve obez gruplara göre daha fazla sayıda olan, fazla kilolu gruba yapılan bağış sayısı istatistiksel olarak anlamlı olduğu bulundu (p=0,002).
Sonuç: Trombosit sayısı obezite ile birlikte artsa da bu durum sağlıklı trombosit donörlerde istatiksel olarak bir anlamlılığa sahip değildir. Sonuç olarak, obezitenin trombosit aferez bağışı ile ters bir ilişkisi yoktur ve yüksek VKİ bağış için prognostik bir faktör olarak kabul edilmemelidir.

Keywords

trombosit aferez, donör, vücut kitle indeksi

The Relationship of Body Mass Index with Platelet Counts and Donation Frequency of Platelet Apheresis Donors

Abstract

Aim: The aim of this study was to investigate the demographic characteristics of platelet apheresis donors during the coronavirus disease 2019 (COVID-19) pandemic, to examine the association of platelet counts with blood groups and body mass index (BMI), and to characterize the effects of BMI on platelet apheresis donation.
Material and Methods: In this retrospective study, the demographic characteristics of platelet apheresis donors admitted to our center between January 2020 and January 2021 were examined, and hemogram parameters, previous platelet donation frequencies, and blood groups information were recorded. The relationship between donors' platelet counts, blood groups, and BMI were analyzed.
Results: There was no statistically significant relationship between the platelet counts and blood groups. Although platelet counts were higher in Rh positive donors, no statistically significant relationship was found between platelet counts and the Rh group (p=0.675). Even though the platelet counts were lower in low-weight donors, there was no statistically significant relationship between platelet count and BMI groups (p=0.134). The lower collected platelet counts of the normal group, compared to the obese group, was found to be statistically significant (p=0.001). The number of donations for the overweight group being higher than the normal and obese groups was found to be statistically significant (p=0.002).
Conclusion: Even though the platelet count increases with obesity, it does not have any statistical significance in healthy platelet donors. In conclusion, obesity does not have an inverse relationship with platelet apheresis donation and high BMI should not be considered as a prognostic factor for donation.

Keywords

platelet, apheresis, donors, body mass index

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