Diagnosis and Treatment Approaches in Vaginal Agenesis

Year 2024, , 91 - 94, 30.08.2024

Alper Başbuğ

https://doi.org/10.18678/dtfd.1531224

Abstract

The development of the female genital system is a complex process that depends on a series of events involving cellular differentiation, migration, fusion, and recanalization. Failure of any of these processes results in congenital anomalies. Developmental anomalies can occur at various stages, resulting in conditions that impact both the urinary and reproductive systems. In younger patients, such malformations can significantly affect their overall health and quality of life, including aspects such as fertility, sexual function, and psychological well-being. The psychosexual effects of vaginal agenesis should not be overlooked, and clinical care primarily involves comprehensive counseling and support through open communication with the patient. For adult patients, treatment for vaginal agenesis typically starts with therapeutic counseling and education, with non-invasive vaginal dilation being recommended as the first-line approach, or surgery if necessary. Consequently, managing these issues often requires a multidisciplinary approach, engaging specialists such as urologists, gynecologists, endocrinologists, and geneticists, among others. Early detection and timely intervention can greatly enhance the outlook for individuals with these conditions. Besides considering the patient's expectations, the surgeon's experience plays a crucial role in selecting the appropriate surgical technique. This is because the success of the initial surgery is critical to the effectiveness of any subsequent procedures if required. In this review, the evaluation and treatment of vaginal agenesis, which constitutes an important part of congenital anomalies of the vagina, were discussed.

Keywords

Müllerian canal, vaginal agenesis, vaginoplasty

Vajinal Agenizde Tanı ve Tedavi Yaklaşımları

Abstract

Kadın genital sisteminin gelişimi, hücresel farklılaşma, göç, füzyon ve yeniden kanalizasyonu içeren bir dizi olaya bağlı olan karmaşık bir süreçtir. Bu süreçlerden herhangi birinin başarısızlığı doğumsal anomalilerle sonuçlanır. Gelişimsel anomaliler çeşitli aşamalarda ortaya çıkabilir ve hem üriner hem de üreme sistemlerini etkileyen durumlarla sonuçlanabilir. Genç hastalarda, bu tür malformasyonlar doğurganlık, cinsel işlev ve psikolojik refah gibi hususlar da dahil olmak üzere genel sağlıklarını ve yaşam kalitelerini önemli ölçüde etkileyebilir. Vajinal agenezinin psikoseksüel etkileri göz ardı edilmemelidir ve klinik bakım öncelikle hastayla açık iletişim yoluyla kapsamlı danışmanlık ve desteği içerir. Yetişkin hastalar için vajinal agenezi tedavisi tipik olarak terapötik danışmanlık ve eğitimle başlar, ilk basamak yaklaşım olarak invazif olmayan vajinal dilatasyon veya gerekirse cerrahi önerilir. Sonuç olarak, bu sorunların yönetimi genellikle ürologlar, jinekologlar, endokrinologlar ve genetikçiler gibi uzmanları içeren multidisipliner bir yaklaşım gerektirir. Erken teşhis ve zamanında müdahale, bu durumlara sahip bireylerin görünümünü büyük ölçüde iyileştirebilir. Hastanın beklentilerini göz önünde bulundurmanın yanı sıra, cerrahın deneyimi de uygun cerrahi tekniğin seçilmesinde çok önemli bir rol oynar. Bunun nedeni, ilk ameliyatın başarısının, gerekirse sonraki prosedürlerin etkinliği açısından kritik olmasıdır. Bu derlemede, vajinanın konjenital anomalilerinin önemli bir bölümünü oluşturan vajinal agenezinin değerlendirilmesi ve tedavisi tartışılmıştır.

Keywords

Müllerian kanal, vajinal agenezi, vajinoplasti

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