Primary Localized Amyloidosis of the Nasopharynx: A Case Report

Deniz Baklacı; Oğuz Can Karakaş; Aleyna Şivetoğlu; Filiz Kutlu

doi:10.18678/dtfd.1865876

Primary Localized Amyloidosis of the Nasopharynx: A Case Report

Abstract

Amyloidosis is characterized by the extracellular deposition of abnormally folded proteins. While localized forms occur in the head and neck, nasopharyngeal involvement is rare and can mimic malignancies.
We present a rare case of primary localized nasopharyngeal amyloidosis. A 67-year-old female presented with nasal congestion, throat lump sensation, and left-sided conductive hearing loss. Endoscopy revealed a yellow-colored mass in the left nasopharynx. MRI showed a homogeneously enhancing lesion without destruction. Diagnosis was confirmed by histopathology demonstrating apple-green birefringence with Congo red staining. Systemic amyloidosis was excluded through comprehensive evaluation. The patient was managed with close follow-up, and no progression was observed over five years.
Nasopharyngeal amyloidosis should be considered in the differential diagnosis of nasopharyngeal masses. Histopathological confirmation is essential, and systemic involvement must be meticulously excluded.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Case Report

Authors

Deniz Baklacı
0000-0001-8449-4965
Türkiye

Oğuz Can Karakaş
0009-0004-5642-5582
Türkiye

Aleyna Şivetoğlu ^*
0009-0006-7262-181X
Türkiye

Filiz Kutlu
0000-0003-1743-457X
Türkiye

Publication Date

August 21, 2026

Submission Date

January 19, 2026

Acceptance Date

June 1, 2026

Published in Issue

Year 2026 Volume: 28 Number: 2

DOI

https://doi.org/10.18678/dtfd.1865876

IZ

https://izlik.org/JA76EL83NX

Cite

RIS / Bibtex

APA

Baklacı, D., Karakaş, O. C., Şivetoğlu, A., & Kutlu, F. (2026). Primary Localized Amyloidosis of the Nasopharynx: A Case Report. Duzce Medical Journal, 28(2), 221-225. https://doi.org/10.18678/dtfd.1865876

AMA

1.Baklacı D, Karakaş OC, Şivetoğlu A, Kutlu F. Primary Localized Amyloidosis of the Nasopharynx: A Case Report. Duzce Med J. 2026;28(2):221-225. doi:10.18678/dtfd.1865876

Chicago

Baklacı, Deniz, Oğuz Can Karakaş, Aleyna Şivetoğlu, and Filiz Kutlu. 2026. “Primary Localized Amyloidosis of the Nasopharynx: A Case Report”. Duzce Medical Journal 28 (2): 221-25. https://doi.org/10.18678/dtfd.1865876.

EndNote

Baklacı D, Karakaş OC, Şivetoğlu A, Kutlu F (August 1, 2026) Primary Localized Amyloidosis of the Nasopharynx: A Case Report. Duzce Medical Journal 28 2 221–225.

IEEE

[1]D. Baklacı, O. C. Karakaş, A. Şivetoğlu, and F. Kutlu, “Primary Localized Amyloidosis of the Nasopharynx: A Case Report”, Duzce Med J, vol. 28, no. 2, pp. 221–225, Aug. 2026, doi: 10.18678/dtfd.1865876.

ISNAD

Baklacı, Deniz - Karakaş, Oğuz Can - Şivetoğlu, Aleyna - Kutlu, Filiz. “Primary Localized Amyloidosis of the Nasopharynx: A Case Report”. Duzce Medical Journal 28/2 (August 1, 2026): 221-225. https://doi.org/10.18678/dtfd.1865876.

JAMA

1.Baklacı D, Karakaş OC, Şivetoğlu A, Kutlu F. Primary Localized Amyloidosis of the Nasopharynx: A Case Report. Duzce Med J. 2026;28:221–225.

MLA

Baklacı, Deniz, et al. “Primary Localized Amyloidosis of the Nasopharynx: A Case Report”. Duzce Medical Journal, vol. 28, no. 2, Aug. 2026, pp. 221-5, doi:10.18678/dtfd.1865876.

Vancouver

1.Deniz Baklacı, Oğuz Can Karakaş, Aleyna Şivetoğlu, Filiz Kutlu. Primary Localized Amyloidosis of the Nasopharynx: A Case Report. Duzce Med J. 2026 Aug. 1;28(2):221-5. doi:10.18678/dtfd.1865876