Oral Mucosal Manifestation in Patients with Diabetes Mellitus

Abstract

Purpose: The purpose of this study was to compare diabetic and nondiabetic subjects regard tooral manifestation such as oral mucosal lesions, burning mouth syndrome, xerostomia, and tastechange.Material and methods: A total of 120 patients (40 with type 1 diabetes mellitus, 40 type 2diabetes mellitus and 40 control groups) were examined for oral mucosal lesions, burning mouthsyndrome, xerostomia, and taste change. A self-administered questionnaire was administered.Results: The diabetic group exhibited significantly higher prevalence and more severe drymouth, taste change, tongue coating, burning mouth syndrome and mucosa pain than thenondiabetic group. The prevalence of dry mouth was 27.5% in the control group, 70% in thetype 2 diabetic group and 67.5% in type 1diabetic group. The prevalence of taste change was5% in the control group, 67.5% in the type 2 diabetic group and 22.5% in type 1diabetic group.The prevalence of mucosa pain was 30% in the type 2 diabetic group and 12.5% in type 1diabeticgroup. The prevalence of tongue coating was 5% in the control group, 52.5% in the type 2diabetic group and 30% in type 1diabetic group. The prevalence of burning mouth syndromewas 2.5% in the control group, 42.5% in the type 2 diabetic group and 35% in type 1diabeticgroup. Conclusions: This study reveals that diabetic patients exhibited a potentially higher risk for drymouth, taste change, tongue coating, burning mouth syndrome and mucosa pain

Keywords

• Diabetes mellitus,oral manifestation,burning mouth syndrome

Diyabetes Mellitus Olgularında Oral Mukoza Bulguları

Abstract

Amaç: Bu çalışmanın amacı diyabetik ve diyabetik olmayan bireylerin oral mukozal lezyonlar,ağız yanma (burning mouth) sendromu, tat değişikliği, ağız kuruluğu gibi oral bulgularınkaydedilerek karşılaştırılmasıydı.Gereç ve Yöntem: Toplam 120 hasta ( 40 tip 1 DM, 40 tip 2 DM ve 40 kontrol grubu) oralmukozal lezyonlar, burning mouth sendromu, tat değişikliği, ağız kuruluğu için muayene edildi.Form yöneltildi.Bulgular: Diyabetik grup diyabetik olmayan gruptan daha şiddetli ve yüksek prevalansta tatdeğişikliği, ağız kuruluğu, mukozada ağrı, dilde tabaka ve burning mouth sendromu sergilediler.Ağız kuruluğu prevalansı kontrol grubunda %27.5, tip 2 diyabetlilerde %70, tip 1diyabetlilerde%67.5 idi. Tat değişikliği prevalansı kontrol grubunda %5, tip 2 diyabetlilerde %67.5, tip1diyabetlilerde %22.5 idi. Mukozal ağrı prevalansı tip 2 diyabetlilerde %30, tip 1diyabetlilerde%12.5 idi. Dilde tabaka prevalansı kontrol grubunda %5, tip 2 diyabetlilerde %52.5, tip1diyabetlilerde 30% idi. Burning mouth sendromu prevalansı kontrol grubunda %2.5, tip 2diyabetlilerde %42.5, tip 1diyabetlilerde %35 idi.Sonuçlar: Bu çalışma diyabetik hastaların ağız kuruluğu, tat değişikliği, dilde tabaka, burningmounth sendromu ve mukozal ağrıda yüksek potansiyele sahip olduğunu göstermiştir

Keywords

• Diyabetes Melllitus,oral bulgular,ağız yanma sendromu

References

1. İliçin G, Biberoğlu K, Süleymanlar G, Ünal S: İç Hastalıkları Cilt 2, Sıhhiye-Ankara. Güneş Kitap Evi. pp: 2279-2331, 2003.
2. Vernillo AT: Diabetes mellitus: Relevance to dental treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91: 263- 270, 2001.
3. Dodds MW, Dodds A: Effects of glycemic control on saliva flow rates and protein composition in non-insulin-dependent diabetes mellitus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83:465-7, 1997.
4. Manfredi M, McCullough MJ, Vescovi P, Al-Kaaravi ZM, Porter SR: Update on diabetes mellitus and related oral diseases. Oral Diseases 10: 187-200, 2004.
5. Rees D. T: The diabetic dental patient. Dental Clinics of North America 38: 447-463, 1994.
6. Scully C, Cawson A R: Medical Problems in Dentistry. Cornwall. Butterworth-Heinemann Ltd. pp:274-279, 1995.
7. Committee Report. Report of the Expert Commitee on the Diognosis and Classification of Diabetes Mellitus. Diabetes Care 26: 5-20, 2003.
8. Diagnosis and Classification of Diabetes Mellitus. American Diabetes Association. Diabetes Care 28:37-42, 2005.

9. Ataoğlu S, Yazıcı S, Yıldız Ö: Diabetes Mellitusun Erken Döneminde Sınırlı Eklem Hareket Kısıtlılığının Belirlenmesi. Düzce Tıp Dergisi 2:20-26, 2004.
10. Munroe CO: The dental patient and diabetes mellitus. Dental Clinics of North America 27: 329-340, 1983..
11. Ryan DE, Bronstein SL: Dentistry and the diabetic patient. Dent Clin North Am. 26:105-18, 1982.
12. Little JW, Falace DA, Miller CS, Rhodus NL: Dental management of the medically compromised patient. St. Louis. Mosby. pp: 248-270, 2002.
13. Ponte E, Tabaj D, Maglione M, Melato M: Diabetes mellitus and oral disease. Acta Diabetol. 38: 57-62, 2001.
14. Moore PA, Guggenheimer J, Orchard T: Burning mouth and peripheral neuropathy in patients with type 1 diabetes mellitus. J Diabetes and Its Complications 21:397-402, 2007.
15. Moore PA, Guggenheimer J, Etzel KR, Weyant RJ, Orchard T: Type 1 diabetes mellitus, xerostomia, and salivary flow rates. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92: 281-291, 2001.
16. Rees TD. Periodontal management of the patient with diabetes mellitus. Periodontol. 23: 63-72, 2000.
17. Collin HL, Niskanen L, Uusitupa M, Töyry J, Collin P, Koivisto AM, Viinamäki H, Meurman JH: Oral symptoms and signs in elderly patients with type 2 diabetes mellitus. A focus on diabetic neuropathy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 90: 299-305, 2000.
18. Sandberg GE, Sundberg HE, Fjellstrom CA, Wikblad KF: Type 2 diabetes and oral health: A comparison between diabetic and non-diabetic subjects. Diabetes Res Clin Pract. 50: 27-34, 2000.
19. Grushka M, Sessle BJ: Burning mouth syndrome. Dent Clin North Am. 35: 171-84, 1991.
20. Mott AE, Grushka M, Sessle BJ: Diagnosis and management of taste disorders and burning mouth syndrome. Dent Clin North Am. 37: 33-71, 1993.
21. Grushka M, Epstein JB, Gorsky M: Burning mouth syndrome: differential diagnosis.Dermatologic Therapy 15: 287-291, 2002.