Restless Leg Syndrome in Patients on Hemodialysis Around Rize

Abstract

Aim: Our aim was to determine the prevalence of restless leg syndrome (RLS) in patients onhemodialysis in Rize and to compare the demographic and biochemical characteristics in patientswith and without RLS.Method: We enrolled all the patients over 18 years of age who were on hemodialysis for atleast three months between April and June 2014 in five dialysis centers in Rize. RLS patients’diagnoses were confirmed using the The International Restless Legs Syndrome Study Group(IRLSSG) criteria. Age, duration of hemodialysis, presence of diabetes, hemoglobin andhematocrit values, serum levels of urea, creatinine, sodium, potassium, calcium, phosphor,glucose, albumin, uric acid, iron, iron binding capacity, ferritin, and parathyroid hormone (PTH)were recorded.Results: 148 patients (43,2% female) were included in this study. The mean age of patients was61.00 ± 14,9 years . The mean duration of hemodialysis was 49,47 ± 67,3 months (4552). RLS was detected in 50 patients (33,7%). While the ratio of patients with diabetes was58% in RLS group, this ratio was 32,7% in RLS negative group (p= 0.003). Levels of fastingplasma glucose were significantly different in the two groups (151,40 ± 81.81 vb 116,00 ± 57.22,p= 0.003). While 58% of patients with RLS were female, this ratio was 35,7% in patients withoutRLS (p= 0.014). PTH, C-reactive protein, calcium, phosphorus, albumin, iron, iron bindingcapacity and ferritin levels were similar in the two groups.Conclusion: We found a 33.7% prevalence of RLS in patients receiving hemodialysis treatmentand the ratio of diabetes and female genderwere higher in patients with RLS

Keywords

• Restless leg syndrome,hemodialysis

RİZE BÖLGESİNDE HEMODİYALİZE GİREN HASTALARDA HUZURSUZ BACAK SENDROM SIKLIĞI VE İLİŞKİLİ FAKTÖRLER

Abstract

Amaç: Çalışmanın amacı; Rize ilinde hemodiyalize giren hastalarda Huzursuz bacak sendromu(HBS) sıklığını saptamak ve HBS olan ve olmayan hastalar arasındaki demografik vebiyokimyasal göstergeleri karşılaştırmaktır.Yöntem: Bu çalışmaya Nisan-Haziran 2014 tarihleri arasında Rize ve ilçelerinde bulunan 5hemodiyaliz merkezinde en az üç aydır hemodiyalize giren 18 yaş üstündeki tüm hemodiyalizhastaları alındı. HBS tanısı için uluslararası HBS çalışma grubu (The International RestlessLegs Syndrome Study Group) tarafından belirlenen tanı kriterleri kullanıldı Hastaların yaşı,diyaliz tedavi süreleri, diyabet varlığı, hemoglobin, hematokrit, serum üre, kreatinin, sodyum,potasyum, kalsiyum, fosfor, glukoz, albümin, ürik asit, demir, total demir bağlama kapasitesi,ferritin ve parathormon düzeyleri kaydedildi.Bulgular: Çalışmaya 64’ü kadın (% 43,2) toplam 148 hasta dâhil edildi. Hastaların ortalamayaşı 61.00 ± 14,9 yıldı . Ortalama hemodiyaliz süresi 49,47 ± 67,3 aydı (4-552 ay). 50(% 33,7) hastada HBS saptandı. HBS olan grupta diyabetik hasta oranı % 58 iken, olmayangrupta bu oran % 32,7 idi (p= 0.003). Açlık kan şekeri seviyeleri de iki grup arasında anlamlıfarklılık gösteriyordu (151,40 ± 81.81’ e 116,00 ± 57.22, p= 0.003).HBS olan hastaların % 58’ikadın iken HBS olmayan grupta bu oran % 35,7 olarak bulundu (p= 0.014). Parathormon, Creaktif protein, kalsiyum, fosfor, albümin, demir, ferritin ve transferrinsaturasyonu oranları heriki grupta benzerdi.Sonuç: Bu çalışmada hemodiyalize giren hastalarda HBS sıklığı %33.7 olarak saptandı vediyabet ve kadın cinsiyet oranı HBS olan grupta daha fazlaydı

Keywords

• Huzursuz bacak sendromu,hemodiyaliz

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