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Retrospective analysis of 60 patients treated with ectopic pregnancy

Year 2007, Volume: 9 Issue: 1, 4 - 7, 01.03.2007

Abstract

Purpose: The aim of this study was to review the management strategies of our clinic for ectopic pregnancies. Methods: Demographical features and treatment modalities of sixty patients diagnosed with ectopic pregnancy between January 2002 and December 2006 were reviewed retrospectively. Results: Forty-one percent of the patients had one or more spontaneous abortions, and 20 % had at least one induced abortion. Fourteen patients that did not have signs of rupture were treated with expectant management while 13 patients were treated medically single dose methotrexate treatment had a success rate of 77%. One (7,6%) of the patients treated with methotrexate underwent surgery after the failure of two doses. Conclusion: Methotrexate may be the first line treatment in hemodynamically stable patients with no signs of rupture. But the patients should be informed about the fact that repeated doses or even surgery may be required

References

  • Atasü T, Sahmay S. Jinekoloji, 2. Baski, Nobel yayinevi, 547-557,2001.
  • Kirk E, Condous G, Bourne T: Ectopic pregnancy deaths: what should we be doing? Hosp Med. 65:657–660,2004.
  • Stovall TG, Ling FW: Single dose methotrexate: an exp anded clinical trial. Am J Obstet Gynecol. 168:1759– 1765,1993.
  • Kirk E, Condous G, Bourne T: The nonsurgical management of ectopic pregnancy. Ultrasound Obstet Gynecol. 27:91– 100,2006.
  • Coste J, Job-Spira N, Aublet-Cuvelier B, Germain E, Glowaczower E, Fernandez H, Pouly JL: Incidence of ectopic pregnancy. First results of a population-based register in France. Hum Reprod. 9:742-745,1994.
  • Elson J, Tailor A, Banerjee S, Salim R, Hillaby K, Jurkovic D: Expectant management of tubal ectopic pregnancy: prediction of successful outcome using decision tree analysis. Ultrasound Obstet Gynecol. 23:552–556,2004.
  • Korhonen J, Stenman UH, Ylostalo P: Serum human chorionic gonadotrophin dynamics during spontaneous resolution of ectopic pregnancy. Fertil Steril. 61:632–636,1994.
  • Trio D, Strobelt N, Picciolo C, Lapinski RH, Ghidini A: Prognostic factors for successful expectant management of ectopic pregnancy. Fertil Steril. 63:469–472,1995.
  • Atri M, Chow CM, Kintzen G, Gillett P, Aldis AA, Thibodeau M, Reinhold C, Bret PM: Expectant treatment of ectopic pregnancies: clinical and sonographic predictors. Am J Roentgenol. 176:123–127,2001.
  • Srivichai K, Uttavichai C, Tongsong T: Medical treatment of ectopic pregnancy: a ten-year review of 106 cases at Maharaj Nakorn Chiang Mai Hospital. J Med Assoc Thai. 89:1567-1571,2006.
  • Stika CS, Anderson L, Frederiksen MC: Single- dose methotrexate for the treatment of ectopic pregnancy: Northwestern Memorial Hospital three-year experience. Am J Obstet Gynecol. 174:1840-1846,1996.
  • Erdem M, Erdem A, Arslan M, Oc A, Biberoglu K, Gursoy R: Single -dose methotrexate for the treatment of unruptured ectopic pregnancy. Arch Gynecol Obstet. 270:201-204,2004.
  • Lispcomb GH, Givens VA, Meyer NL, Bran D: Previous ectopic pregnancy as a predictor of failure of systemic methotrexate therapy. Fertil Steril. 81:1221– 1224,2004.

Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi

Year 2007, Volume: 9 Issue: 1, 4 - 7, 01.03.2007

Abstract

Amaç: Klinigimizde ektopik gebelik tanisiyla tedavi ettigimiz olgularda tedavi yaklasimlarimizin degerlendirilmesidir. Yöntem: Ocak 2002-Aralik 2006 tarihleri arasinda ektopik gebelik nedeniyle tedavi edilen 60 olgu demografik özellikleri ve tedavi yaklasimlarimiz açisindan retrospektif olarak degerlendirildi. Bulgular: Hastalardan % 41,7’sinde bir ya da fazla spontan düsük, % 20’sinde en az bir kez yasal tahliye öyküsü mevcuttu. Rüptür bulgulari olmayan 14 hasta sadece izlenirken 13 hastaya medikal tedavi uygulandi. Tek doz metotreksat tedavisinin basari orani % 77 bulundu. Metotreksat tedavisi alan bir hastaya (% 7,6) ikinci dozla da basarili elde edilemeyince cerrahi yapildi. Sonuç: Rüptür bulgulari olmayan, genel durumu stabil hastalarda metotreksat tedavisi ilk seçenek olarak önerilebilir. Ancak hastalar tedavinin uzayabilecegi ve sonrasinda cerrahi de gerekebilecegi konusunda önceden bilgilendirilmelidir

References

  • Atasü T, Sahmay S. Jinekoloji, 2. Baski, Nobel yayinevi, 547-557,2001.
  • Kirk E, Condous G, Bourne T: Ectopic pregnancy deaths: what should we be doing? Hosp Med. 65:657–660,2004.
  • Stovall TG, Ling FW: Single dose methotrexate: an exp anded clinical trial. Am J Obstet Gynecol. 168:1759– 1765,1993.
  • Kirk E, Condous G, Bourne T: The nonsurgical management of ectopic pregnancy. Ultrasound Obstet Gynecol. 27:91– 100,2006.
  • Coste J, Job-Spira N, Aublet-Cuvelier B, Germain E, Glowaczower E, Fernandez H, Pouly JL: Incidence of ectopic pregnancy. First results of a population-based register in France. Hum Reprod. 9:742-745,1994.
  • Elson J, Tailor A, Banerjee S, Salim R, Hillaby K, Jurkovic D: Expectant management of tubal ectopic pregnancy: prediction of successful outcome using decision tree analysis. Ultrasound Obstet Gynecol. 23:552–556,2004.
  • Korhonen J, Stenman UH, Ylostalo P: Serum human chorionic gonadotrophin dynamics during spontaneous resolution of ectopic pregnancy. Fertil Steril. 61:632–636,1994.
  • Trio D, Strobelt N, Picciolo C, Lapinski RH, Ghidini A: Prognostic factors for successful expectant management of ectopic pregnancy. Fertil Steril. 63:469–472,1995.
  • Atri M, Chow CM, Kintzen G, Gillett P, Aldis AA, Thibodeau M, Reinhold C, Bret PM: Expectant treatment of ectopic pregnancies: clinical and sonographic predictors. Am J Roentgenol. 176:123–127,2001.
  • Srivichai K, Uttavichai C, Tongsong T: Medical treatment of ectopic pregnancy: a ten-year review of 106 cases at Maharaj Nakorn Chiang Mai Hospital. J Med Assoc Thai. 89:1567-1571,2006.
  • Stika CS, Anderson L, Frederiksen MC: Single- dose methotrexate for the treatment of ectopic pregnancy: Northwestern Memorial Hospital three-year experience. Am J Obstet Gynecol. 174:1840-1846,1996.
  • Erdem M, Erdem A, Arslan M, Oc A, Biberoglu K, Gursoy R: Single -dose methotrexate for the treatment of unruptured ectopic pregnancy. Arch Gynecol Obstet. 270:201-204,2004.
  • Lispcomb GH, Givens VA, Meyer NL, Bran D: Previous ectopic pregnancy as a predictor of failure of systemic methotrexate therapy. Fertil Steril. 81:1221– 1224,2004.
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Asli Somunkıran This is me

Aziz Rodan Sarohan This is me

Fuat Demırcı This is me

Oguz Yücel This is me

Publication Date March 1, 2007
Published in Issue Year 2007 Volume: 9 Issue: 1

Cite

APA Somunkıran, A., Sarohan, A. R., Demırcı, F., Yücel, O. (2007). Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi. Duzce Medical Journal, 9(1), 4-7.
AMA Somunkıran A, Sarohan AR, Demırcı F, Yücel O. Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi. Duzce Med J. March 2007;9(1):4-7.
Chicago Somunkıran, Asli, Aziz Rodan Sarohan, Fuat Demırcı, and Oguz Yücel. “Ektopik Gebelik Nedeniyle Tedavi Edilen 60 Olgunun Retrospektif Analizi”. Duzce Medical Journal 9, no. 1 (March 2007): 4-7.
EndNote Somunkıran A, Sarohan AR, Demırcı F, Yücel O (March 1, 2007) Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi. Duzce Medical Journal 9 1 4–7.
IEEE A. Somunkıran, A. R. Sarohan, F. Demırcı, and O. Yücel, “Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi”, Duzce Med J, vol. 9, no. 1, pp. 4–7, 2007.
ISNAD Somunkıran, Asli et al. “Ektopik Gebelik Nedeniyle Tedavi Edilen 60 Olgunun Retrospektif Analizi”. Duzce Medical Journal 9/1 (March 2007), 4-7.
JAMA Somunkıran A, Sarohan AR, Demırcı F, Yücel O. Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi. Duzce Med J. 2007;9:4–7.
MLA Somunkıran, Asli et al. “Ektopik Gebelik Nedeniyle Tedavi Edilen 60 Olgunun Retrospektif Analizi”. Duzce Medical Journal, vol. 9, no. 1, 2007, pp. 4-7.
Vancouver Somunkıran A, Sarohan AR, Demırcı F, Yücel O. Ektopik gebelik nedeniyle tedavi edilen 60 olgunun retrospektif analizi. Duzce Med J. 2007;9(1):4-7.