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Intramuscular Myxoma Of Deltoid Muscle

Year 2007, Volume: 9 Issue: 2, 4 - 7, 01.07.2007

Abstract

Myxomas are most commonly seen in heart. However, it may occur less frequently in other tissues such as subcutaneous and aponeurotic tissues, bone, genitourinary tract and skin. Extracardiac myxomas such as intramuscular myxomas are very rare. A 59 year old female patient complained of swelling and pain in the right upper extremity was admitted. On physical examination a palpable, soft mass was detected in the right deltoid muscle. On magnetic resonance angiography a hyper-intense, nodular, well circumscribed mass with hypointense septa was detected. The lesion was removed completely. On gross examination the specimen was measured 5.5x4x3 cm with surrounding striated muscle tissue. On cut section of the specimen a well circumscribed, gelatinous, glittering, white colored mass measuring 3.2x3x2.5 cm was found. On histological examination, the tumor was composed of small cells with scant cytoplasm and hyperchromatic, pycnotic nuclei and small number of histiocytic cells within wide myxoid areas. In this report a rare case of intramuscular myxoma which should be differentiated from many benign and malignant myxoid neoplasms of soft tissues was presented and discussed in clinical, radiological and pathological aspects

References

  • Stout A: Myxoma: The tumor of primitive mesenchyme. Ann Surg. 127: 706-719, 1948.
  • Weiss SW, Goldblum JR. Enzinger Weiss’s soft tissue tumors. 4. ed.: Intramuscular myxoma. St Louis. Mosby Inc. pp: 1425-1436, 2001.
  • Nielson GP, O’Connell JX, Rosenberg AE: Intramuscular myxoma. A Clinicopathologic Study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol. 22: 1222-1227, 1998.
  • van Roggen JFG, Mc Menamin ME, Fletcher CDM: Cellular myxoma of soft tissue: a clinicopathologic study of 38 cases confirming indolent clinical behaviour. Histopathol. 39: 287-297, 2001.
  • Kabukçuoglu F, Kabukçuoglu Y, Yilmaz B, Erdem B, Evren I: Mazabraud’s syndrome: Intramuscular myxoma associated with fibrous displasia. Pathol Oncol Res. 10: 121-123, 2004.
  • Murphey MD, McRae GA, Fanburg-Smith JC, Temple HT, Levine AM, Aboulafia AJ: Imaging of soft tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 225: 215-224, 2002.
  • Luna A, Martinez S, Bossen E: Magnetic resonance imaging of intramuscular myxoma with histological comparison and a review of the literature. Skeletal Radiol. 34: 19-28, 2005.
  • Hollowa P, Ka E, Leader M: Myxoid tumors: A guide to the morphological and immunohistochemical assessment of soft tissue myxoid lesions encountered in general surgical pathology. Curr Diagn Pathol. 11: 411-425, 2005.

Deltoid Kasin Intramusküler Miksomasi

Year 2007, Volume: 9 Issue: 2, 4 - 7, 01.07.2007

Abstract

Miksomalar en sik kalpte izlenir ancak, daha az oranda ciltalti, aponörotik doku, kemik, genitoüriner sistem ve deri gibi diger dokularda da görülebilir. Kalp disi yumusak dokulardan kökenli miksomalardan olan “çizgili kaslarin miksomasi” görece enderdir. Olgumuz, sag üst kolda zamanla olusan sislik ve hareket kisitliligi yakinmasiyla basvuran 59 yasinda kadin hastadir. Fizik muayenesinde deltoid kas bölgesinde siskinlik ve palpasyonda ele gelen yumusak kitle izlenmistir. Magnetik rezonans anjiografisinde deltoid kas içinde hiperintens, düzgün sinirli; içerisinde hipointens septalarin izlendigi kitle saptanmistir. Makroskopik incelemesinde, 5.5x4x3 cm ölçülerinde, çevresinde kirmizi kas seçilebilen yumusak doku parçasina kesit yapildiginda çevre kas dokusundan düzgün sinirla ayrilan 3.2x3x2.5 cm boyutlarda parlak beyaz renkte, jelatinöz alanlar içeren lezyon izlenmistir. Mikroskopik incelemede, tümörün genis mukoid alanlar içinde dar sitoplazmali, hiperkromatik piknotik görünümlü çekirdekleri bulunan hücreler ve az sayida histiyositi animsatan hücrelerden olustugu gözlenmistir. Ender olarak görülen, pek çok benign ve malign miksoid neoplazmdan histopatolojik olarak ayirt edilmesi bazen çok güç olabilen, yumusak dokunun ilginç benign tümörlerinden biri olan intramusküler miksoma olgusuna ait klinik, radyolojik, patolojik özellikler sunulmus ve literatür esliginde tartisilmistir

References

  • Stout A: Myxoma: The tumor of primitive mesenchyme. Ann Surg. 127: 706-719, 1948.
  • Weiss SW, Goldblum JR. Enzinger Weiss’s soft tissue tumors. 4. ed.: Intramuscular myxoma. St Louis. Mosby Inc. pp: 1425-1436, 2001.
  • Nielson GP, O’Connell JX, Rosenberg AE: Intramuscular myxoma. A Clinicopathologic Study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol. 22: 1222-1227, 1998.
  • van Roggen JFG, Mc Menamin ME, Fletcher CDM: Cellular myxoma of soft tissue: a clinicopathologic study of 38 cases confirming indolent clinical behaviour. Histopathol. 39: 287-297, 2001.
  • Kabukçuoglu F, Kabukçuoglu Y, Yilmaz B, Erdem B, Evren I: Mazabraud’s syndrome: Intramuscular myxoma associated with fibrous displasia. Pathol Oncol Res. 10: 121-123, 2004.
  • Murphey MD, McRae GA, Fanburg-Smith JC, Temple HT, Levine AM, Aboulafia AJ: Imaging of soft tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 225: 215-224, 2002.
  • Luna A, Martinez S, Bossen E: Magnetic resonance imaging of intramuscular myxoma with histological comparison and a review of the literature. Skeletal Radiol. 34: 19-28, 2005.
  • Hollowa P, Ka E, Leader M: Myxoid tumors: A guide to the morphological and immunohistochemical assessment of soft tissue myxoid lesions encountered in general surgical pathology. Curr Diagn Pathol. 11: 411-425, 2005.
There are 8 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

İsin Dogan Ekıcı This is me

Ferda Özkan This is me

Nil Çomunoglu This is me

Halil İbrahim Bekler This is me

Fatih Parmaksızoglu This is me

Neslihan Kabakçı This is me

Sedat Çöloglu This is me

Selçuk Bılgı This is me

Publication Date July 1, 2007
Published in Issue Year 2007 Volume: 9 Issue: 2

Cite

APA Ekıcı, İ. D., Özkan, F., Çomunoglu, N., Bekler, H. İ., et al. (2007). Deltoid Kasin Intramusküler Miksomasi. Duzce Medical Journal, 9(2), 4-7.
AMA Ekıcı İD, Özkan F, Çomunoglu N, Bekler Hİ, Parmaksızoglu F, Kabakçı N, Çöloglu S, Bılgı S. Deltoid Kasin Intramusküler Miksomasi. Duzce Med J. July 2007;9(2):4-7.
Chicago Ekıcı, İsin Dogan, Ferda Özkan, Nil Çomunoglu, Halil İbrahim Bekler, Fatih Parmaksızoglu, Neslihan Kabakçı, Sedat Çöloglu, and Selçuk Bılgı. “Deltoid Kasin Intramusküler Miksomasi”. Duzce Medical Journal 9, no. 2 (July 2007): 4-7.
EndNote Ekıcı İD, Özkan F, Çomunoglu N, Bekler Hİ, Parmaksızoglu F, Kabakçı N, Çöloglu S, Bılgı S (July 1, 2007) Deltoid Kasin Intramusküler Miksomasi. Duzce Medical Journal 9 2 4–7.
IEEE İ. D. Ekıcı, F. Özkan, N. Çomunoglu, H. İ. Bekler, F. Parmaksızoglu, N. Kabakçı, S. Çöloglu, and S. Bılgı, “Deltoid Kasin Intramusküler Miksomasi”, Duzce Med J, vol. 9, no. 2, pp. 4–7, 2007.
ISNAD Ekıcı, İsin Dogan et al. “Deltoid Kasin Intramusküler Miksomasi”. Duzce Medical Journal 9/2 (July 2007), 4-7.
JAMA Ekıcı İD, Özkan F, Çomunoglu N, Bekler Hİ, Parmaksızoglu F, Kabakçı N, Çöloglu S, Bılgı S. Deltoid Kasin Intramusküler Miksomasi. Duzce Med J. 2007;9:4–7.
MLA Ekıcı, İsin Dogan et al. “Deltoid Kasin Intramusküler Miksomasi”. Duzce Medical Journal, vol. 9, no. 2, 2007, pp. 4-7.
Vancouver Ekıcı İD, Özkan F, Çomunoglu N, Bekler Hİ, Parmaksızoglu F, Kabakçı N, Çöloglu S, Bılgı S. Deltoid Kasin Intramusküler Miksomasi. Duzce Med J. 2007;9(2):4-7.