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Fibrous hamartoma of infancy: An immunohistopatologyc study

Year 2007, Volume: 9 Issue: 2, 34 - 36, 01.07.2007

Abstract

Fibrous hamartoma of infancy (FHI) is an uncommon lesion, occurring as a superficial mass. We present one case of fibrous hamartoma in the ingunal region. The clinical and histopathologic features, and treatment results of child with (FHI) were described and the literature was reviewed. Criteria for histologic diagnosis include the presence of fasicles of myof ibroblasts, disorganized mature adipocytes and small rounded primitive mesenchymal cells. Immunohistochemically, muscle specific actin and vimentin were expressed in the myofibroblastic component, and vimentin was only expressed in the primitive component. The treatment of this uncommonly seen pathology is completely excision

References

  • Reye RD: A consideration of certain subdermal fibromatous tumors of infancy. J Pathol Bacteriol. 72:149-54, 1956.
  • Enzinger FM: Fibrous hamartoma of infancy. Cancer. 18:241-8,1965.
  • Carretto E, Dall'Igna P, Alaggio R, Siracusa F, Granata C, Ferrari A, Cecchetto G: a Fibrous hamartoma of infancy: An Italian multi-institutional experience. J Am Acad Dermatol. 54:800- 3, 2006.
  • Dickey GE, Sotelo-Avila C: Fibrous hamartoma of infancy: current review. Pediatr Dev Pathol. 2:236-43,1999.
  • Fletcher CDM, Powell G, Van Noorden S, McKee PH: Fibrous hamartoma of infancy: a histochemical and immuno- histochemical study. Histopathology. 12:65-74,1988.
  • Goldstein SA, Imbriglia JE: Fibrous hamartoma of the wrist in infancy. J Hand Surg. 11:847-9, 1986.
  • Enzinger FM, Weiss SW: Fibrous tumors of infancy and childhood. In: Soft tissue tumors. St Louis. Mosby. pp: 231-33, 1995.
  • Sotelo-Avila C, Bale PM: Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis. Pediatr Pathol. 14:39-52, 1994.
  • Cooper PH: Fibrous hamartoma of infancy and childhood. J Cutan Pathol. 19:257-67, 1992.
  • Thami GP, Jaswal R, Kanwar AJ: Fibrous hamartoma of infancy in the scrotum. Pediatr Dermatol. 15:326, 1998.
  • Paller AS, Gonzalez-Crussi F, Sherman JO: Fibrous hamartoma of infancy. Eight additional cases and a review of the literature. Arch Dermatol. 125:88-91, 1989. Heenan PJ: Tumors of the fibrous tissue involving the skin. In Elder D, Elenitsas R, Jaworsky C, Johnson B, (eds): Lever’s histopathology of the skin. 8th ed. Philadelphia. Lippincott-Raven. pp: 878- 80, 1997. Taskin E, Kiliç M, Özercan IH, Yilmaz E, Varol I, Aygün AD: Infantil fibröz hamartom. Bir vaka takdimi. Çocuk Sagligi ve Hastaliklari Dergisi. 47, 277- 279, 2004.
  • Ashwood N, Witt JD, Hall-Craggs MA: Fibrous hamartoma of infancy at the wrist and the use of MRI in preoperative planning. Pediatr Radiol. 31: 450-2, 2001.
  • Dickey GE and Cirilo Sotelo-Avila: Fibrous Hamartoma of Infancy: Current Review. Pediatric and Developmental Pathology. 2:236-43, 1999.
  • Popek EJ, Montgomery EA, Fourcroy JL: Fibrous hamartoma of infancy in the genital region: findings in 15 cases. J Urol. 152:990-3,1994.

Infantil fibröz hamartom: Immunohistopatolojik bir çalisma

Year 2007, Volume: 9 Issue: 2, 34 - 36, 01.07.2007

Abstract

Infantil fibröz hamartom (IFH) yüzeyel bir kitle olarak olusan nadir bir lezyondur. Burada inguinal bölgede fibröz hamartomlu bir olgu sunuldu. IFH’li çocugun klinik ve histopatolojik özellikleri ve tedavi sonuçlari tanimlandi ve literatürle degerlendirildi. Histopatolojik özellikleri miyofibroblast demetlerinin varligi, disorganize matür adipozitler ve küçük yuvarlak yassi primitif mezenkimal hücrelerin varligini içerdi. Immunohistokimyasal olarak miyofibroblastik komponent aktin ile vimentin, primitif komponentin ise sadece vimentin içermekteydi. Çocuklarda nadir olarak görülen bu patolojinin tedavisi komplet eksizyondur

References

  • Reye RD: A consideration of certain subdermal fibromatous tumors of infancy. J Pathol Bacteriol. 72:149-54, 1956.
  • Enzinger FM: Fibrous hamartoma of infancy. Cancer. 18:241-8,1965.
  • Carretto E, Dall'Igna P, Alaggio R, Siracusa F, Granata C, Ferrari A, Cecchetto G: a Fibrous hamartoma of infancy: An Italian multi-institutional experience. J Am Acad Dermatol. 54:800- 3, 2006.
  • Dickey GE, Sotelo-Avila C: Fibrous hamartoma of infancy: current review. Pediatr Dev Pathol. 2:236-43,1999.
  • Fletcher CDM, Powell G, Van Noorden S, McKee PH: Fibrous hamartoma of infancy: a histochemical and immuno- histochemical study. Histopathology. 12:65-74,1988.
  • Goldstein SA, Imbriglia JE: Fibrous hamartoma of the wrist in infancy. J Hand Surg. 11:847-9, 1986.
  • Enzinger FM, Weiss SW: Fibrous tumors of infancy and childhood. In: Soft tissue tumors. St Louis. Mosby. pp: 231-33, 1995.
  • Sotelo-Avila C, Bale PM: Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis. Pediatr Pathol. 14:39-52, 1994.
  • Cooper PH: Fibrous hamartoma of infancy and childhood. J Cutan Pathol. 19:257-67, 1992.
  • Thami GP, Jaswal R, Kanwar AJ: Fibrous hamartoma of infancy in the scrotum. Pediatr Dermatol. 15:326, 1998.
  • Paller AS, Gonzalez-Crussi F, Sherman JO: Fibrous hamartoma of infancy. Eight additional cases and a review of the literature. Arch Dermatol. 125:88-91, 1989. Heenan PJ: Tumors of the fibrous tissue involving the skin. In Elder D, Elenitsas R, Jaworsky C, Johnson B, (eds): Lever’s histopathology of the skin. 8th ed. Philadelphia. Lippincott-Raven. pp: 878- 80, 1997. Taskin E, Kiliç M, Özercan IH, Yilmaz E, Varol I, Aygün AD: Infantil fibröz hamartom. Bir vaka takdimi. Çocuk Sagligi ve Hastaliklari Dergisi. 47, 277- 279, 2004.
  • Ashwood N, Witt JD, Hall-Craggs MA: Fibrous hamartoma of infancy at the wrist and the use of MRI in preoperative planning. Pediatr Radiol. 31: 450-2, 2001.
  • Dickey GE and Cirilo Sotelo-Avila: Fibrous Hamartoma of Infancy: Current Review. Pediatric and Developmental Pathology. 2:236-43, 1999.
  • Popek EJ, Montgomery EA, Fourcroy JL: Fibrous hamartoma of infancy in the genital region: findings in 15 cases. J Urol. 152:990-3,1994.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Hayrettin Öztürk This is me

Kazim Karaarslan This is me

Fahri Yılmaz This is me

Hülya Öztürk This is me

Publication Date July 1, 2007
Published in Issue Year 2007 Volume: 9 Issue: 2

Cite

APA Öztürk, H., Karaarslan, K., Yılmaz, F., Öztürk, H. (2007). Infantil fibröz hamartom: Immunohistopatolojik bir çalisma. Duzce Medical Journal, 9(2), 34-36.
AMA Öztürk H, Karaarslan K, Yılmaz F, Öztürk H. Infantil fibröz hamartom: Immunohistopatolojik bir çalisma. Duzce Med J. July 2007;9(2):34-36.
Chicago Öztürk, Hayrettin, Kazim Karaarslan, Fahri Yılmaz, and Hülya Öztürk. “Infantil fibröz Hamartom: Immunohistopatolojik Bir çalisma”. Duzce Medical Journal 9, no. 2 (July 2007): 34-36.
EndNote Öztürk H, Karaarslan K, Yılmaz F, Öztürk H (July 1, 2007) Infantil fibröz hamartom: Immunohistopatolojik bir çalisma. Duzce Medical Journal 9 2 34–36.
IEEE H. Öztürk, K. Karaarslan, F. Yılmaz, and H. Öztürk, “Infantil fibröz hamartom: Immunohistopatolojik bir çalisma”, Duzce Med J, vol. 9, no. 2, pp. 34–36, 2007.
ISNAD Öztürk, Hayrettin et al. “Infantil fibröz Hamartom: Immunohistopatolojik Bir çalisma”. Duzce Medical Journal 9/2 (July 2007), 34-36.
JAMA Öztürk H, Karaarslan K, Yılmaz F, Öztürk H. Infantil fibröz hamartom: Immunohistopatolojik bir çalisma. Duzce Med J. 2007;9:34–36.
MLA Öztürk, Hayrettin et al. “Infantil fibröz Hamartom: Immunohistopatolojik Bir çalisma”. Duzce Medical Journal, vol. 9, no. 2, 2007, pp. 34-36.
Vancouver Öztürk H, Karaarslan K, Yılmaz F, Öztürk H. Infantil fibröz hamartom: Immunohistopatolojik bir çalisma. Duzce Med J. 2007;9(2):34-6.