Treatment of Refractory Generalized Status Epilepticus with Propofol (Case Report)

Year 2008, Volume: 10 Issue: 3, 53 - 56, 01.12.2008

Kazım Karaaslan Esra Gümüş Nebahat Gülcü Burcu Altunrende

Abstract

Status epilepticus, a major medical emergency associated with significant morbidity and mortality, is defined as a continuous, generalized, convulsive seizure lasting more than 5 minutes, or two or more seizures during which the patient does not return to baseline consciousness. Refractory status epilepticus is defined as seizures lasting more than 2 hours, or seizures recurring at a rate of two or more episodes per hour without recovery to baseline between seizures, despite treatment with conventional antiepileptic drugs. A case of refractory status epilepticus controlled by propofol infusion is presented in this report, and discussed in the light of literature

Keywords

Refractory status epilepticus, Propofol

Dirençli Jeneralize Status Epileptikusun Propofol ile Tedavisi (Olgu Sunumu)

Abstract

Status epileptikus, jeneralize, konvülzif nöbetlerin sürekli olarak 5 dakika veya daha uzun sürmesi ya da bilinçte düzelme olmaksızın 2 veya daha fazla sayıda nöbet geçirilmesi şeklinde tanımlanmaktadır. Morbidite ve mortalitesi yüksek acil tıbbi durumlardan biridir. Dirençli status epileptikus ise konvansiyonel antiepileptik ilaç tedavisine rağmen, iki saatten fazla süren nöbetlerin olması veya saatte iki veya daha fazla nöbetin olduğu ve nöbet aralarında bilincin bazal değerlere dönmediği tablo olarak tanımlanmaktadır. Bu makalede propofol infüzyonu ile kontrol altına alınabilen dirençli bir status epileptikus olgusu sunulmuş ve literatür eşliğinde tartışılmıştır

Keywords

Dirençli status epileptikus, Propofol

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