Cerebral Venous Thrombosis: Analysis of Sixteen Cases

Year 2009, Volume: 11 Issue: 1, 32 - 37, 01.03.2009

Mehmet Güney Şenol Erdem Toğrol Tayfun Kaşıkçı Hakan Tekeli Fatih Özdağ Mehmet Saraçoğlu

Abstract

Aim: Cerebral Venous Thrombosis occurs less frequently in comparison to the arterial diseases of the brain. The diagnosis can only be made through imaging techniques and its mortality and morbidity is relatively high. Material and Methods: The etiological, topographic and clinical features were reviewed in the 16 patients (7 female, 9 male) accepted to our hospital between 2004 and 2008 with a diagnosis of Cerebral Venous Thrombosis. Results: Fourteen of the patients complained from headache. Six patients had findings intracranial hypertension, 4 had focal neurological findings, 4 had seizures 2 of which were generalized status epilepticus, 2 had a history of craniocerebral trauma, on initial presentation 2 had confusion, 1 had sensory findings and 1 patient had fever and skin findings. Two patient presented in the postpartum period, 2 patients had a history of oral contraceptive use; 4 had a neighboring infectious area. Two had homocysteinemia and 1 patient had thrombositosis and 1 had Behcet disease. In five patients, one than one sinus was obstructed, in 2 of those venous infarcts was present. Fifteen patients eventually ended with no pathological finding. The most frequent etiological factor was infection and the most frequent finding was intracranial hypertension . Conclusion: In this study appropriate treatment options are emphasized. diagnosis of Cerebral Venous Thrombosis and the importance of

Keywords

cerebral venous thrombosis, MR venography, predisposing factor

Serebral Venöz Tromboz: 16 Olgunun İncelenmesi

Abstract

Giriş: Serebral Venöz Tromboz beynin arteryel hastalıklarına oranla nadir görülür, tanı ancak görüntüleme tetkikleriyle ortaya konabilir ve morbiditesi oldukça yüksektir. Gereç ve Yöntem: 2004–2008 yılları arasında kliniğimize yatırılan Serebral Venöz Tromboz tanısı almış 7’si kadın, 16 hastanın etyolojik, topografik ve klinik özellikleri değerlendirildi. Bulgular: Hastaların 14’u baş ağrısından yakınıyordu. Kafa içi basınç artısı bulguları 6, fokal nörolojik bulgu 4, ikisi jeneralize status epileptikus olmak üzere nöbet 4, kafa travması 2, konfüzyon 1, duysal belirtiler 1, ateş ve deri döküntüsü 1 hastada vardı. İki hasta postpartum dönemde hastalanmıştı, 3 hastada oral kontraseptif kullanımı, 4 hastada ise komşu bir enfeksiyöz odak vardı. Hastaların ikisinde ise homosisteinemi, birisinde trombositoz, birisinde Behçet hastalığı saptandı. Beş hastada birden çok sinuste tıkanma olduğu, bunların ikisinde venöz enfarkt geliştiği görüldü. Onbeş hasta klinikten patolojik bulgusu olmaksızın çıkarıldı. En sık intrakranial hipertansiyon bulguları, neden olarak da enfeksiyon nedenlerini gözlemledik. Tartışma: Bu çalışmada Serebral Venöz Tromboz’un tanısı, uygun tetkik ve tedavi seçeneklerinin önemi üzerinde duruldu

Keywords

serebral venöz tromboz, MR venografi, predispozan etmen

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