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Locked-In Syndrome: Three Cases Report

Year 2010, Volume: 12 Issue: 2, 54 - 57, 01.07.2010

Abstract

Locked-in syndrome is rare. The clinical criteria of complete locked-in syndrome are tetraplegiaand paralysis of cranial nerves except vertical eye movements and preserved consciousness.The most common lesion underlying the locked-in syndrome is a thrombosis of the basilar arteryand as well as an almost total pontine infarction was demonstrated on CT-and MRI-scans.Intravenous and intra arterial thrombolysis have been used successfully in a selective group ofpatients with ischemic stroke. Intensive and early rehabilitation improved the functional recoveryand reduced the mortality rate. Commonly leads to death, frequently due to pneumonia. In thisreport we present cases with locked-in syndrome that were followed up in our clinic

References

  • Kransnianski M, Gaul C, Neudecker S, Behrmann C, Schlüter A, Winterholler M: Yawning despite trismus in a patient with locked-in syndrome caused by a thrombosed megadolichobasilar artery. Clinical Neurology and Neurosurgery.106:44-46, 2003.
  • Gilroy J.( çeviri Karabudak R): Locked-in Sendromu. Temel nöroloji. 270, 2002
  • Mellado P, Sandoval P, Tevah J, Huete I, Castillo L: Intra- arterial thrombolysis in locked-in syndrome. Report of two cases:Rev Med Chil. 132 (3):357-60, 2004
  • Casanova E, Lazzari RE, Lotta S, Mazzucchi A: Locked-in syndrome:improvement in the prognosis after an early intensive multidisciplinary rehabilitation. Archives of physical medicine and rehabilitation. 84(6):862-867, 2003.
  • Ockey RR, Mowry D, Varghese G: Use of Sinemet in locked- in syndrome: a report of two cases. Arch Phys Med Rehabil. 76(9):868-70, 1995.
  • Ebinger G, Huyghens L, Corne L, Aelbrecht W: Reversible ‘’locked-in’’ syndromes. Intensive Care Med. 11(4):218-9, 1985.
  • Budak F, Ilhan A, Ozmenoglu M, Komsuoglu SS: Locked-in syndrome: a case report. Clin Electroencephalogr. 25(1):40-3, 1994.
  • Breen P, Hannon V: Locked-in syndrome: a catastrophic complication after surgery. Br J Anaesth. 92(2):286-8, 2004.
  • Patterson JR, Grabosis M: Locked-in syndrome: a review of 139 cases. Stroke. 17:758-764,2005.

Locked-In Sendromu: Üç Olgu Sunumu

Year 2010, Volume: 12 Issue: 2, 54 - 57, 01.07.2010

Abstract

Locked-in sendromu nadir görülmektedir. Komple formunun klinik kriterleri tetrapleji vebilincin korunduğu vertikal göz hareketleri dışındaki kranyal sinir paralizileridir. Locked-insendromunun altında yatan en sık lezyon baziler arterin trombozudur ve buna bağlı gelişen totalpontin infarkt tomografi ve manyetik rezonans görüntüleme ile gösterilmiştir. İntravenöz veintra-arterial trombolizis iskemik stroklu seçilmiş grup hastalarda başarıyla kullanılmıştır. Yoğunve erken rehabilitasyon fonksiyonel iyileşmeyi artırır ve mortalite oranını düşürür. En sık ölümnedeni pnömonidir. Burada kliniğimizde takip ettiğimiz locked-in sendromlu üç hastayı sunduk

References

  • Kransnianski M, Gaul C, Neudecker S, Behrmann C, Schlüter A, Winterholler M: Yawning despite trismus in a patient with locked-in syndrome caused by a thrombosed megadolichobasilar artery. Clinical Neurology and Neurosurgery.106:44-46, 2003.
  • Gilroy J.( çeviri Karabudak R): Locked-in Sendromu. Temel nöroloji. 270, 2002
  • Mellado P, Sandoval P, Tevah J, Huete I, Castillo L: Intra- arterial thrombolysis in locked-in syndrome. Report of two cases:Rev Med Chil. 132 (3):357-60, 2004
  • Casanova E, Lazzari RE, Lotta S, Mazzucchi A: Locked-in syndrome:improvement in the prognosis after an early intensive multidisciplinary rehabilitation. Archives of physical medicine and rehabilitation. 84(6):862-867, 2003.
  • Ockey RR, Mowry D, Varghese G: Use of Sinemet in locked- in syndrome: a report of two cases. Arch Phys Med Rehabil. 76(9):868-70, 1995.
  • Ebinger G, Huyghens L, Corne L, Aelbrecht W: Reversible ‘’locked-in’’ syndromes. Intensive Care Med. 11(4):218-9, 1985.
  • Budak F, Ilhan A, Ozmenoglu M, Komsuoglu SS: Locked-in syndrome: a case report. Clin Electroencephalogr. 25(1):40-3, 1994.
  • Breen P, Hannon V: Locked-in syndrome: a catastrophic complication after surgery. Br J Anaesth. 92(2):286-8, 2004.
  • Patterson JR, Grabosis M: Locked-in syndrome: a review of 139 cases. Stroke. 17:758-764,2005.
There are 9 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Ertuğrul Uzar This is me

Mustafa Yılmaz This is me

Hasan Rıfat Koyuncuoğlu This is me

Serkan Kılbaş This is me

Publication Date July 1, 2010
Published in Issue Year 2010 Volume: 12 Issue: 2

Cite

APA Uzar, E., Yılmaz, M., Koyuncuoğlu, H. R., Kılbaş, S. (2010). Locked-In Sendromu: Üç Olgu Sunumu. Duzce Medical Journal, 12(2), 54-57.
AMA Uzar E, Yılmaz M, Koyuncuoğlu HR, Kılbaş S. Locked-In Sendromu: Üç Olgu Sunumu. Duzce Med J. July 2010;12(2):54-57.
Chicago Uzar, Ertuğrul, Mustafa Yılmaz, Hasan Rıfat Koyuncuoğlu, and Serkan Kılbaş. “Locked-In Sendromu: Üç Olgu Sunumu”. Duzce Medical Journal 12, no. 2 (July 2010): 54-57.
EndNote Uzar E, Yılmaz M, Koyuncuoğlu HR, Kılbaş S (July 1, 2010) Locked-In Sendromu: Üç Olgu Sunumu. Duzce Medical Journal 12 2 54–57.
IEEE E. Uzar, M. Yılmaz, H. R. Koyuncuoğlu, and S. Kılbaş, “Locked-In Sendromu: Üç Olgu Sunumu”, Duzce Med J, vol. 12, no. 2, pp. 54–57, 2010.
ISNAD Uzar, Ertuğrul et al. “Locked-In Sendromu: Üç Olgu Sunumu”. Duzce Medical Journal 12/2 (July 2010), 54-57.
JAMA Uzar E, Yılmaz M, Koyuncuoğlu HR, Kılbaş S. Locked-In Sendromu: Üç Olgu Sunumu. Duzce Med J. 2010;12:54–57.
MLA Uzar, Ertuğrul et al. “Locked-In Sendromu: Üç Olgu Sunumu”. Duzce Medical Journal, vol. 12, no. 2, 2010, pp. 54-57.
Vancouver Uzar E, Yılmaz M, Koyuncuoğlu HR, Kılbaş S. Locked-In Sendromu: Üç Olgu Sunumu. Duzce Med J. 2010;12(2):54-7.