Effects Of Oral Carbamazepine With 2% Lidocaine On Maxillary And Mandibular Nerve Blocks In Trigeminal Neuralgia

Year 2010, Volume: 12 Issue: 3, 19 - 23, 01.12.2010

Metin Kaplan Mehmet Baykal

Abstract

Purpose: We evaluated the therapeutic efficacy of associating the oral administration ofcarbamazepine with 2% lidocaine for maxillary and mandibular nerve blocks in acute and longterm pain relief of trigeminal neuralgia in this retrospective study.Methods: A total of 13 patients (9 men and 4 women), with trigeminal neuralgia aged between34 and 91 years (Mean age 53±13.39), and who applied to our hospitals Pain Unit between July2007-July 2009 were included in this study. The records of 13 patients suffering pain due totrigeminal neuralgia were examined; pain free periods, treatment success, side effects, andrecurrence were recorded.Results: At the end of a 5-week treatment period, pain relapses ceased in all patients. Themajority of patients benefited remarkably from the treatment after week three. Pain recurred inone patient after one month and in two patients after six months. No relapse was observed inthe other 10 patients during the 12-month follow-up period. Conclusion: Pain episodes in trigeminal neuralgia cases may be controlled by maxillary andmandibular blocks applied with oral carbamazepine and 2% lidocaine. Favorable results areobtained in both the short and long–term, and notable increases are observed in the comfort andquality of life of patients

Keywords

Trigeminal neuralgia, Carbamazepine, Lidocaine, Analgesic Block

Trigeminal Nevraljide Oral Karbamazepin ile Birlikte %2 Lidokain ile Uygulanan Maksiler ve Mandibuler Sinir Bloklarının Etkileri

Abstract

Amaç: Bu retrospektif çalışmada oral karbamazepin ile birlikte % 2 lidokain kullanılarakmaksiler ve mandibuler sinir bloğu uygulamasının akut ve uzun dönemde trigeminal nevraljiağrısı tedavisindeki etkilerinin araştırılması amaçlanmıştır.Yöntem: Trigeminal nevralji nedeniyle ağrısı olan ve Temmuz 2007-Temmuz 2009 tarihleriarasında hastanemiz Ağrı Ünitesine başvuran yaşları 34 ve 91 (Ortalama yaş 53±13.39) arasındadeğişen toplam 13 olgunun (9 erkek ve 4 kadın) kayıtları ağrısız geçen dönemleri, tedavibaşarısı, yan etkiler ve hastalığın tekrarlaması yönünden incelendi.Bulgular: 5 haftalık tedavi periyodu sonunda tüm olgularda ağrı atakları geçmişti. Olgularınçoğu 3. haftadan itibaren tedaviden belirgin şekilde fayda gördüler. Bir olguda 1 ay sonra, ikiolguda 6 ay sonra ağrı atakları tekrar başladı. Diğer 10 olguda 12 aylık izlemede ağrı atağıoluşmadı.Sonuç: Trigeminal nevralji hastalarının ağrı atakları oral karbamazepin ve % 2 lidokain ileuygulanan maksiler ve mandibuler sinir blokları ile kontrol altına alınabilmektedir. Bu tedaviyöntemi ile kısa ve uzun dönemde başarılı sonuçlar alınabilmekte ve olguların konforu ve hayatkalitesi yönünden dikkat çekici artışlar gözlenmektedir

Keywords

Trigeminal nevralji, Karbamazepin, Lidokain, Analjezik sinir bloğu

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