Evaluation of the Relation Between Ovarian Reserve and Cyst Dimension in Patients with Endometrioma

Year 2011, Volume: 13 Issue: 3, 1 - 5, 01.12.2011

Ulku Bayar Mehmet Vural

Abstract

ObjectivesEndometriosis is a gynecologic disease which has high prevalence among infertile population.It has increasing importance particularly for the patients with determined endometrioma cystwhen there is an infertility problem during the surgery. In this study, we aimed to evaluate theovarian reserve with basal hormone values and clomiphene citrate challenge test in patients withendometrioma, to compare results with control group and to determine a possible relationshipbetween the cyst diameter and the ovarian reserve in condition of getting significant results.MethodsThirty-five patients who had diagnosis of endometrioma were included in the study. As thecontrol group, 35 patients with borderline male infertility and similar demographiccharacteristics were selected from Infertility Clinic of the same hospital.ResultsThere was no significant distinction between mean age values of groups. Mean cyst diameterwas 33.65 ± 17.08 mm in the endometrioma group. No significant difference was determinedbetween day 3 FSH, day 3 estradiol and day 10 FSH value after clomiphene citrate challengetest. There was also no significant distinction when the hormone values were categorized asnormal and abnormal.ConclusionAlthough being statistically insignificant, due to the detection of a borderline significance inthe 10th day FSH values after clomiphene citrate test and obtaining elevated hormone levels inthe endometrioma group, we can conclude that it is probable to obtain siginificant results in alarger population

Keywords

endometriosis, infertility, clomiphene citrate challenge test

Endometriomalı Hastalarda Kist Çapı ile Over Rezervi Arasındaki İlişkinin Değerlendirilmesi

Abstract

Amaç Endometriozis, infertil popülasyonda yüksek prevalansa sahip bir jinekolojik hastalıktır.Özellikle infertilite problemi olan hastalarda cerrahi esnasında endometrioma kisti karşımızaçıktığında daha da önem kazanmaktadır. Bu çalışmada, bazal hormon seviyeleri ve klomifensitrat testi ile endometrioma hastalarının over rezervini değerlendirmeyi, sonuçları kontrol grubuile karşılaştırmayı ve kist çapı ile over rezervi arasında muhtemel bir ilişkiyi anlamlılıkderecesinde araştırmayı planladık.Metod Endometrioma tanısı alan 35 hasta çalışmaya dahil edildi. Benzer demografik özelliklere sahipve sınırda erkek faktör infertilitesi olan 35 kontrol hastası aynı hastanenin İnfertilitePolikliniğinden seçildi.BulgularGrupların yaş ortalamaları arasında anlamlı bir fark yoktu. Endometrioma grubunda kistortalaması 33,65 ± 17,08 idi. Üçüncü gün FSH, estradiol ve klomifen sitrat sonrası 10.gün FSHdeğerlerinde anlamlı fark tespit edilmedi. Hormon değerleri normal ve anormal olaraksınıflandırıldığında da anlamlı fark tespit edilmedi.Sonuç İstatistiksel olarak anlamlılık tespit edilemese de; klomifen sitrat testi sonrasında 10. gün FSHdeğerinde sınırda bir anlamlılık tespit edilmesi ve kontrol grubuna nazaran endometriomagrubunda yüksek (anormal) hormon değerleri elde edilmesinden dolayı; büyük gruplarda dahaanlamlı sonuçlar elde edilebileceği yorumu yapılabilir

Keywords

endometriozis, infertilite, klomifen sitrat testi

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