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Pediatric Peptic Ulcer Disease: Is It Significant?

Year 2015, Volume: 17 Issue: 3, 133 - 135, 01.12.2015

Abstract

Peptic ulcer disease is extremely rare in pediatric age. However, it can cause severegastrointestinal bleeding. Pediatric peptic ulcers are usually associated with nonspecificsymptoms. Therefore, the most important factor for early diagnosis is clinical suspicion aboutthe presence of this disease. Upper gastrointestinal endoscopy is the gold standard method fordiagnosis. Medical management almost always provides high clinical success. Pediatriciansshould have sufficient background information about this disease and endoscopic investigationshould not be ignored when clinically indicated.Key Worlds: Peptic ulcer, childhood, H. pylori

References

  • Warren J, Marshall B. Unidentified curved bacillus on gastric epithelium in chronic active gastritis. Lancet 1983; I: 1273- 1275.
  • Pacifico L, Anania C, Osborn JF, Ferraro F, Chiesa C. Consequences of Helicobacter pylori infection in children. World J Gastroenterol. 2010 Nov 7;16(41):5181-5194.
  • Calvet X, Ramírez Lázaro MJ, Lehours P, Mégraud F. Diagnosis and epidemiology of Helicobacter pylori infection. Helicobacter. 2013;18 Suppl 1:5-11.
  • Sherman PM. Appropriate strategies for testing and treating Helicobacter pylori in children: when and how? Am J Med 2004; 117 Suppl 5A: 30S-35S.
  • Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002; 347: 1175-1186.
  • Kasırga E. Cocukluk Cağında Peptik Ulser Hastalığı. Turkiye Klinikleri J Pediatr Sci 2012; 8(1):11-16.
  • Macarthur C, Saunders N, Feldman W. Helicobacter pylori, gastroduodenal disease, and recurrent abdominal pain in children. JAMA 1995; 273: 729-734.
  • Roma E, Kafritsa Y, Panayiotou J, Liakou R, Constantopoulos A. Is peptic ulcer a common cause of upper gastrointestinal symptoms? Eur J Pediatr 2001; 160: 497-500.
  • Ecevıt ÇÖ, Özgenç F, Yüksekkaya HA, Ünal F, Arikan Ç, Yağci RV. Peptic ulcer disease in children: an uncommon disorder with subtle symptomatology. Turk J Gastroenterol. 2012;23(6):666-669.
  • Kato S, Nishino Y, Ozawa K, Konno M, Maisawa S, Toyoda S, Tajiri H, Ida S, Fujisawa T, Iinuma K. The prevalence of Helicobacter pylori in Japanese children with gastritis or peptic ulcer disease. J Gastroenterol 2004; 39: 734-738.
  • Kalach N, Bontems P, Koletzko S, Mourad-Baars P, Shcherbakov P, Celinska-Cedro D, Iwanczak B, Gottrand F, Martinez-Gomez MJ, Pehlivanoglu E, Oderda G, Urruzuno P, Casswall T, Lamireau T, Sykora J, Roma-Giannikou E, Veres G, Wewer V, Chong S, Charkaluk ML, Mégraud F, Cadranel S. Frequency and risk factors of gastric and duodenal ulcers or erosions in children: a prospective 1-month European multicenter study. Eur J Gastroenterol Hepatol. 2010 Oct;22(10):1174-1181.
  • Oderda G, Shcherbakov P, Bontems P, Urruzuno P, Romano C, Gottrand F, Gómez MJ, Ravelli A, Gandullia P, Roma E, Cadranel S, De Giacomo C, Canani RB, Rutigliano V, Pehlivanoglu E, Kalach N, Roggero P, Celinska-Cedro D, Drumm B, Casswall T, Ashorn M, Arvanitakis SN. Results from the pediatric European register for treatment of Helicobacter pylori (PERTH). Helicobacter 2007; 12: 150- 156
  • Tutar E, Ertem D, Kotiloglu Karaa E, Pehlivanoglu E. Endoscopic and histopathologic findings associated with H. pylori infection in very young children. Dig Dis Sci. 2009;54(1):111-117.
  • Yadav SK, Gupta V, El Kohly A, Al Fadhli W. Perforated duodenal ulcer: a rare complication of deferasirox in children. Indian J Pharmacol. 2013;45(3):293-294.
  • Cruze K, Snyder WH Jr. Acute perforation of the alimentary tract in infancy and childhood. Ann Surg. 1961;154:93-99.
  • Ford AC, Forman D, Hunt RH, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials. BMJ. 2014; 348:1-13.

PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?

Year 2015, Volume: 17 Issue: 3, 133 - 135, 01.12.2015

Abstract

Çocukluk çağı peptik ülserleri yetişkinlere göre oldukça nadir olmakla birlikte ciddigastrointestinal kanama sebebi olabilmektedir. Genellikle nonspesifik semptomlara yol açar.Dolayısıyla tanıda klinik şüphe en önemli husustur. Üst gastrointestinal endoskopi tanıda altınstandart özelliğini taşımaktadır. Tedavide genellikle medikal ajanlarla yüksek etkinlik elde etmekmümkündür. Çocuk doktorları bu nadir hastalık konusunda bilgi sahibi olmalı, klinik açıdangerekli görüldüğünde endoskopik incelme ihmal edilmemelidir

References

  • Warren J, Marshall B. Unidentified curved bacillus on gastric epithelium in chronic active gastritis. Lancet 1983; I: 1273- 1275.
  • Pacifico L, Anania C, Osborn JF, Ferraro F, Chiesa C. Consequences of Helicobacter pylori infection in children. World J Gastroenterol. 2010 Nov 7;16(41):5181-5194.
  • Calvet X, Ramírez Lázaro MJ, Lehours P, Mégraud F. Diagnosis and epidemiology of Helicobacter pylori infection. Helicobacter. 2013;18 Suppl 1:5-11.
  • Sherman PM. Appropriate strategies for testing and treating Helicobacter pylori in children: when and how? Am J Med 2004; 117 Suppl 5A: 30S-35S.
  • Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med 2002; 347: 1175-1186.
  • Kasırga E. Cocukluk Cağında Peptik Ulser Hastalığı. Turkiye Klinikleri J Pediatr Sci 2012; 8(1):11-16.
  • Macarthur C, Saunders N, Feldman W. Helicobacter pylori, gastroduodenal disease, and recurrent abdominal pain in children. JAMA 1995; 273: 729-734.
  • Roma E, Kafritsa Y, Panayiotou J, Liakou R, Constantopoulos A. Is peptic ulcer a common cause of upper gastrointestinal symptoms? Eur J Pediatr 2001; 160: 497-500.
  • Ecevıt ÇÖ, Özgenç F, Yüksekkaya HA, Ünal F, Arikan Ç, Yağci RV. Peptic ulcer disease in children: an uncommon disorder with subtle symptomatology. Turk J Gastroenterol. 2012;23(6):666-669.
  • Kato S, Nishino Y, Ozawa K, Konno M, Maisawa S, Toyoda S, Tajiri H, Ida S, Fujisawa T, Iinuma K. The prevalence of Helicobacter pylori in Japanese children with gastritis or peptic ulcer disease. J Gastroenterol 2004; 39: 734-738.
  • Kalach N, Bontems P, Koletzko S, Mourad-Baars P, Shcherbakov P, Celinska-Cedro D, Iwanczak B, Gottrand F, Martinez-Gomez MJ, Pehlivanoglu E, Oderda G, Urruzuno P, Casswall T, Lamireau T, Sykora J, Roma-Giannikou E, Veres G, Wewer V, Chong S, Charkaluk ML, Mégraud F, Cadranel S. Frequency and risk factors of gastric and duodenal ulcers or erosions in children: a prospective 1-month European multicenter study. Eur J Gastroenterol Hepatol. 2010 Oct;22(10):1174-1181.
  • Oderda G, Shcherbakov P, Bontems P, Urruzuno P, Romano C, Gottrand F, Gómez MJ, Ravelli A, Gandullia P, Roma E, Cadranel S, De Giacomo C, Canani RB, Rutigliano V, Pehlivanoglu E, Kalach N, Roggero P, Celinska-Cedro D, Drumm B, Casswall T, Ashorn M, Arvanitakis SN. Results from the pediatric European register for treatment of Helicobacter pylori (PERTH). Helicobacter 2007; 12: 150- 156
  • Tutar E, Ertem D, Kotiloglu Karaa E, Pehlivanoglu E. Endoscopic and histopathologic findings associated with H. pylori infection in very young children. Dig Dis Sci. 2009;54(1):111-117.
  • Yadav SK, Gupta V, El Kohly A, Al Fadhli W. Perforated duodenal ulcer: a rare complication of deferasirox in children. Indian J Pharmacol. 2013;45(3):293-294.
  • Cruze K, Snyder WH Jr. Acute perforation of the alimentary tract in infancy and childhood. Ann Surg. 1961;154:93-99.
  • Ford AC, Forman D, Hunt RH, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials. BMJ. 2014; 348:1-13.
There are 16 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Sebahat Çam This is me

Publication Date December 1, 2015
Published in Issue Year 2015 Volume: 17 Issue: 3

Cite

APA Çam, S. (2015). PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?. Duzce Medical Journal, 17(3), 133-135.
AMA Çam S. PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?. Duzce Med J. December 2015;17(3):133-135.
Chicago Çam, Sebahat. “PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?”. Duzce Medical Journal 17, no. 3 (December 2015): 133-35.
EndNote Çam S (December 1, 2015) PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?. Duzce Medical Journal 17 3 133–135.
IEEE S. Çam, “PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?”, Duzce Med J, vol. 17, no. 3, pp. 133–135, 2015.
ISNAD Çam, Sebahat. “PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?”. Duzce Medical Journal 17/3 (December 2015), 133-135.
JAMA Çam S. PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?. Duzce Med J. 2015;17:133–135.
MLA Çam, Sebahat. “PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?”. Duzce Medical Journal, vol. 17, no. 3, 2015, pp. 133-5.
Vancouver Çam S. PEDİATRİK PEPTİK ÜLSER HASTALIĞI ÖNEMLİ Mİ?. Duzce Med J. 2015;17(3):133-5.